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Unbound Medicine.
(Acute renal failure)
103,802 results
  • The kidney-brain pathogenic axis in severe falciparum malaria. [Review]
    Trends Parasitol. 2023 Feb 01 [Online ahead of print]Conroy AL, Datta D, … Wassmer SC
  • Severe falciparum malaria is a medical emergency and a leading cause of death and neurodisability in endemic areas. Common complications include acute kidney injury (AKI) and cerebral malaria, and recent studies have suggested links between kidney and brain dysfunction in Plasmodium falciparum infection. Here, we review these new findings and present the hypothesis of a pivotal pathogenic crossta…
  • Identification of AGXT2, SHMT1, and ACO2 as important biomarkers of acute kidney injury by WGCNA. [Journal Article]
    PLoS One. 2023; 18(2):e0281439.Wei J, Zhang J, … Qin Y
  • Acute kidney injury (AKI) is a serious and frequently observed disease associated with high morbidity and mortality. Weighted gene co-expression network analysis (WGCNA) is a research method that converts the relationship between tens of thousands of genes and phenotypes into the association between several gene sets and phenotypes. We screened potential target genes related to AKI through WGCNA …
  • Transplant Renal Vein Thrombosis Rescued in a Pediatric Patient Using Suction Thrombectomy. [Journal Article]
    Tex Heart Inst J. 2023 Jan 01; 50(1)Batra A, Pallister Z, … Galván NT
  • Renal vein thrombosis after kidney transplant is a rare but potentially graft-threatening event. As sequelae of this complication can range from brief acute kidney injury to total graft failure, it is necessary to maintain close clinical observation postoperatively. If posttransplant renal vein thrombosis does occur, recanalization may be attempted with mechanical thrombectomy, suction thrombecto…
  • Renal control of life-threatening malarial anemia. [Journal Article]
    Cell Rep. 2023 Feb 02; 42(2):112057.Wu Q, Sacomboio E, … Soares MP
  • Iron recycling prevents the development of anemia under homeostatic conditions. Whether iron recycling was co-opted as a defense strategy to prevent the development of anemia in response to infection is unclear. We find that in severe Plasmodium falciparum malaria, the onset of life-threatening anemia is associated with acute kidney injury (AKI), irrespective of parasite load. Using a well-establ…
  • Door-to-furosemide time and clinical outcomes in acute heart failure. [Journal Article]
    Eur J Emerg Med. 2023 Feb 01 [Online ahead of print]Marques P, Brito MT, … Friões F
  • Acute heart failure (AHF) is one of the main causes of unplanned hospitalization in patients >65 years of age and is associated with adverse outcomes in this population. Observational studies suggest that intravenous diuretic therapy given in the first hour of presentation for AHF was associated with favorable outcomes. To study the short-term prognostic associations of the timing of intravenous …
  • Nivolumab-induced autoimmune diabetes mellitus presenting as diabetic ketoacidosis in a patient with metastatic mucosal melanoma. [Journal Article]
    J Oncol Pharm Pract. 2023 Feb 03 [Online ahead of print]Goff CB, Plaxe SC, … Dasanu CA
  • CONCLUSIONS: Development of type 1 diabetes with the use of immune checkpoint inhibitors has been increasingly reported in the literature. The exact mechanism for autoimmune diabetes precipitated by nivolumab is yet to be elucidated. Patient education about the symptoms of diabetes and regular glucose monitoring cannot be overemphasized. Testing for antibodies against glutamic acid decarboxylase 65, insulin receptors, and islet cells may also prove useful. Human leukocyte antigen DQ and DR haplotyping prior to immune checkpoint inhibitor treatment might help determine susceptibility toward developing type 1 diabetes, and provide opportunities for earlier recognition, intervention, and possibly prevention.
  • Heat Stroke Leading to a Fatal Outcome. [Case Reports]
    Cureus. 2023 Jan; 15(1):e33226.Chalise SN, Mirza E, Malik R
  • Heat stroke (HS) can cause several physiological changes in the body. In its most severe form, it can cause multi-organ failure including encephalopathy, circulatory shock, liver failure, renal failure, disseminated intravascular coagulation, and rhabdomyolysis among others. HS is a preventable condition; however, it can be life-threatening in severe forms. We present a case of HS in a 54-year-ol…
  • [A Case Report of Subcutaneous Nodular Fat Necrosis Caused by Obstructive Pancreatitis Due to IPMN]. [Journal Article]
    Gan To Kagaku Ryoho. 2022 Dec; 49(13):1765-1767.Urabe S, Yamada D, … Eguchi H
  • A 72-year-old man underwent hemodialysis because of end-stage renal failure. The patient often suffered acute pancreatitis and was diagnosed with main duct type intraductal papillary mucinous neoplasm(IPMN). Moreover, skin erythema with pain occurred and was treated as cellulitis using antibiotics; however, the skin lesions did not improve. Skin pathological findings indicated subcutaneous nodula…
  • Cytoplasmic HMGB1 induces renal tubular ferroptosis after ischemia/reperfusion. [Journal Article]
    Int Immunopharmacol. 2023 Jan 31; 116:109757.Zhao Z, Li G, … Zeng R
  • As a damage-associated molecular pattern molecule, high-mobility group box 1 (HMGB1) is well-studied and is released from injured tubular epithelial cells to trigger cell death. However, the role of intracellular HMGB1 induced cell death during acute kidney injury (AKI) is poorly understood. We showed that cytosolic HMGB1 induced ferroptosis by binding to acyl-CoA synthetase long-chain family mem…
  • Is Low-Titer Group O Whole Blood Truly a Universal Blood Product? [Journal Article]
    J Am Coll Surg. 2022 Nov 28 [Online ahead of print]Brill JB, Mueck KM, … Cotton BA
  • CONCLUSIONS: LTOWB appears to be a safe product for universal use across all blood groups. Group B recipients arrive with worse physiologic values associated with hemorrhagic shock whether receiving LTOWB or standard component products.
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