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(Akineton)
661 results
  • Neuroleptic malignant syndrome in pregnancy: case report and literature review. [Journal Article]
  • JMJ Matern Fetal Neonatal Med 2018 Feb 05; :1-4
  • Escobar-Vidarte MF, Loaiza-Osorio S, … Macías GE
  • CONCLUSIONS: A search in PubMed, Embase and Ovid from 1988 to 2016 resulted in seven cases reported in either pregnant or puerperal women. In general, NMS resolves within 3-14 days; most NMS cases reported during pregnancy have involved the use of haloperidol (5 case reports) which is concordant with this report. The obstetric results were good in cases reported, only two women showed signs, among them: hyperemesis gravidarum and preterm delivery. Most of the pregnant women who had NMS presented other associated comorbidities, being mostly of infectious origin. In other investigations, it has been affirmed that NMS can become lethal in adults; however, in our search for pregnant women with this disease, no associated mortality was found.NMS is seen infrequently during pregnancy. The clinical diagnosis requires high suspicion by the examiner. It is important that obstetricians timely recognize the condition.
  • Acute intoxications among Turkish children. [Journal Article]
  • MPMinerva Pediatr 2018; 70(1):46-50
  • Kizilyildiz BS, Karaman K, … Üner A
  • CONCLUSIONS: Our study revealed that pharmaceuticals were the most common cause of acute intoxications. While, insecticides-pesticides and plants were the leading non-pharmaceutic agents. Our data is important because it is one of few original reports on children with intoxication in Eastern Turkey.
  • Anticholinergic medication for antipsychotic-induced tardive dyskinesia. [Review]
  • CDCochrane Database Syst Rev 2018 01 17; 1:CD000204
  • Bergman H, Soares-Weiser K
  • CONCLUSIONS: Based on currently available evidence, no confident statement can be made about the effectiveness of anticholinergics to treat people with antipsychotic-induced tardive dyskinesia. The same applies for the withdrawal of such medications. Whether the withdrawal of anticholinergics may benefit people with antipsychotic-induced TD should be evaluated in a parallel-group, placebo-controlled randomised trial, with adequate sample size and at least 6 weeks of follow-up.
  • [Drug-Induced Akathisia]. [Journal Article]
  • BNBrain Nerve 2017; 69(12):1417-1424
  • Inada T
  • Akathisia consists of subjective inner restlessness, such as awareness of the inability to remain seated, restless legs, fidgetiness, and the desire to move constantly, and of objective increased mot...
  • Antiepileptic drugs in clinical development: differentiate or die? [Journal Article]
  • CPCurr Pharm Des 2017 Aug 09
  • Zaccara G, Schmidt D
  • CONCLUSIONS: Substantial improvements in the efficacy, specifically as pharmacological treatment of drug-resistant epilepsy is regarded, are not expected. New drugs should be developed to specifically target the biochemical alteration which characterizes the underlying disease and also include targets that contribute to epileptogenesis in relevant epilepsy models.
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