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Unbound Medicine.
(Allergic vasculitis)
3,620 results
  • JAK inhibitors and autoimmune rheumatic diseases. [Review]
    Autoimmun Rev. 2023 Jan 14; 22(4):103276.Benucci M, Bernardini P, … Perricone C
  • The four Janus kinase (JAK) proteins and the seven Signal Transducers of Activated Transcription (STAT) mediate intracellular signal transduction downstream of cytokine receptors, which are involved in the pathology of allergic, autoimmune, and inflammatory diseases. The development of targeted small-molecule treatments with diverse selective inhibitory profiles, such as JAK inhibitors (JAKi), ha…
  • Localised chronic fibrosing vasculitis versus erythema elevatum diutinum. [Case Reports]
    BMJ Case Rep. 2023 Jan 02; 16(1)Tabata MM, Lin WM, … Chen ST
  • A woman in her 70s was referred for a painless plaque on the shin, present for 2 years and progressing in thickness. Examination revealed a large erythematous to violaceous indurated plaque with cobblestone appearance. Biopsy revealed an inflammatory infiltrate of neutrophils with scattered histiocytes, lymphocytes, eosinophils and plasma cells interspersed with areas of lamellar fibrosis and foc…
  • Cutaneous vasculitis: Lessons from COVID-19 and COVID-19 vaccination. [Review]
    Front Med (Lausanne). 2022; 9:1013846.Corrà A, Verdelli A, … Caproni M
  • Cutaneous vasculitis (CV) is an inflammatory skin-limited vascular disease affecting the dermal and/or hypodermal vessel wall. From the pathogenetic point of view, idiopathic forms are described as well as the induction from various triggers, such as drugs, infections, and vaccines. Following SARS-CoV-2 pandemic outbreak, cases of CV induced by both COVID-19 and COVID-19 vaccinations have been re…
  • Churg-Strauss syndrome: A case report. [Case Reports]
    J Family Med Prim Care. 2022 Sep; 11(9):5656-5658.Mert A
  • Churg-Strauss syndrome is a rare disease with systemic vasculitis and hypereosinophilia. It is accompanied by allergic rhinitis and asthma. Herein, we present a case of Churg-Strauss syndrome in a family medicine outpatient clinic. This report aimed to emphasize that if patients diagnosed with asthma have cough and/or hemoptysis that cannot be controlled despite interventions such as inhalation, …
  • [Translated article] Cutaneous and Mucosal Conditions Associated With Cocaine Use. [Review]
    Actas Dermosifiliogr. 2022 Dec 05 [Online ahead of print]Sánchez-Puigdollers A, Just-Sarobé M, Pastor-Jané L
  • Cocaine and some of its main adulterants, such as levamisole, can cause multiple cutaneous and mucosal manifestations, including ischemic complications, neutrophilic dermatoses, midline destructive lesions, and vasculitis associated with antineutrophil cytoplasmic antibodies (ANCAs). Striking systemic symptoms are generally not seen. In all these conditions, positive test results may be observed …
  • IgA Vasculitis With Concurrent ANCA-Positivity in the Setting of Bacterial Endocarditis. [Case Reports]
    R I Med J (2013). 2022 Dec 01; 105(10):52-55.Xiong M, Singer H, … Massoud CM
  • Cutaneous small vessel vasculitis (CSVV) or leukocytoclastic vasculitis (LCV) is a group of immune complex mediated vasculitides that affect dermal capillaries or post-capillary venules and classically presents as lower extremity palpable purpura. CSVV can be subdivided by antibody type and clinical features. In patients presenting with signs of LCV and ANCA positivity, clinicopathologic correlat…
  • Cutaneous vasculitis associated with molecular tergeted therapies: systematic review of the literature. [Review]
    Clin Rheumatol. 2023 Feb; 42(2):339-357.Ak T, Durmus RB, Onel M
  • Cutaneo us vasculitis (CV) has a broad spectrum of etiologies, and drugs are one of the main culprits. With the increasing use of targeted therapies in medicine, especially in rheumatology and oncology, the number of CV cases reported due to these drugs has increased. Therefore, the recognition and treatment of CV associated with targeted agents have become more and more important. In the literat…
  • Cutaneous Small Vessel Vasculitis: A Practical Guide to Diagnosis and Management. [Journal Article]
    Am J Clin Dermatol. 2023 Jan; 24(1):89-95.Micheletti RG
  • Cutaneous vasculitis may be a cutaneous manifestation of systemic vasculitis, a skin-limited variant of systemic vasculitis, or a type of single-organ vasculitis limited to the skin. Careful evaluation is necessary to distinguish these possibilities, differentiate skin-limited from systemic disease, and identify important underlying conditions, if present. Appropriate management depends on diseas…
  • Eosinophilic granulomatosis with polyangiitis. [Review]
    Postgrad Med. 2022 Dec 05 [Online ahead of print]Villa-Forte A
  • This review aims to describe the epidemiology, pathogenesis, clinical manifestations, diagnosis, treatment, and prognosis of eosinophilic granulomatosis with polyangiitis (EGPA). Eosinophilic granulomatosis with polyangiitis is a small to medium vessel necrotizing vasculitis, typically classified with granulomatosis with polyangiitis (GPA) and microscopic polyangitis (MPA) as antineutrophil cytop…
  • Torasemide-induced Vascular Purpura in the Course of Eosinophilic Granulomatosis with Polyangiitis. [Case Reports]
    Acta Dermatovenerol Croat. 2022 Sep; 30(2):116-118.Frątczak A, Polak K, … Bergler-Czop B
  • Torasemide is a loop diuretic with a molecule that is chemically similar to the sulphonamides described as eosinophilic granulomatosis with polyangiitis (EGPA) triggering drugs. The presented case is probably the first description of torasemide-induced vascular purpura in the course of EGPA. Any diagnosis of vasculitis should be followed by an identification of drugs that may aggravate the diseas…
  • Cutaneous vasculitis; An algorithmic approach to diagnosis. [Review]
    Front Med (Lausanne). 2022; 9:1012554.Alpsoy E
  • Vasculitides, characterized by inflammation and damage of blood vessels, encompass a broad spectrum of diseases. They can occur with different pathophysiological mechanisms and have a rich clinical heterogeneity depending on the vessel diameters they affect. Vasculitides may also present with a broad spectrum of severity, ranging from a mild self-limiting to a potentially life-threatening disease…
  • Leukocytoclastic vasculitis in a patient with syphilis and HIV coinfection. [Case Reports]
    Rev Inst Med Trop Sao Paulo. 2022; 64:e65.Ariza Ordoñez N, Sepúlveda VG, … Prada HAM
  • Leukocytoclastic vasculitis (LCV) is a small vessel vasculitis characterized by an inflammatory infiltrate composed of neutrophils with fibrinoid necrosis and "leukocytoclasia", a term that refers to nuclei disintegration into fragments. LCV is related to multiple conditions including ANCA-associated vasculitis, cryoglobulinemia, IgA vasculitis, infectious and systemic diseases such as rheumatoid…
  • A case of crescentic glomerulonephritis induced by afatinib for lung adenocarcinoma. [Journal Article]
    CEN Case Rep. 2022 Sep 30 [Online ahead of print]Morita D, Ito K, … Masutani K
  • Afatinib is a second-generation, oral, epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI). One of the most common adverse effects of affatinib is diarrhea, which may lead to acute kidney injury (AKI) due to severe plasma volume loss; however, no case of glomerular injury directly induced by afatinib has been reported to date. Here, we describe the case of a 53-year-old Japanese…
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