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6,044 results
  • The feasibility of dexamethasone omission in weekly paclitaxel treatment for breast cancer patients. [Journal Article]
  • SCSupport Care Cancer 2018 Aug 01
  • de Castro Baccarin AL, Irene MN, … Del Giglio A
  • CONCLUSIONS: Dexamethasone withdrawal from W3 to W12 in early stage breast cancer patients treated with weekly paclitaxel is feasible. The incidence of all grades of HSRs was comparable to that reported in trials with dexamethasone for 12 consecutive weeks, and no serious events (G3/G4) occurred. Studies with larger sample sizes are needed to confirm our results which are important, especially for patients for whom corticosteroids are contraindicated.
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