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Unbound Medicine.
(Adrenal crisis)
1,988 results
  • #corticophobia: a review on online misinformation related to topical steroids. [Review]
    Clin Exp Dermatol. 2023 Feb 02; 48(2):112-115.Finnegan P, Murphy M, O'Connor C
  • Misinformation in healthcare is at crisis level worldwide, with the internet as primary source of prevarication. Topical corticosteroids (TCS) are a safe and effective treatment used in multiple dermatological conditions. Nonadherence to prescribed TCS can be due to phobia secondary to misinformation. TCS phobia is a complex multifaceted phenomenon that exploits patients with skin disease, create…
  • Akutt binyrebarksvikt hos et barn. [Case Reports]
    Tidsskr Nor Laegeforen. 2023 Jan 31; 143(2)Holmberg NH, Haagensen AL
  • CONCLUSIONS: Acute adrenal crisis is a rare primary presentation of adrenal insufficiency, especially in the paediatric population. It is an important differential diagnosis of shock and has high morbidity and mortality.
  • Intracardiac paraganglioma with a cough as the first symptom. [Case Reports]
    J Cardiothorac Surg. 2023 Jan 17; 18(1):30.Jingyi C, Qing X, … Fanglin L
  • CONCLUSIONS: Pheochromocytomas and paragangliomas (PPGLs) are a kind of neuroendocrine tumors. PPGLs can cause secondary hypertension, and lead to a series of clinical syndromes, including myocardial injury, metabolic changes, and so on. The occurrence of PPGIs is related to gene mutation. Biochemical detection, imaging examination, and genetic testing can help diagnose. The tumor should be surgically removed as soon as possible after the diagnosis. As a functional tumor, PPGLs should be fully prepared before surgery to avoid anesthesia and huge fluctuations in blood pressure during and after surgery, or the occurrence of fatal hypertensive crisis and intractable hypotension after tumor resection. Adequate preoperative preparation directly affects the prognosis of patients after surgery. Therefore, multidisciplinary cooperation before, during, and after the operation is extremely important.
  • A case of shock after STEMI: Think beyond the cardiogenic one. [Case Reports]
    Clin Case Rep. 2023 Jan; 11(1):e6792.Falcetta A, Bonfanti E, … Lauria G
  • Acute ST-segment elevation myocardial infarction (STEMI) can typically complicate with the development of cardiogenic shock; nevertheless, other less frequent types of shock may occur, including adrenal crisis (AC). We describe a case of STEMI complicated by AC and, for the first time, AC-induced focal takotsubo syndrome.
  • Approach to the Patient: Preventing adrenal crisis through patient and clinician education. [Journal Article]
    J Clin Endocrinol Metab. 2023 Jan 11 [Online ahead of print]Ahmet A, Gupta A, … Constantacos C
  • Adrenal crisis continues to be an important cause of death despite being a preventable condition. Significant deficits in patient education in the prevention of adrenal crisis have been identified as a contributor to adrenal crisis risk despite the importance of patient education being highlighted in international guidelines. Deficits in clinician education have also been identified as risk facto…
  • Etiology, clinical characteristics and mortality among Indian patients with Addison's disease. [Journal Article]
    Endocr Connect. 2023 Jan 01 [Online ahead of print]Gunna S, Singh M, … Bhatia E
  • The etiology, presentation and mortality of patients with primary adrenal insufficiency (PAI) in developing countries may differ from economically developed nations. However, information in this regard is scanty. The aim of this study was to determine the etiology and compare the clinical characteristics and mortality in infectious and autoimmune causes of PAI in Indian patients. All eligible (n=…
  • Bladder paraganglioma treated with open partial cystectomy: a case report. [Case Reports]
    J Med Case Rep. 2022 Dec 25; 16(1):479.Aksakallı T, Kozubaev B, … Bulut N
  • CONCLUSIONS: The rarity of cases having been reported in the literature leads to uncertainties in the management of bladder paraganglioma. Adrenergic symptoms developing during transurethral resection should suggest paraganglioma in the differential diagnosis. A multidisciplinary approach and medical treatment are mandatory to prevent life-threatening complications such as hypertensive crisis, vascular collapse, and multiple-organ system failure. We aimed to report the clinical presentation that includes only macroscopic hematuria mimicking urothelial cancer and to emphasize the multidisciplinary approach in the treatment.
  • Perioperative Evaluation and Management of Patients on Glucocorticoids. [Review]
    J Endocr Soc. 2022 Dec 15; 7(2):bvac185.Chen Cardenas SM, Santhanam P, … Hamrahian AH
  • Myriad questions regarding perioperative management of patients on glucocorticoids (GCs) continue to be debated including which patients are at risk for adrenal insufficiency (AI), what is the correct dose and duration of supplemental GCs, or are they necessary for everyone? These questions remain partly unanswered due to the heterogeneity and low quality of data, studies with small sample sizes,…
  • A case of unilateral post-COVID-19 adrenal haemorrhage and follow-up during pregnancies. [Journal Article]
    Endocrinol Diabetes Metab Case Rep. 2022 Dec 01; 2022Mangone A, Yousuf Q, … Ronchi CL
  • The spectrum of endocrine-related complications of COVID-19 infection is expanding; one of the most concerning of which is adrenal haemorrhage due to the risk of catastrophic adrenal crisis. In this study, we present a case that highlights the challenging management of a large, indeterminate unilateral adrenal mass during pregnancy and draws attention to a rare yet probably underestimated complic…
  • Autoimmune Polyglandular Syndrome Type II: A Case Report. [Case Reports]
    Cureus. 2022 Nov; 14(11):e31641.Jamal H, LaLoggia M, Harjai N
  • Autoimmune polyglandular syndromes (APS) are polyendocrinopathies characterized by autoimmune dysfunction of multiple endocrine organs. We present the case of a 23-year-old male with a past medical history of autoimmune thyroiditis diagnosed seven months prior who presented with a chief complaint of six months of fatigue, shortness of breath, and weight loss. Physical exam was remarkable for glob…
  • Rare cause of a resistant hypertension in a middle-aged man: A case report. [Case Reports]
    Clin Case Rep. 2022 Dec; 10(12):e6606.Marecek R, De Keyzer E, … Laura I
  • Congenital adrenal hyperplasia associated to 11-beta-hydroxylase deficiency is a rare cause of secondary hypertension, usually discovered during childhood; however, a late diagnosis in adults has also been reported. Despite low cortisol levels, accumulated adrenal steroid precursors can activate the glucocorticoid receptor and thus protect the patient against adrenal crisis.
    J Clin Endocrinol Metab. 2022 Dec 09 [Online ahead of print]Wright JJ, Johnson DB
  • Immune checkpoint inhibitors (ICI) are cancer therapies that are approved in at least 19 different cancers. They function by stimulating immune cell responses against cancer, and their toxicities comprise a host of autoinflammatory syndromes that may impact any organ system. Endocrine toxicities occur in as high as 25-50% of ICI recipients, depending on the treatment regimen used. These toxicitie…
  • Pheochromocytoma-induced Subarachnoid and Intracerebral Hemorrhage. [Case Reports]
    J Endocr Soc. 2022 Nov 17; 7(1):bvac176.Agoubi LL, Khot SP, … Zern NK
  • Pheochromocytomas are rare adrenal tumors that are often diagnosed in workup for endocrine causes of refractory hypertension, as an incidental imaging finding, or in patients with classic symptoms of headache, palpitations, and/or diaphoresis. We describe a case of pheochromocytoma presenting in a 63-year-old woman with spontaneous and multifocal subarachnoid and intracerebral hemorrhage without …
  • Intracardiac thrombosis following intravenous zoledronate treatment in a child with steroid-induced osteoporosis. [Case Reports]
    J Pediatr Endocrinol Metab. 2022 Nov 28 [Online ahead of print]Case SJ, Moon RJ, … Davies JH
  • CONCLUSIONS: Potential causes for intracardiac thrombosis in this patient include ventricular dysfunction due to acute adrenal crisis or electrolyte disturbance, and hypercoagulability due to the APR. Echocardiography should be considered in children with acute cardiovascular compromise following zoledronate. Stress-dose steroids to cover the APR and a reduced starting dose of zoledronate might have reduced the risk of this complication.
  • Pheochromocytoma Multisystem Crisis Complicated by Severe Acute Pancreatitis. [Journal Article]
    Intern Med. 2022 Nov 23 [Online ahead of print]Inaba H, Kaido Y, … Inoue G
  • A 43-year-old man developed headache, dizziness, abdominal pain, and vomiting. His blood pressure was 203/121 mmHg, heart rate 122 beats/min, body temperature 39.1 °C, and respiratory rate 24/min. He had elevated levels of creatinine at 2.95 mg/dL and lipase at 1,364 U/L as well as an extremely low calcium level at 5.2 mg/dL. Hypertriglyceridemia and hyperglycemia were seen. Chest and abdominal c…
  • Approach to the Patient with Adrenal Hemorrhage. [Journal Article]
    J Clin Endocrinol Metab. 2022 Nov 21 [Online ahead of print]Elhassan YS, Ronchi CL, … Baldeweg SE
  • Adrenal hemorrhage is an uncommon underrecognized condition that can be encountered in several clinical contexts. Diagnosing adrenal hemorrhage is challenging due to the non-specific clinical features. Therefore, it remains a diagnosis that is made serendipitously on imaging of acutely unwell patients rather than with prospective clinical suspicion. Adrenal hemorrhage can follow abdominal trauma …
  • The management of congenital adrenal hyperplasia during preconception, pregnancy, and postpartum. [Review]
    Rev Endocr Metab Disord. 2023 Feb; 24(1):71-83.Maher JY, Gomez-Lobo V, Merke DP
  • Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders of steroidogenesis of the adrenal cortex, most commonly due to 21-hydroxylase deficiency caused by mutations in the CYP21A2 gene. Although women with CAH have decreased fecundity, they are able to conceive; thus, if pregnancy is not desired, contraception options should be offered. If fertility is desired, women with…
  • An Unexpected Death Due to a Subclinical Pheochromocytoma After an Induced Abortion. [Case Reports]
    Am J Forensic Med Pathol. 2022 Dec 01; 43(4):376-379.Lupariello F, Mirri F, … Di Vella G
  • Deaths due to hypertensive crisis can be unexplained because of the impossibility to identify-before the decease-the specific cause of the crisis. In these cases, autopsy and microscopic examinations are needed. It can happen that the request to conduct these examinations can be submitted to forensic pathologists by prosecutors to ascertain medical malpractice claims. Indeed, we report the case o…
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