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Unbound Medicine.
(Actinomadura)
611 results
  • Phytoremediation of PAH compounds by microbial communities in sodic soil. [Journal Article]
    Int J Phytoremediation. 2023 Jan 24 [Online ahead of print]Urana R, Yadav J, … Singh N
  • The PAH degrading microbial consortium was collected from sodic soil of the nursery of Guru Jambheshwar University of Science and Technology, Hisar, Haryana (India). And the soil was artificially amended with phenanthrene and naphthalene to isolate the PAHs degrading microbial consortium. The diversity of microbial consortium was analyzed using the NGS (Next Generation Sequencing) based metagenom…
  • Antibacterial Spirotetronate Polyketides from an Actinomadura sp. Strain A30804. [Journal Article]
    Molecules. 2022 Nov 24; 27(23)Ching KC, Chin EJ, … Kanagasundaram Y
  • Large scale cultivation and chemical investigation of an extract obtained from Actimonadura sp. resulted in the identification of six previously undescribed spirotetronates (pyrrolosporin B and decatromicins C-G; 7-12), along with six known congeners, namely decatromicins A-B (1-2), BE-45722B-D (3-5), and pyrrolosporin A (6). The chemical structures of compounds 1-12 were characterized via compar…
  • Structures, biosynthesis, and bioactivities of prodiginine natural products. [Review]
    Appl Microbiol Biotechnol. 2022 Dec; 106(23):7721-7735.Li P, He S, … Liu L
  • Prodiginines are a large family of microbial secondary metabolites with a core structure of tripyrrole rings. They exhibit not only diverse chemical structures but also rich biological activities, such as anti-cancer, anti-microbial, anti-algae, anti-parasitic, pesticides, and UV radiation resistance. The preferred cytotoxicity to cancer cells rather than normal cells indicates a good biological …
  • Actinomadura spongiicola sp. nov., isolated from the marine sponge Leucetta chagosensis. [Journal Article]
    Int J Syst Evol Microbiol. 2022 Aug; 72(8)Qin Q, Jiang L, … Lin HW
  • A novel actinomycete strain, named LHW52907T, was isolated from a marine sponge (Leucetta chagosensis) collected in the South China Sea. The strain developed branched mycelia without fragmentation and short spore chains in hook-and- spiral form with wrinkled surfaces, bearing no more 10 spores. The cell-wall hydrolysates contained meso-diaminopimelic acid as the diagnostic diamino acid. The sugar…
  • Actinomadura parmotrematis sp. nov., isolated from the foliose lichen, Parmotrema praesorediosum (Nyl.) Hale. [Journal Article]
    Int J Syst Evol Microbiol. 2022 Jul; 72(7)Somphong A, Poengsungnoen V, … Phongsopitanun W
  • A novel actinomycete strain PM05-2T was isolated from the lichen Parmotrema praesorediosum (Nyl.) Hale collected from Chaiyaphum Province, Thailand. The taxonomic position of the strain was studied using the polyphasic approach. Based on the morphology and chemotaxonomic properties, strain PM05-2T was identified as a member of the genus Actinomadura. The whole-cell hydrolysate contained meso-diam…
  • Characterizing the mucin-degrading capacity of the human gut microbiota. [Journal Article]
    Sci Rep. 2022 05 19; 12(1):8456.Glover JS, Ticer TD, Engevik MA
  • Mucin-degrading microbes are known to harbor glycosyl hydrolases (GHs) which cleave specific glycan linkages. Although several microbial species have been identified as mucin degraders, there are likely many other members of the healthy gut community with the capacity to degrade mucins. The aim of the present study was to systematically examine the CAZyme mucin-degrading profiles of the human gut…
  • Mycetoma in north-western Yemen: Clinico-epidemiological and histopathological study. [Journal Article]
    Indian J Dermatol Venereol Leprol. 2022 Sep-Oct; 88(5):615-622.Khatri ML, Al Kubati SAS, … Majeed SMA
  • Background Mycetoma is widespread in Yemen; however, there are only a few documented reports on the entity from this geographical area. Methods A prospective study of 184 cases of mycetoma (male 145 and female 39) from different regions of north-western Yemen was conducted between July 2000 and May 2014. Clinical profile was recorded in a standardized protocol. The diagnosis was based on clinical…
  • Kumemicinones A-G, Cytotoxic Angucyclinones from a Deep Sea-Derived Actinomycete of the Genus Actinomadura. [Review]
    J Nat Prod. 2022 04 22; 85(4):1098-1108.Zhang Z, In Y, … Igarashi Y
  • Chemical investigation of the fermentation products of a deep sea water-derived actinomycete, Actinomadura sp. KD439, identified seven new angucyclinones, designated as kumemicinones A-G (1-7), together with the known SF2315B and miaosporone E. NMR and MS spectroscopic analyses, combined with X-ray crystallography and quantum chemical calculations of NMR chemical shifts and electronic circular di…
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