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(Adrenal gland cancer treatment of)
16,270 results
  • Acute psychotic episode inaugurating a primary hyperaldosteronism: a case report. [Case Reports]
    Pan Afr Med J. 2022; 43:103.Bouchalli WE, Mir KE, … Berrimi M
  • Psychiatrist manifestations-especially acute psychotic episode-of primary hyperaldosteronism is not very common in the scientific literature. The main symptoms are high blood pressure and hypokalemia, the diagnosis seems to be based on the determination of aldosterone and plasma renin activity, also the treatment includes majorly adrenalectomy. The take-away lesson from this case is to think of o…
  • Hypoxia signaling pathway: A central mediator in endocrine tumors. [Review]
    Front Endocrinol (Lausanne). 2022; 13:1103075.Watts D, Jaykar MT, … Wielockx B
  • Adequate oxygen levels are essential for the functioning and maintenance of biological processes in virtually every cell, albeit based on specific need. Thus, any change in oxygen pressure leads to modulated activation of the hypoxia pathway, which affects numerous physiological and pathological processes, including hematopoiesis, inflammation, and tumor development. The Hypoxia Inducible Factors…
  • [Morphological predictors of the efficacy of mitotane therapy in adrenocortical cancer]. [Journal Article]
    Probl Endokrinol (Mosk). 2023 Jan 08; 68(6):76-88.Tkachuk AV, Beltsevich DG, … Urusova LS
  • CONCLUSIONS: Consistent with the findings in our study, low expression of RRM1, CYP2W1 and SOAT1 was associated with worse DFS with antitumor therapy. The results of the work indicate the need to assess the levels of immunoreactivity of these markers in patients with ACC before starting treatment with mitotane in order to predict the efficiency of therapy.
  • Adrenal Gland Primary Neuroblastoma in an Adult Patient: A Case Report and Literature Review. [Case Reports]
    Medicina (Kaunas). 2022 Dec 23; 59(1)Telecan T, Andras I, … Crisan N
  • Neuroblastoma (NB) is an undifferentiated malignant tumor of the sympathetic ganglia, occurring in children under 5 years of age. However, it is a rare histology in adult patients, occurring once per every 10 million patients per year. We present the case of a 68-year-old male patient presented to our department for right lumbar pain, asthenia, loss of weight and altered general status. The contr…
  • The Role of Glucocorticoids in Breast Cancer Therapy. [Review]
    Curr Oncol. 2022 Dec 25; 30(1):298-314.Mitre-Aguilar IB, Moreno-Mitre D, … Mendoza-Almanza G
  • Glucocorticoids (GCs) are anti-inflammatory and immunosuppressive steroid molecules secreted by the adrenal gland and regulated by the hypothalamic-pituitary-adrenal (HPA) axis. GCs present a circadian release pattern under normal conditions; they increase their release under stress conditions. Their mechanism of action can be via the receptor-independent or receptor-dependent pathway. The recept…
  • Favourable prognosis in metastatic adrenal carcinoma: An unexpected outcome. [Case Reports]
    J Pak Med Assoc. 2022 Oct; 72(10):2101-2104.Hassan I, Sheikh A
  • The case of a 45-year-old male patient diagnosed with European Network for the Study of Adrenal Tumours (ENSAT) criteria, stage IV adrenocortical carcinoma (ACC) with unexpectedly prolonged survival is being reported. The patient underwent resection of stage IV ACC and despite suboptimal adherence to postoperative mitotane and chemotherapy, had a prolonged survival spanning almost seven years. Th…
  • Intraluminal Small Bowel Metastasis From Primary Lung Cancer. [Case Reports]
    World J Oncol. 2022 Dec; 13(6):409-416.Kosciuszek ND, Noel P, … Takahashi H
  • Lung cancer is the leading cause of cancer-related death worldwide, with frequent metastases to the brain, liver, adrenal glands, and bone. The incidence of intraluminal small bowel metastases of the lung is extremely rare and poorly documented within the literature. Few case studies have been published since the late 1980s and early 1990s. However, little is known about this rare form of metasta…
  • Adrenocortical carcinoma metastasis. A long story. [Case Reports]
    Ann Ital Chir. 2022 Dec 27; 11Mascioli F, Ossola P, … De Gyurgyokai SZ
  • CONCLUSIONS: This is a very unusual case of double ACC metastases, discovered after the end of standard follow-up and locally treated. The patient is recurrence-free 12 months after these procedures. Minimally invasive approach to treat symptomatic cholecystectomy was used in order to avoid pancreato-biliary complications. This study emphasized the necessity to realize tailored protocols for the follow-up of rare neoplasia, as ACC.
  • [Adrenal tumors: diagnostics, perioperative management and surgical treatment]. [Journal Article]
    Urologie. 2023 Jan 18 [Online ahead of print]Engelmann S, Burger M, Mayr R
  • Space-occupying lesions of the adrenal glands are one of the most frequent tumors; however, only a fraction of approximately 20% need further diagnostics and treatment. The diagnostic standard is native computed tomography (CT). For larger tumors and those that cannot be clearly classified as benign, the supplementary radiological modalities magnetic resonance imaging (MRI), contrast CT and 18F-f…
  • Intracardiac paraganglioma with a cough as the first symptom. [Case Reports]
    J Cardiothorac Surg. 2023 Jan 17; 18(1):30.Jingyi C, Qing X, … Fanglin L
  • CONCLUSIONS: Pheochromocytomas and paragangliomas (PPGLs) are a kind of neuroendocrine tumors. PPGLs can cause secondary hypertension, and lead to a series of clinical syndromes, including myocardial injury, metabolic changes, and so on. The occurrence of PPGIs is related to gene mutation. Biochemical detection, imaging examination, and genetic testing can help diagnose. The tumor should be surgically removed as soon as possible after the diagnosis. As a functional tumor, PPGLs should be fully prepared before surgery to avoid anesthesia and huge fluctuations in blood pressure during and after surgery, or the occurrence of fatal hypertensive crisis and intractable hypotension after tumor resection. Adequate preoperative preparation directly affects the prognosis of patients after surgery. Therefore, multidisciplinary cooperation before, during, and after the operation is extremely important.
  • The diagnosis and management of pheochromocytoma and paraganglioma during pregnancy. [Review]
    Rev Endocr Metab Disord. 2023 Feb; 24(1):49-56.Clifton-Bligh RJ
  • Diagnosis of pheochromocytoma or paraganglioma (PPGL) in pregnancy has been associated historically with high rates of materno-fetal morbidity and mortality. Recent evidence suggests outcomes are improved by recognition of PPGL before or during pregnancy and appropriate medical management with alpha-blockade. Whether antepartum surgery (before the third trimester) is required remains controversia…
  • [A Long-Term Survival Case of Paraganglioma Treated with Repeated Surgical Resection]. [Case Reports]
    Hinyokika Kiyo. 2022 Dec; 68(12):385-390.Izumi H, Nonomura D, … Mori K
  • We report a case of long-term survival in paraganglioma treated with repetitive surgery. A 32-year-old man was seen at the hospital because of hypertension and headache. On biochemical tests, elevated serum and urinary levels of noradrenaline were noted. Abdominal computed tomographic (CT) scan revealed a tumor 50 mm in diameter on the dorsal region of the inferior vena cava, superior to the rena…
  • Adrenocortical carcinoma with venous tumor invasion: is there a role for mini-invasive surgery? [Journal Article]
    Langenbecks Arch Surg. 2023 Jan 10; 408(1):17.Olivero A, Liu K, … Zhang X
  • CONCLUSIONS: The DFS of patients with VI from ACC is influenced by the staging and the extension of the venous invasion; the staging influences the OS. The mini-invasive approach seems feasible in selected patients; however, further studies investigating the oncological outcomes are needed. A mini-invasive approach for adrenal tumors with venous invasion is an explorable option in very selected patients.
  • Huge Hematoma as First Manifestation of Adrenocortical Carcinoma: A Case Report. [Case Reports]
    Am J Case Rep. 2023 Jan 09; 24:e937569.Świeczkowski-Feiz S, Kaszczewski P, … Gałązka Z
  • BACKGROUND Adrenocortical carcinoma (ACC) is a rare malignancy associated with unfavorable prognosis. It is mainly diagnosed in the fifth or sixth decade of life. Symptoms of ACC are associated with hormonal activity, presence of metastases, and size of the tumor. The treatment and prognosis depend on the stage of the disease assessed with the ENSAT staging system. CASE REPORT A 38-year-old White…
  • Stereotactic MR-Guided Radiotherapy for Adrenal Gland Metastases: First Clinical Results. [Journal Article]
    J Clin Med. 2022 Dec 30; 12(1)Michalet M, Bettaïeb O, … Riou O
  • Stereotactic MR-guided Radiotherapy (MRgRT) is an interesting treatment option for adrenal gland metastases (AGM). We reviewed data from 12 consecutive patients treated with MRgRT for an AGM in our center between 14 November 2019 and 17 August 2021. Endpoints were tolerance assessment, the impact of adaptive treatment on target volume coverage and organs at risk (OAR) sparing, local control (LC),…
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