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Unbound Medicine.
(Acute interstitial pneumonitis)
1,222 results
  • Hypersensitivity pneumonitis, allergic bronchopulmonary aspergillosis and other eosinophilic lung diseases. [Review]
    Curr Opin Immunol. 2020 Nov 06; 66:129-135.Barry J, Gadre A, Akuthota P
  • Hypersensitivity pneumonitis (HP) is traditionally classified into acute, subacute and chronic forms. A high index of suspicion and a detailed investigation into the patient's environment is the key to diagnosis and treatment of HP. Eosinophilic lung diseases can be broadly categorized as idiopathic (acute eosinophilic pneumonia, chronic eosinophilic pneumonia, eosinophilic granulomatosis with po…
  • Azacitidine-induced pneumonitis and literature review. [Journal Article]
    BMJ Case Rep. 2020 Oct 29; 13(10)Nguyen P, Safdar J, … Soubani A
  • We present a case of azacitidine-induced pneumonitis which is a rare adverse drug reaction and reported in less than 0.1% of cases. Common side effects of azacitidine are weakness, nausea, vomiting, constipation, injection site reactions, insomnia, among others. Our patient received azacitidine to treat her acute myeloid leukaemia and began to develop shortness of breath which progressed to dyspn…
  • Diagnosis of common pulmonary diseases in children by X-ray images and deep learning. [Journal Article]
    Sci Rep. 2020 10 15; 10(1):17374.Chen KC, Yu HR, … Lu HH
  • Acute lower respiratory infection is the leading cause of child death in developing countries. Current strategies to reduce this problem include early detection and appropriate treatment. Better diagnostic and therapeutic strategies are still needed in poor countries. Artificial-intelligence chest X-ray scheme has the potential to become a screening tool for lower respiratory infection in child. …
    Wiad Lek. 2020; 73(8):1593-1599.Fal AM
  • Allergic alveolitis (AA) is a group of diseases with an immunologic background evoked by chronic antigen inhalation. The diagnosis is difficult due to the diversity and non-specific character of symptoms and different clinical severity. AA is the third most often interstitial-lung-disease, comprising 4-15% of all interstitial diseases. It's often related to professional exposure. Farmer's lung, a…
  • Hamman-Rich Syndrome: A Diagnosis of Exclusion in the COVID-19 Pandemic. [Case Reports]
    Cureus. 2020 Aug 19; 12(8):e9866.Zhang Q, Raza A, … Madara J
  • Hamman-Rich syndrome is a rapidly progressive interstitial lung disease with acute respiratory distress syndrome physiology. It carries a grave prognosis and a high early mortality rate. It is often distinguished from other similar pulmonary pathologies based on the clinical course, laboratory findings, bronchoalveolar lavage testing, and pathology report. We detail a 77-year-old lady with no pri…
  • COVID-19 infection and its deadly cytokine storm in a young obese adult. [Case Reports]
    J Community Hosp Intern Med Perspect. 2020 Jul 03; 10(4):295-298.Abbas S, Ahmad A, Lacasse A
  • SARS-CoV-2 is a novel coronavirus that was initially described in Wuhan China in December 2019. In the USA (US), the person to be diagnosed with the novel Coronavirus infection (COVID) was on 19 January 2020. On 18 March 2020, a 31-year-old morbidly obese African American woman presented with severe dyspnea with associated hypoxemia, fever and bilateral interstitial pulmonary ground glass infiltr…
  • [Acute amiodarone pulmonary toxicity with low impregnation dose: case report]. [Journal Article]
    Medwave. 2020 Aug 14; 20(7):e7996.Cabrera-Rego JO, Luzurriaga Navas JD, Yanes Quintana AA
  • Amiodarone, considered a potent antiarrhythmic, is known to cause pulmonary toxicity. Chronic interstitial pneumonitis is the most common presentation. However, acute pulmonary toxicity is rare and has a higher case fatality rate. We present a 61-year-old patient with persistent atrial fibrillation who, after a one-month treatment with oral amiodarone at a low dose impregnation of 400 mg/day, dev…
  • Hypersensitivity pneumonitis. [Review]
    Nat Rev Dis Primers. 2020 08 06; 6(1):65.Costabel U, Miyazaki Y, … Selman M
  • Hypersensitivity pneumonitis (HP) is a complex syndrome caused by the inhalation of a variety of antigens in susceptible and sensitized individuals. These antigens are found in the environment, mostly derived from bird proteins and fungi. The prevalence and incidence of HP vary widely depending on the intensity of exposure, the geographical area and the local climate. Immunopathologically, HP is …
  • Olfactory Dysfunction in COVID-19 Patients: Prevalence and Prognosis for Recovering Sense of Smell. [Journal Article]
    Otolaryngol Head Neck Surg. 2020 Jul 14 [Online ahead of print]D'Ascanio L, Pandolfini M, … Di Stadio A
  • While olfactory dysfunction associated with coronavirus disease 2019 (COVID-19) has attracted considerable interest, few studies have tracked outcomes at serial time points or beyond 2 weeks. Furthermore, data are conflicting regarding whether COVID-19 severity correlates with degree of olfactory dysfunction. This prospective case-control study analyzed prevalence and severity of subjective loss …
  • Acute lupus pneumonitis as the initial presentation of systemic lupus erythematosus. [Journal Article]
    BMJ Case Rep. 2020 Jul 07; 13(7)Cantero C, Vongthilath R, Plojoux J
  • Systemic lupus erythematosus is a multisystem autoimmune disease with wide-ranging pleuropulmonary manifestations. Acute lupus pneumonitis is one of its uncommon complications. We report a 36-year-old woman with acute lupus pneumonitis as the initial presentation of systemic lupus erythematosus. Clinical, biological, radiological and functional improvements were noticed with the administration of…
  • Complications in Idiopathic Pulmonary Fibrosis: Focus on Their Clinical and Radiological Features. [Journal Article]
    Diagnostics (Basel). 2020 Jul 03; 10(7)Galioto F, Palmucci S, … Vancheri C
  • Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease with uncertain origins and pathogenesis; it represents the most common interstitial lung disease (ILD), associated with a pathological pattern of usual interstitial pneumonitis (UIP). This disease has a poor prognosis, having the most lethal prognosis among ILDs. In fact, the progressive fibrosis related to IPF could lead to the devel…
  • Rapidly fatal outcome of Covid-19 after successful emergency surgery during pandemic outbreak in Northern Italy. [Case Reports]
    Int J Surg Case Rep. 2020; 73:9-12.Montali F, Palmieri G, … Costi R
  • CONCLUSIONS: During a pandemic outbreak, the early identification of SARS-CoV-2 infection of an inside patient initially considered to be infection-free has a pivotal importance not only for the prompt patient's management, but also to avoid infection spreading to other patients and hospital personnel.In the reported case, a more precise information to the patient regarding the imperative necessity to inform the medical personnel of any person of his entourage presenting, at any time, any tell-tale sign, symptom or examination which may be attributed to COVID-19, may have had allowed to anticipate patient's isolation and examinations and procedures aimed at identifying such an infection.Persistent hyperleucocytosis and increased CRP serum level in spite of uneventful postoperative course were the only, aspecific markers of an ongoing SARS-CoV-2 infection before symptoms' onset, and should be considered in future clinical practice in order to adopt the prompt and appropriate patient management and limit COVID-19 contagion in surgical units.
  • COVID-19 and Acute Lupus Pneumonitis: Diagnostic and Treatment Dilemma. [Case Reports]
    J Investig Med High Impact Case Rep. 2020 Jan-Dec; 8:2324709620933438.Kichloo A, Aljadah M, … Solanki S
  • In this article, we present a case of a young female patient with previously diagnosed lupus pneumonitis, now with a flare and new superimposed COVID-19 infection that was treated with intravenous steroids. On computed tomography scans, she had extensive interstitial lung fibrosis in addition to a positive COVID-19 polymerase chain reaction test requiring 6 L of oxygen via nasal cannula on admiss…
  • Acute Hypersensitivity Pneumonitis Associated With a High Ki-67 Proliferative Index. [Case Reports]
    Cureus. 2020 Apr 30; 12(4):e7905.Nabrinsky E, Kamar A, … Stone A
  • Hypersensitivity pneumonitis (HSP) is an interstitial lung disease caused by exposure to a large range of environmental antigens. Inhaling aerosolized particles leads to a heightened immune response. HSP comes in acute, subacute, or chronic forms, all with their own potential clinical and radiographic findings. Mycobacterium avium complex (MAC) is the most common nontuberculous mycobacteria and i…
  • Clinical and radiological characteristics of e-cigarette or vaping product use associated lung injury. [Journal Article]
    Emerg Radiol. 2020 Oct; 27(5):495-501.Chidambaram AG, Dennis RA, … Rapp JB
  • CONCLUSIONS: Adolescents with suspected EVALI commonly present with subacute respiratory distress with abdominal pain. Imaging findings include ground-glass opacities, subpleural sparing, and basilar opacities, most consistent with organizing pneumonia or hypersensitivity pneumonitis. Recognition of the common imaging findings may have significant patient management implications, especially if the diagnosis is not suspected clinically. The lung function effects of vaping are consistent with mildly reduced airflow, which improves on follow-up testing, and reduced diffusion capacity, which, concerningly, does not improve.
  • Challenges and countermeasures of thoracic oncology in the epidemic of COVID-19. [Review]
    Transl Lung Cancer Res. 2020 Apr; 9(2):337-347.Guo H, Chen X, … Zhou C
  • Since December, 2019, a 2019 novel coronavirus disease (COVID-19) infected by the severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) emerged in Wuhan, Hubei province, and the epidemic situation has continued to spread globally. The epidemic spread of COVID-19 has brought great challenges to the clinical practice of thoracic oncology. Outpatient clinics need to strengthen the differenti…
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