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(Acute respiratory distress syndrome ARDS )
59,144 results
  • Possibility of averting cytokine storm in SARS-COV 2 patients using specialized pro-resolving lipid mediators. [Review]
    Biochem Pharmacol. 2023 Jan 30 [Online ahead of print]Yasmeen N, Harikrishnan S, … Kumar V
  • Fatal "cytokine storms (CS)" observed in critically ill COVID-19 patients are consequences of dysregulated host immune system and over-exuberant inflammatory response. Acute respiratory distress syndrome (ARDS), multi-system organ failure, and eventual death are distinctive symptoms, attributed to higher morbidity and mortality rates among these patients. Consequent efforts to save critical COVID…
  • Lightning Strike Presenting as Fatal Lung Contusion: A Case Report. [Case Reports]
    Cureus. 2022 Dec; 14(12):e33125.Patel S, Yelne P, … Kakde Y
  • Electrical injuries to humans from a lightning strike are associated with significant rates of morbidity and fatality. High-voltage injuries including those caused by lightning strikes are pulmonary edema, pulmonary contusion, acute respiratory distress syndrome, and pulmonary hemorrhages. Patients who get injured experience secondary trauma in addition to direct and indirect injury. In this repo…
  • Personalized medicine targeting different ARDS phenotypes: The future of pharmacotherapy for ARDS? [Journal Article]
    Expert Rev Respir Med. 2023 Feb 01 [Online ahead of print]Blanchard F, James A, … Constantin JM
  • Acute respiratory distress syndrome (ARDS) still represents a major challenge with high mortality rates and altered quality of life. Many well-designed studies have failed to improve ARDS outcomes. Heterogeneity of etiologies, mechanisms of lung damage, different lung mechanics, and different treatment approaches may explain these failures. At the era of personalized medicine, ARDS phenotyping is…
  • Natural Immunomodulators Treat the Cytokine Storm in SARS-CoV-2. [Review]
    Adv Pharm Bull. 2023 Jan; 13(1):79-87.Abbas HS, Abd-Elhakeem MM, … Nabil MA
  • Recently, the world has been dealing with a destructive global pandemic Coronavirus disease 2019 (COVID-19) infection, since 2020; there were millions of infections and hundreds of thousands of deaths worldwide. With sequencing generations of the virus, around 60% are expected to become infected during the pandemic. Unfortunately, no drug or vaccine has been approved because no real evidence from…
  • Reduced circulating BMP9 and pBMP10 in hospitalized COVID-19 patients. [Journal Article]
    Pulm Circ. 2023 Jan; 13(1):e12192.Dunmore BJ, Upton PD, … Morrell NW
  • Similar to other causes of acute respiratory distress syndrome, coronavirus disease 2019 (COVID-19) is characterized by the aberrant expression of vascular injury biomarkers. We present the first report that circulating plasma bone morphogenetic proteins (BMPs), BMP9 and pBMP10, involved in vascular protection, are reduced in hospitalized patients with COVID-19.
  • Construction of human three-dimensional lung model using layer-by-layer method. [Journal Article]
    Tissue Eng Part C Methods. 2023 Jan 31 [Online ahead of print]Akamatsu Y, Akagi T, … Akashi M
  • The respiratory tract is one of the frontline barriers for biological defense. Lung epithelial intercellular adhesions provide protection from bacterial and viral infections, and prevent invasion into deep tissues by pathogens. Dysfunction of lung epithelial intercellular adhesion caused by pathogens is associated with development of several diseases, such as acute respiratory distress syndrome (…
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