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(Adenocarcinoma of small intestine)
6,094 results
  • The Impact of Food Bioactives on Health: in vitro and ex vivo models [BOOK]
  • BOOKSpringer: Cham (CH)
  • Verhoeckx K, Cotter P, … Wichers HMartínez-Maqueda D, Miralles B, … Recio I
  • The human colon adenocarcinoma cell line HT29, is not only used to study the biology of human colon cancers, but it is receiving special interest in studies focused on food digestion and bioavailabil...
  • The elusive small bowel adenocarcinoma in the terminal ileum-A case report. [Journal Article]
  • IJInt J Surg Case Rep 2018 Apr 27; 47:97-99
  • Ma JLG, Strauss PN
  • CONCLUSIONS: Clinical presentation of small bowel adenocarcinoma is often non-specific, which leads to a delay in diagnosis. As a result, disease is often advanced by the time of diagnosis. Upper and lower endoscopy is useful in detecting tumours in the duodenum and terminal ileum. Video capsule endoscopy allows visualisation of the entire small bowel mucosa. Enteroscopy can also be used to obtain biopsies and perform therapeutic interventions. CT is able to detect abnormalities in 80% of patients, while CT and MR (magnetic resonance) enteroclysis give better visualisation of the mucosa and mural thickness. Surgical exploration may be indicated in patients with a strong clinical suspicion.In conclusion, small bowel malignancies are rare and clinicians are reminded to have a high index of suspicion for small bowel malignancies in patients who present with non-specific abdominal symptoms.
  • A rare Krukenberg tumor arising from a primary adenocarcinoma of the small intestine. [Journal Article]
  • TJTaiwan J Obstet Gynecol 2018; 57(2):319-322
  • An-Chieh Liu A, Chen CH, … Chang CW
  • CONCLUSIONS: The primary lesion of a Krukenberg tumor is generally too small to be detected. Thus, careful radiographic and endoscopic exploration of the digestive system is necessary to detect the primary tumor. Immunohistochemical evaluation is also useful for determining the primary site of the adenocarcinoma.
  • Gemcitabine-based chemotherapy for advanced biliary tract carcinomas. [Review]
  • CDCochrane Database Syst Rev 2018 Apr 06; 4:CD011746
  • Abdel-Rahman O, Elsayed Z, Elhalawani H
  • CONCLUSIONS: In adults with advanced biliary tract carcinomas, the effects of gemcitabine or gemcitabine-based chemotherapy are uncertain on mortality and overall response compared with a range of inactive or active controls. The very low certainty of evidence is due to risk of bias, lack of information in the analyses and hence large imprecision, and possible publication bias. The confidence intervals do not rule out meaningful benefits or lack of effect of gemcitabine in all comparisons but one on mortality where gemcitabine plus cisplatin is compared with S-1 plus cisplatin. Gemcitabine-based regimens showed an increase in non-serious adverse events (particularly haematological toxicities). Further randomised clinical trials are mandatory, to further explore the best therapeutic options for adults with advanced biliary tract carcinomas.
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