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Unbound Medicine.
(Adjustment disorder)
37,225 results
  • Pixel-Based Swallow Measurements: Correcting Nonsquare Pixels. [Journal Article]
    J Speech Lang Hear Res. 2023 Jan 30 [Online ahead of print]Larsen D, Ikuma T, … Kunduk M
  • CONCLUSIONS: This research note demonstrates the effect of disregarding PAR to distance and area pixel-based parameters. In addition, we present a multilevel roadmap to prevent possible measurement errors that could occur. At the planning stage, the PAR of video source should be identified, and, at the analyses stage, video data should be prescaled prior to analysis with PAR-unaware software. No methodology in prior absolute or relative pixel-based studies reports adjustment to the PAR prior to measurements nor identify the PAR as a possible source of variation within the literature. Addressing PAR will improve the precision and stability of pixel-based VFSS findings and improve comparability within and across clinical and research settings.
  • Narrative review of migraine management in patients with renal or hepatic disease. [Review]
    Headache. 2023 Jan; 63(1):9-24.Stern JI, Datta S, … Robertson CE
  • CONCLUSIONS: For acute therapy, the use of NSAIDS should be limited, as these carry risk for both severe hepatic and renal disease. Triptans can be selectively used, often with dose guideline adjustments. Ubrogepant may be used in severe hepatic disease with dose adjustment and lasmiditan can be used in end stage renal disease. Though non-medicine strategies may be the most reasonable initial approach, many preventative medications can be used in the setting of hepatic and renal disease, often with dose adjustment. This review provides tables of guidelines, including reduced dosing recommendations, for the use of abortive and preventative migraine medications in hepatic and renal failure.
  • Remdesivir for the treatment of COVID-19. [Review]
    Cochrane Database Syst Rev. 2023 01 25; 1:CD014962.Grundeis F, Ansems K, … Stegemann M
  • CONCLUSIONS: Based on the available evidence up to 31 May 2022, remdesivir probably has little or no effect on all-cause mortality or in-hospital mortality of individuals with moderate to severe COVID-19. The hospitalisation rate was reduced with remdesivir in one study including participants with mild to moderate COVID-19. It may be beneficial in the clinical course for both hospitalised and non-hospitalised patients, but certainty remains limited. The applicability of the evidence to current practice may be limited by the recruitment of participants from mostly unvaccinated populations exposed to early variants of the SARS-CoV-2 virus at the time the studies were undertaken. Future studies should provide additional data on the efficacy and safety of remdesivir for defined core outcomes in COVID-19 research, especially for different population subgroups.
  • Neural substrates of continuous and discrete inhibitory control. [Journal Article]
    Transl Psychiatry. 2023 Jan 24; 13(1):23.Howlett JR, Park H, Paulus MP
  • Inhibitory control dysfunctions play an important role in psychiatric disorders but the precise nature of these dysfunctions is still not well understood. Advances in computational modeling of real-time motor control using a proportion-integral-derivative (PID) control framework have parsed continuous motor inhibition into a preemptive drive component (signified by the Kp parameter) and a reactiv…
  • Mental health problems and admissions to hospital for accidents and injuries in the UK military: A data linkage study. [Journal Article]
    PLoS One. 2023; 18(1):e0280938.Chui Z, Leightley D, … Goodwin L
  • CONCLUSIONS: The findings suggest that accidents and injuries among military personnel are not always random events and that there are health and behavioural factors, including poor mental health and smoking, which are associated (with small effect sizes) with an increased risk of being involved in an accident. Clinicians treating individuals attending hospital after an accident should consider their healthcare needs holistically, including issues related to mental health and health damaging behaviours.
  • Initiation of Distress Screening in Oral Cancer Clinics in Sri Lanka. [Journal Article]
    Psychooncology. 2023 Jan 24 [Online ahead of print]Ratnasekera N, Perera I, … Jayasekara P
  • CONCLUSIONS: The Sinhala version of DT and PL were deemed a valid AD screening tool for patients with oral cancer in Sri Lanka to initiate distress screening in busy oral cancer clinics. However, further validation for the full spectrum of distress is needed, preferably with improvements to PL This article is protected by copyright. All rights reserved.
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