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Unbound Medicine.
(Adrenal insufficiency acute)
2,266 results
  • Acute Spontaneous Bilateral Adrenal Hemorrhage Presenting as Hyponatremia. [Case Reports]
    Cureus. 2022 Dec; 14(12):e33060.Chippa VM, Chenna S, … Candula N
  • Bilateral adrenal hemorrhage is a very unusual cause of severe adrenal insufficiency and hyponatremia. It can result from trauma, infections, or antiphospholipid antibody syndrome and can be fatal if not diagnosed and treated early. Here, we present a 58-year-old Caucasian man with fatigue, altered sensorium, bradycardia, and hypotension. He denied any abdominal pain, recent trauma, or anti-plate…
  • Akutt binyrebarksvikt hos et barn. [Case Reports]
    Tidsskr Nor Laegeforen. 2023 Jan 31; 143(2)Holmberg NH, Haagensen AL
  • CONCLUSIONS: Acute adrenal crisis is a rare primary presentation of adrenal insufficiency, especially in the paediatric population. It is an important differential diagnosis of shock and has high morbidity and mortality.
  • The essentials of acute oncology. [Journal Article]
    Clin Med (Lond). 2023 Jan; 23(1):45-51.Palmer K, Wang E, … Tipples K
  • The general medical physician will often encounter patients who develop acute complications of their cancer diagnosis or anti-cancer treatment. Here we provide an overview of emergency solid tumour oncology to guide the initial management of these patients.
  • Immune checkpoint inhibitor-mediated hypophysitis: no place like home. [Journal Article]
    Clin Med (Lond). 2023 Jan; 23(1):81-84.Cooksley T, Knight T, … Adam S
  • Ambulatory emergency care forms a fundamental part of the strategy of trying to ensure safe and sustainable acute care services. Immune checkpoint inhibitor(ICI)-mediated hypophysitis is an important life-threatening complication of therapy. Patients presenting with clinical features and findings consistent with ICI-mediated hypophysitis were considered in the current study. In the absence of sev…
  • A PROSPECTIVE ANALYSIS OF THE METYRAPONE SHORT TEST USING TARGETED AND UNTARGETED METABOLOMICS. [Journal Article]
    Neuroendocrinology. 2023 Jan 16 [Online ahead of print]Seoudy AK, Schlicht K, … Laudes M
  • Introduction The present study aimed to prove the metyrapone short test in a day clinic to be suitable for examining the integrity of the hypothalamic-pituitary-adrenal (HPA) axis in patients with suspected secondary and tertiary adrenal insufficiency and to identify novel effector molecules in acute stress response. Methods 44 patients were prospectively enrolled. Based on stimulated 11-deoxycor…
  • A case of shock after STEMI: Think beyond the cardiogenic one. [Case Reports]
    Clin Case Rep. 2023 Jan; 11(1):e6792.Falcetta A, Bonfanti E, … Lauria G
  • Acute ST-segment elevation myocardial infarction (STEMI) can typically complicate with the development of cardiogenic shock; nevertheless, other less frequent types of shock may occur, including adrenal crisis (AC). We describe a case of STEMI complicated by AC and, for the first time, AC-induced focal takotsubo syndrome.
  • Etiology, clinical characteristics and mortality among Indian patients with Addison's disease. [Journal Article]
    Endocr Connect. 2023 Jan 01 [Online ahead of print]Gunna S, Singh M, … Bhatia E
  • The etiology, presentation and mortality of patients with primary adrenal insufficiency (PAI) in developing countries may differ from economically developed nations. However, information in this regard is scanty. The aim of this study was to determine the etiology and compare the clinical characteristics and mortality in infectious and autoimmune causes of PAI in Indian patients. All eligible (n=…
  • Seizure from water intoxication following bowel preparation: a case report. [Case Reports]
    BMC Nephrol. 2022 12 15; 23(1):402.Chiang TH, Tan JH, … Fang KC
  • CONCLUSIONS: In addition to the use of certain well-documented medications and the presence of comorbidities that can lead to hyponatremia, clinicians should also be aware of the use of desmopressin as an important risk factor. Thorough history taking can guide individualized bowel preparation regimens to minimize the risk of undesired complications.
  • Autoimmune polyendocrine syndrome II presenting paradoxically as Takotsubo cardiomyopathy: a case report and reappraisal of pathophysiology. [Journal Article]
    Egypt Heart J. 2022 Dec 13; 74(1):82.Batta A, Gupta AK, … Wander GS
  • CONCLUSIONS: Intricate relationship and interplay exist between the steroid hormones and catecholamines in the pathogenesis of TCM. Steroid hormones not only potentiate the actions of catecholamines, but they also regulate and channelize catecholaminergic actions preventing their deleterious effects on the cardiac tissue. Hence, both steroid deficiency and exogenous steroid replacement may precipitate TCM. Evidence from more such cases and larger perspective studies in future will further improve our understanding of this complex disease process and its myriad associations.
  • Pituitary apoplexy and COVID-19 vaccination: a case report and literature review. [Case Reports]
    Front Endocrinol (Lausanne). 2022; 13:1035482.Aliberti L, Gagliardi I, … Ambrosio MR
  • A 50-year-old man was admitted to our hospital for vomit, nausea, diplopia, and headache resistant to analgesic drugs. Symptoms started the day after his third COVID-19 mRNA vaccine (Moderna) whereas SARS-CoV-2 nasal swab was negative. Pituitary MRI showed recent bleeding in macroadenoma, consistent with pituitary apoplexy. Adverse Drug Reaction was reported to AIFA (Italian Medicines Agency).A s…
  • Approach to the Patient with Adrenal Hemorrhage. [Journal Article]
    J Clin Endocrinol Metab. 2022 Nov 21 [Online ahead of print]Elhassan YS, Ronchi CL, … Baldeweg SE
  • Adrenal hemorrhage is an uncommon underrecognized condition that can be encountered in several clinical contexts. Diagnosing adrenal hemorrhage is challenging due to the non-specific clinical features. Therefore, it remains a diagnosis that is made serendipitously on imaging of acutely unwell patients rather than with prospective clinical suspicion. Adrenal hemorrhage can follow abdominal trauma …
  • StatPearls: Adrenal Hemorrhage [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)MehmoodKhawar T.KTHameed Latif HospitalSharmanTariqTSouthern Ohio Medical CenterBOOK
  • Adrenal hemorrhage is an uncommon disorder characterized by bleeding into the suprarenal glands. The hematoma may be unilateral or bilateral, and the clinical presentation can range from nonspecific abdominal pain to catastrophic cardiovascular collapse. The etiologies for this unusual disorder are diverse. Potential causes include blunt abdominal trauma, septicemia, coagulopathies, anti-coagulan…
  • Endotext: Adrenal Insufficiency [BOOK]
    Endotext. MDText.com, Inc.: South Dartmouth (MA)Feingold KR, Anawalt B, … Wilson DPNicolaides NC, Chrousos GP, … Charmandari EBOOK
  • Adrenal insufficiency is a serious pathologic condition characterized by decreased production or action of glucocorticoids and/or mineralocorticoids and adrenal androgens. This life-threatening disorder may be classified as primary, secondary or tertiary, resulting from diseases affecting the adrenal cortex, the anterior pituitary gland or the hypothalamus, respectively. The clinical manifestatio…
  • StatPearls: Adrenal Insufficiency (Nursing) [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)Huecker MR, Bhutta BS, … Bossuah KABOOK
  • Adrenal insufficiency ranges from mild nonspecific symptoms to life-threatening shock condition. Adrenal insufficiency is a diagnosis that will not be made unless the clinician maintains a level of suspicion. The decreasing or suppressed adrenal function may be masked until stress or illness triggers an adrenal crisis.[1][2][3] An important distinction in these patients is the presence of mineral…
  • StatPearls: Adrenal Insufficiency [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)HueckerMartin R.MRUniversity of LouisvilleBhuttaBeenish S.BSSheikh Zayed Hospital, LahoreDominiqueElvitaEWyckoff Heights Medical CenterBOOK
  • The adrenal gland is made up of two parts, the cortex and the medulla. The adrenal cortex produces hormones necessary for normal body functioning; deficiency of these hormones results in adrenal insufficiency. The cortex is responsible for producing glucocorticoids, mineralocorticoids, and androgens. Destruction or dysfunction of the adrenal cortex mainly causes glucocorticoid and mineralocortico…
  • Recurrence of Hypophysitis After Immune Checkpoint Inhibitor Rechallenge. [Case Reports]
    Oncologist. 2022 Dec 09; 27(12):e967-e969.Park BC, Jung S, … Johnson DB
  • Immune checkpoint inhibitor (ICI)-induced hypophysitis is an immune-mediated pituitary inflammation that tends to cause long-term pituitary deficiency. Management of ICI-induced hypophysitis includes corticosteroids for acute inflammation and long-term hormone replacement due to irreversible pituitary cell damage. We report a case of recurrent hypophysitis following ICI rechallenge for metastatic…
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