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(Alcohol withdrawal)
14,084 results
  • StatPearls [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Ghiasi Noman N American Un of the Caribbean School Med Marwaha Raman R Case Western Reserve Un/MetroHealth MC
  • Lorazepam is a benzodiazepine medication developed by DJ Richards. It went on the market in the United States in 1977. Lorazepam is commonly used as the sedative and anxiolytic of choice in the inpat...
  • Perioperative alcohol cessation intervention for postoperative complications. [Review]
  • CDCochrane Database Syst Rev 2018 Nov 08; 11:CD008343
  • Egholm JW, Pedersen B, … Tønnesen H
  • CONCLUSIONS: This systematic review assessed the efficacy of perioperative alcohol cessation interventions for postoperative complications and alcohol consumption. All three studies showed a significant reduction in the number of participants who quit drinking alcohol during the intervention period. Intensive alcohol cessation interventions offered for four to eight weeks to participants undergoing all types of surgical procedures to achieve complete alcohol cessation before surgery probably reduced the number of postoperative complications. Data were insufficient for review authors to assess their effects on postoperative mortality. No studies reported an effect on length of stay, and no studies addressed the prevalence of risky drinking in the longer term.Included studies were few and reported small sample sizes; therefore one should be careful about drawing firm conclusions based on these study results. All three studies were conducted in Denmark, and most participants were men. The included participants may represent a selective group, as they could have been more motivated and/or more interested in participating in clinical research or otherwise different, and effects may have been overestimated for both intervention and control groups in these studies. Trial results indicate that these studies are difficult to perform, that strong research competencies are necessary for future studies, and that further evaluation of perioperative alcohol cessation interventions in high-quality randomized controlled trials is needed. Once published and assessed, the one 'ongoing' study identified may alter the conclusions of this review.
  • Protocol for a randomised controlled trial of cognitive bias modification training during inpatient withdrawal from alcohol use disorder. [Journal Article]
  • TTrials 2018 Nov 01; 19(1):598
  • Manning V, Garfield JBB, … Verdejo-Garcia A
  • CONCLUSIONS: This study is the first multisite randomised controlled trial of cognitive bias modification delivered during acute alcohol withdrawal treatment. Withdrawal is theoretically an ideal period to deliver neurocognitive interventions due to heightened neuroplasticity and cognitive recovery. If effective, the low cost and easy implementation of CBM training means it could be widely used as a standard part of alcohol withdrawal treatment to improve treatment outcomes. Moderation analyses may help better determine whether certain subgroups of patients are most likely to benefit from it and therefore should be prioritised for CBM during alcohol withdrawal treatment.
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