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6,062 results
  • Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study. [Journal Article]
  • HHeadache 2018 Nov 07
  • Hamilton KT, Robbins MS
  • CONCLUSIONS: While the majority of pregnant women with acute migraine received medications considered relatively safe in pregnancy, there was variation in treatment choice and sequence. Some acute medications considered potentially hazardous for fetal health and less effective for migraine (opioids and butalbital) were used frequently, whereas other treatments that may have low teratogenic risk (nerve blocks, IV fluid boluses, and triptans) were used less or not at all. These results indicate a need for developing guidelines and protocols to standardize acute treatment of migraine in pregnancy.
  • Cardiac arrest caused by diphenhydramine overdose. [Journal Article]
  • AMAcute Med Surg 2018; 5(4):380-383
  • Nishino T, Wakai S, … Inokuchi S
  • CONCLUSIONS: Although diphenhydramine is regarded as a safe medication, it shows dose-dependent toxicity. High intake is associated with death; therefore, caution should be exercised in cases of drug overdose. Developing a procedure for rapid measurement in the emergency department should be a priority.
  • Intraoperative angioedema induced by angiotensin II receptor blocker: a case report. [Journal Article]
  • PSPatient Saf Surg 2018; 12:27
  • Alhowary AA, Odat H, … Al-Omari A
  • CONCLUSIONS: The precise mechanism of angiotensin II receptor blocker-induced angioedema is still unknown and should be thoroughly investigated. This report demonstrates a unique case of intraoperative angiotensin II receptor blocker-induced angioedema. Potential differential diagnoses of postoperative facial edema are discussed in detail, including the prolonged prone positioning for posterior spine surgery. Anesthesiologists should be aware of such rare, but potentially dangerous, perioperative adverse reaction that can occur with angiotensin II receptor blockers use.
  • StatPearls [BOOK]
  • BOOKStatPearls Publishing: Treasure Island (FL)
  • Sicari Vincent V Kent Hospital Zabbo Christopher P. CP Kent Hospital/ UNECOM
  • Diphenhydramine, which is available as an over-the-counter medication, is a first-generation antihistamine that is used in a variety of conditions to treat and prevent dystonias, insomnia, pruritis, ...
  • Rapid infusion rituximab is well tolerated in patients with primary CNS lymphoma. [Journal Article]
  • COCNS Oncol 2018 Jul 01; 7(3):CNS19
  • Modelevsky L, Tizon R, … Kaley T
  • CONCLUSIONS: 11 patients received a total of 44 RRIs. Rituximab was dosed at 500 or 750 mg/m2. Premedication included acetaminophen and diphenhydramine. No infusion reactions occurred during any RRI. Two infusions were administered with steroids for neurologic symptoms at baseline (4.5%). Rapid administration of rituximab was safe and feasible for patients with PCNSL and at the higher doses received.
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