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(Alcoholic and Toxic Liver Disease)
718 results
  • Interleukin-1 Family Cytokines: Keystones in Liver Inflammatory Diseases. [Review]
    Front Immunol 2019; 10:2014Barbier L, Ferhat M, … Barbarin A
  • The pyrogenic property being the first activity described, members of the interleukin-1 superfamily (IL-1α, IL-1β, IL-18, and the newest members: IL-33, IL-36, IL-37, and IL-38) are now known to be involved in several inflammatory diseases such as obesity, atherosclerosis, cancer, viral and parasite infections, and auto-inflammatory syndromes as well as liver diseases. Inflammation processes are …
  • The unfolded protein response and hepatic lipid metabolism in non alcoholic fatty liver disease. [Review]
    Pharmacol Ther 2019; :107401Song MJ, Malhi H
  • Nonalcoholic fatty liver disease is a major public health burden. Although many features of nonalcoholic fatty liver disease pathogenesis are known, the specific mechanisms and susceptibilities that determine an individual's risk of developing nonalcoholic steatohepatitis versus isolated steatosis are not well delineated. The predominant and defining histologic and imaging characteristic of nonal…
  • Relevance between Helicobacter pylori Infection and Non-Alcoholic Fatty Liver Disease in Birjand, Iran. [Journal Article]
    J Med Life 2019 Apr-Jun; 12(2):168-172Mohammadifard M, Saremi Z, … Akbari E
  • There is evidence that infection by H. pylori can have a critical proportion in the development of hepatocyte injury and both noncancerous and malignant liver conditions including non-alcoholic fatty liver disease (NAFLD). This is attributed to several mechanisms, the most important one being the toxic products of the bacterium H. pylori and oxidative injury for hepatocytes which promotes hepatic…
  • [Study on liver protection and hepatotoxicity of saikosaponin a based on zebrafish model]. [Journal Article]
    Zhongguo Zhong Yao Za Zhi 2019; 44(13):2662-2666Xia Q, Han LW, … Tu PF
  • Bupleuri Radix has both liver protection and hepatotoxicity. Saponins are the main pharmacodynamic and toxic components of Bupleuri Radix. Based on zebrafish physical model and the model of alcoholic fatty liver(AFL) pathology,the liver toxic and protective effect of saikosaponin a(SSa) were assessed. The results indicated that 1. 77 μmol·L-1 SSa showed protective effect to AFL zebrafish. 5. 30 μ…
  • Evidence for Toxic Advanced Glycation End-Products Generated in the Normal Rat Liver. [Journal Article]
    Nutrients 2019; 11(7)Takata T, Sakasai-Sakai A, … Takeuchi M
  • Glucose/fructose in beverages/foods containing high-fructose corn syrup (HFCS) are metabolized to glyceraldehyde (GA) in the liver. We previously reported that GA-derived advanced glycation end-products (toxic AGEs, TAGE) are generated and may induce the onset/progression of non-alcoholic fatty liver disease (NAFLD). We revealed that the generation of TAGE in the liver and serum TAGE levels were …
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