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1,113 results
  • Potential use of 13-mer peptides based on phospholipase and oligoarginine as leishmanicidal agents. [Journal Article]
    Comp Biochem Physiol C Toxicol Pharmacol 2019; 226:108612Mendes B, Almeida JR, … Miguel DC
  • Phospholipase A2 toxins present in snake venoms interact with biological membranes and serve as structural models for the design of small peptides with anticancer, antibacterial and antiparasitic properties. Oligoarginine peptides are capable of increasing cell membrane permeability (cell penetrating peptides), and for this reason are interesting delivery systems for compounds of pharmacological …
  • [Experience of Professor Fan Yongsheng in treating arthralgia with insect drugs]. [Journal Article]
    Zhongguo Zhong Yao Za Zhi 2019; 44(4):845-848Wu GL, Li TY, Fan YS
  • National-level famous traditional Chinese medicine(TCM) doctor Professor Fan Yong-sheng has high-level accomplishments in the treatment of arthralgia. According to clinical diagnosis and dialectic,TCM with appropriate medicinal properties were flexibly applied,with a remarkable efficacy. Especially in the application of insect drugs,he has accumulated abundant clinical experience.According to the…
  • Functional recombinant single-chain variable fragment antibody against Agkistrodon acutus venom. [Journal Article]
    Exp Ther Med 2019; 17(5):3768-3774Zhang L, Cao Y, … Tian J
  • Agkistrodon acutus bites are conventionally treated with animal-derived antivenom, the use of which is limited due to allergic reactions and serum sickness. Thus in the present study, the genes of humanized antibodies produced in response to A. acutus venom were extracted from lymphocytes from patients bitten by A. acutus. A single-chain variable fragment (scFv) library against venom was construc…
  • Water relations of an insular pit viper. [Journal Article]
    J Exp Biol 2019; 222(Pt 9)Sandfoss MR, Lillywhite HB
  • Colonization of novel habitats often requires plasticity or adaptation to local conditions. There is a critical need to maintain hydration in terrestrial environments having limited water. Atypical populations of Florida cottonmouth snakes, Agkistrodon conanti, inhabit continental islands with no permanent sources of fresh water. Here, we report investigations related to how these insular snakes …
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