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(Allergic Rhinitis and Rhinosinusitis)
1,304 results
  • Topical Ectoine: A Promising Molecule in the Upper Airways Inflammation-A Systematic Review. [Review]
    Biomed Res Int 2019; 2019:7150942Casale M, Moffa A, … Rinaldi V
  • To date, topical therapies guarantee a better delivery of high concentrations of pharmacologic agents to the mucosa of the upper airways (UA). Recently, topical administration of ectoine has just been recognized as adjuvant treatment in the Allergic Rhinitis (AR) and Rhinosinusitis (ARS). The aim of this work is to review the published literature regarding all the potential therapeutic effects of…
  • Janus looks both ways: How do the upper and lower airways interact? [Review]
    Paediatr Respir Rev 2019de Benedictis FM, Bush A
  • Our understanding of the relationship between the upper and lower airways has greatly increased as a consequence of epidemiologic and pharmacologic studies. A consistent body of scientific evidence supports the concept that rhinitis, rhinosinusitis and asthma may be the expression of a common inflammatory process, which manifests at different sites of the respiratory tract, at different times. Th…
  • Novel therapeutic targets for allergic airway disease in children. [Review]
    Drugs Context 2019; 8:212590Giallongo A, Parisi GF, … Leonardi S
  • The aim of precision medicine is setting up targeted therapies for selected patients that would ideally have high effectiveness and few side effects. This is made possible by targeted therapy drugs that selectively act on a specific pathway. Precision medicine is spreading to many medical specialties, and there is increasing interest in the context of allergic airway diseases, such as allergic rh…
  • Measurement of nitric oxide and assessment of airway diseases in children: an update. [Journal Article]
    Minerva Pediatr 2019Pappalardo MG, Parisi GF, … Leonardi S
  • Nitric oxide (NO) is a gas synthesized by the inducible NO synthase enzyme in airway cells and it is thought to make important functions in the airway inflammation of several respiratory diseases. NO is even an oxygen-free radical and a powerful vasodilator released by endothelial NO synthase, involved in platelet aggregation and the regulation of vascular tone. At the respiratory level there are…
  • [The role and research progress of exosomes in chronic inflammatory diseases of airway]. [Review]
    Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2019; 33(7):681-684Zhao JM, Luo Q
  • Exosomes are nanovesicles secreted by a variety of living cells, which are involved in biological processes such as inflammation,antigen presentation,tumor invasion, and cell differentiation.They are a new mechanism of intercellular communication in the body.Airway chronic inflammatory diseases such as chronic rhinosinusitis,allergic rhinitis, chronic obstructive pulmonary disease,bronchial asthm…
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