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29 results
  • Local antibiotic therapy guided by microbiological diagnosis. [Journal Article]
  • JCJ Clin Periodontol 2002; 29(8):743-9
  • Mombelli A, Schmid B, … Lang NP
  • CONCLUSIONS: Therapy with tetracycline fibers guided by microbiological diagnosis effectively reduced P. gingivalis and A. actinomycetemcomitans locally, but was unable to completely eradicate the target organisms. Additional systemic antibiotic therapy further reduced P. gingivalis and A. actinomycetemcomitans. The observed persistence patterns suggest that reemergence of A. actinomycetemcomitans was due to recolonization, whereas the strikingly reproducible local reemergence of P. gingivalis in some sites indicated failed eradication.
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