- Changes in dietary habits and weight status during the COVID-19 pandemic and its association with socioeconomic status among Iranians adults. [Journal Article]Front Public Health. 2022; 10:1080589.FP
- CONCLUSIONS: Overall, this study indicates changes in body weight, dietary habits and supplement intake during the pandemic. Therefore, the findings of this study are valuable for, health professionals and politicians to better public health practice and policy making.
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- Identification and characterization of aldehyde dehydrogenase (ALDH) gene superfamily in garlic and expression profiling in response to drought, salinity, and ABA. [Journal Article]Gene. 2023 Jan 26 [Online ahead of print]GENE
- In response to biotic and abiotic stressors, aldehydes are detoxified and converted to carboxylic acids by aldehyde dehydrogenases (ALDHs), which are enzymes that use NAD+/NADP+ as cofactors. Garlic (Allium sativum L.) has not yet undergone a systematic examination of the ALDH superfamily, despite the genome sequence having been made public. In this investigation, we identified, characterized, an…
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- Anti-inflammatory effects and molecular mechanisms of bioactive small molecule garlic polysaccharide. [Journal Article]Front Nutr. 2022; 9:1092873.FN
- Although garlic polysaccharides have been found to possess anti-inflammatory activities, anti-inflammatory study on small molecule water-soluble garlic polysaccharide (WSGP) is few. In this study, a novel WSGP with a molecular weight of 1853 Da was isolated by DEAE-52 and Sephadex G-100 column and the chemical composition was identified by monosaccharide composition and methylation analysis. Furt…
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- In vitro rumen fermentation pattern: insights from concentrate level and plant oil supplement. [Journal Article]
- The addition of oil to ruminant diets and oil fatty acid profiles are major factors that negatively affect ruminal fermentation, while increased forage level attenuates the adverse effects. The aim of this study was to determine the effects of oil source supplementation and concentrate level in the diet on in vitro ruminal fermentation kinetics. Pomegranate, garlic or sunflower oils were added (2…
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- Carbon dots as fluorescent nanoprobes for assay of some non-fluorophoric nitrogenous compounds of high pharmaceutical interest. [Journal Article]
- CONCLUSIONS: In a new way, this work successfully indicates, spectrometric methods for rapid detection of two non-fluorophoric nitrogenous compounds using potent carbon nanodots. Consequently, these green developed methods offer several benefits as simplicity, ease of quantification, accuracy and precision that encourage the application of the developed methods in routine analysis of Azithromycin and Rasagiline mesilate in quality control laboratories as analytical tool.
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- Green synthesis and characterization of zirconium nanoparticlefor dental implant applications. [Journal Article]
- Green synthesis is a promising and cost-effective technique to synthesize nanoparticles from plant extract. The present study shows the green synthesis of zirconium nanoparticles using the extract of ginger, garlic, and zirconium nitride. The obtained nanoparticles were studied for potential dental implant applications. The synthesized nanoparticles were characterized by Fourier Transform Infrare…
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- Phenotypic diversity and distinctiveness of the Belltall garlic landrace. [Journal Article]
- Among the Mediterranean horticultural landraces, garlic is one of the crops most threatened by genetic erosion. Due to its sexual sterility and to the incidence of seed-borne diseases, historical varieties have been widely replaced by commercial cultivars. In Catalonia, despite the historical relevance of the crop, solely the Belltall garlic landrace is cultivated for commercial purposes. To asse…
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- Vaccine or Garlic-Is It a Choice? Awareness of Medical Personnel on Prevention of Influenza Infections. [Journal Article]
- CONCLUSIONS: The study pointed to significant educational gaps regarding the role and effectiveness of influenza vaccination in the process of influenza virus infection and indicated a firm belief in medical myths, especially in the nursing community, related to protection against influenza virus infection.
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- Roles of Human Liver Cytochrome P450 Enzymes in Tenatoprazole Metabolism. [Journal Article]
- Tenatoprazole, a newly developed proton pump inhibitor candidate, was developed as an acid inhibitor for gastric acid hypersecretion disorders such as gastric ulcer and reflux esophagitis. It is known that tenatoprazole is metabolized to three major metabolites of 5'-hydroxy tenatoprazole, tenatoprazole sulfide, and tenatoprazole sulfone in human liver, primarily catalyzed by CYPs 2C19 and 3A4. W…
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- Efficient Elimination of Viruses from Garlic Using a Combination of Shoot Meristem Culture, Thermotherapy, and Chemical Treatment. [Journal Article]
- Garlic (Allium sativum L.) is a clonally propagated bulbous crop and can be infected by several viruses under field conditions. A virus complex reduces garlic yield and deteriorates the quality of the produce. In the present study, we aimed to eliminate Onion yellow dwarf virus (OYDV), Garlic common latent virus (GCLV), Shallot latent virus (SLV), and Allexiviruses from the infected crop using co…
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- Plant Essential Oils as Healthy Functional Ingredients of Nutraceuticals and Diet Supplements: A Review. [Review]
- Essential oils (EOs) are mixtures of volatile molecules endowed with health-promoting biological activities that go beyond their role as aromas and natural preservatives and can be exploited to develop functional foods and diet supplements. Their composition is briefly addressed along with regulatory aspects. The potential health benefit of human diet supplementation with EOs is outlined through …
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- Biochemical Composition, Antioxidant Activity and Antiproliferative Effects of Different Processed Garlic Products. [Journal Article]
- Garlic (Allium sativum L.) is a type of agricultural product that is widely used as a food spice, herb and traditional medicine. White garlic (WG) can be processed into several kinds of products, such as green garlic (GG), Laba garlic (LAG) and black garlic (BG), which have multiple health effects. In this study, GC-MS (gas chromatography-mass spectrometry), DPPH (1,1'-diphenyl-2-propionyl hydraz…
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- How Does Allium Leafy Parts Metabolome Differ in Context to Edible or Inedible Taxa? Case Study in Seven Allium Species as Analyzed Using MS-Based Metabolomics. [Journal Article]
- Genus Allium (F. Amaryllidaceae) includes a wide variety of edible foods widely consumed for their nutritive as well as health benefits. Seven Allium species, viz., chives, Egyptian leek, French leek, red garlic, white garlic, red onion, and white onion aerial parts were assessed for metabolome heterogeneity targeting both aroma and nutrients phytochemicals. A headspace solid-phase microextractio…
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- Quality and Shelf-Life Evaluation of Fresh Beef Stored in Smart Packaging. [Journal Article]
- Beef is a perishable food product susceptible to deterioration due to microbial growth. Therefore, this study aimed to ascertain how active and intelligent packaging performs by tracking the change in the quality of fresh beef stored at low temperatures. The intelligent packaging method employed indicators with solutions of Bromo Phenol Blue (BPB) and Phenol Red (PR) to monitor the change in beef…
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- Seleno-Analogs of Scaffolds Resembling Natural Products a Novel Warhead toward Dual Compounds. [Journal Article]
- Nowadays, oxidative cell damage is one of the common features of cancer and Alzheimer's disease (AD), and Se-containing molecules, such as ebselen, which has demonstrated strong antioxidant activity, have demonstrated well-established preventive effects against both diseases. In this study, a total of 39 Se-derivatives were synthesized, purified, and spectroscopically characterized by NMR. Antiox…
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- Persistent olfactory dysfunction in mild COVID-19 patients: A descriptive study of the characteristics and association with other symptoms. [Journal Article]
- CONCLUSIONS: There is some pathological selectivity for certain test pens, a higher prevalence of cognitive symptoms and many patients with combined parosmia and brain fog.
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- Development of Composite Edible Coating from Gelatin-Pectin Incorporated Garlic Essential Oil on Physicochemical Characteristics of Red Chili (Capsicum annnum L.). [Journal Article]
- Red chili is a climacteric fruit that still undergoes respiration after harvest. During storage, it is susceptible to mechanical, physical, and physiological damage and decay incidence, therefore a method is needed to protect it so that the quality losses can be minimized. One way this can be achieved is by applying edible coatings that can be made from hydrocolloids, lipids, or composites of bot…
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- Garlic (Allium sativum L.) as an Ally in the Treatment of Inflammatory Bowel Diseases. [Review]
- For centuries, garlic (Allium sativum) has been used both as a traditional remedy for most health-related ailments and for culinary purposes. Current preclinical investigations have suggested that dietary garlic intake has beneficial health effects, such as antioxidant, anti-inflammatory, antitumor, antiobesity, antidiabetic, antiallergic, cardioprotective, and hepatoprotective effects. Its thera…
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- Ethiopian Medicinal Plants Used for Respiratory Tract Disorders: Ethnomedicinal Review. [Review]
- Respiratory tract infections (RTIs) refer to infections in any part of the respiratory tract, which are common, with most of the world's population contracting at least one infection annually. These infections are becoming important causes of death and morbidity due to the rapid development of antimicrobial resistance that has resulted in reduced efficacy of existing drugs. Different local societ…
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- Self-assembled emulsion gel based on modified chitosan and gelatin: Anti-inflammatory and improving cellular uptake of lipid-soluble actives. [Journal Article]Int J Biol Macromol. 2023 Jan 16; 231:123300.IJ
- To obtain a green carrier for intestinal targeted delivery, an emulsion gel was designed by the self-assembly between gelatin and Pickering emulsion based on gallic acid modified-chitosan nanoparticles (GCS NPs). The emulsion gels loaded with garlic essential oil (Geo) and curcumin (Cur) were abbreviated as GOEG and GCEG, respectively. Meanwhile, the sodium alginate bead loaded with Geo (GOEGS3) …
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- Determination of phenolic compounds and their antioxidant activity of Iranian Allium sativum controversum extracts and their antimicrobial properties in fresh sausages. [Journal Article]
- In this study, Iranian Allium sativum controversum extracts, as a valuable source of bioactive compounds such as antioxidants, extracted by solvents were analyzed. Based on the analysis of total phenolic content (TPC) and total flavonoid content (TFC) and radical scavenging activity (1,1-diphenyl-2-picrylhydrazyl (DPPH)) of each extract, ethanol extracts were finally added to the sausage formulat…
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- A Full Factorial Design to Optimize Aminexil Nano Lipid Formulation to Improve Skin Permeation and Efficacy Against Alopecia. [Journal Article]AAPS PharmSciTech. 2023 Jan 18; 24(1):40.AP
- Aminexil (AMX) is considered to be one of the most widely used hair growth promoters. Nanostructured lipid carriers (NLC) are employed to increase the permeation of both lipophilic and hydrophilic drugs. Aminexil nanostructured lipid carrier (NLC) designed by pre-emulsion/ultrasonication method was utilized for alopecia treatment. For selecting optimum excipients, a solubility study was executed …
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- Herb-Drug Interactions and Their Impact on Pharmacokinetics: an Update. [Journal Article]Curr Drug Metab. 2023 Jan 16 [Online ahead of print]CD
- Herb medicine has a long history of application and is still used worldwide. With the development of complementary and alternative medicine, the interaction between herb and drugs has attracted more and more attention. Herb-drug interactions (HDI) could cause decreased efficiency, increased toxicity, and affect the drug absorption and disposition processes due to the interference of their pharmac…
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- Knowledge, attitudes and practices with regard to prophetic medicine during the COVID-19 pandemic in Saudi Arabia. [Journal Article]Eur Rev Med Pharmacol Sci. 2023 Jan; 27(1):352-358.ER
- CONCLUSIONS: The current study was conducted to evaluate the knowledge, attitudes, and practices of Muslim residents of Saudi Arabia concerning prophetic medicine during the COVID-19 pandemic. The study revealed that participants had good knowledge of prophetic medicine, including the use of natural products such as honey, ginger, garlic, and olive oil, as well as herbal products such as black seeds, and practices such as cupping. The study also showed that participants strongly believed that COVID-19 preventative measures - including quarantine, travel bans, and handwashing - were introduced by prophetic medicine. Practices including self-isolation, hand washing, and travel bans help prevent, treat and control diseases. They assist in maintaining good health and developing resistance to diseases.
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- Evaluation of Expression of Cytochrome P450 Aromatase and Inflammatory, Oxidative, and Apoptotic Markers in Testicular Tissue of Obese Rats (Pre)Treated with Garlic Powder. [Journal Article]
- Today, adolescent obesity is recognized as an epidemic and a cause of reproductive disorders. Decreased testosterone levels occur due to functional defects in the hypothalamus-pituitary axis, excessive activity of cytochrome P450 aromatase enzyme, and testicular dysfunction in these people. Oxidative damage, inflammation, and apoptosis are also the main mechanisms of testicular damage during obes…
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- Co-encapsulation of fish oil with essential oils and lutein/curcumin to increase the oxidative stability of fish oil powder. [Journal Article]Food Chem. 2023 Jan 11; 410:135465.FC
- The oxidation-resistant and multi-functional fish oil powders were produced by co-encapsulating fish oil with essential oils, lutein, and curcumin. The ovalbumin/alginate complex was used as the wall, and the wall-to-oil ratio was fixed at 1:1 based on yield, oil recovery, and internalization efficiency (IE). Surface oil was removed to better understand the characteristics of the fish oil powders…
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- Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis. [Journal Article]Phytother Res. 2023 Jan 14 [Online ahead of print]PR
- Several preclinical studies have focused on the beneficial effects of garlic on cardiovascular diseases, but the results were inconsistent. We performed a systematic review and meta-analysis on the effect of garlic powder tablets and aged garlic extract (AGE) in CAD patients, mainly focusing on blood pressure, coronary artery calcification, lipid profile, and inflammatory markers. We searched Pub…
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- The use of the nutritional supplements during the covid-19 outbreak in Saudi Arabia: A cross-sectional study. [Journal Article]
- CONCLUSIONS: The respondents' risk of these supplements' use may partially reflect the public's behavioral response during a pandemic. Future studies can document the health beliefs and motivations of nutritional supplement users.
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- Modification of the existing maximum residue levels for prothioconazole in garlic, onions and shallots. [Journal Article]
- In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Bayer SAS - Crop Science Division submitted a request to the competent national authority in the Netherlands to modify the existing maximum residue levels (MRLs) for the active substance prothioconazole in garlic, onions and shallots. The data submitted in support of the request were found to be sufficient to derive MRL pr…
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- Household ovicidal alternative for complementary control of Aedes aegypti in the Gran San Miguel de Tucuman agglomerate, Tucumán, Argentina. [Journal Article]Acta Trop. 2023 Jan 07; 239:106813.AT
- Aedes aegypti is closely related to human behavior that allows its establishment through the accumulation of urban solid waste where it lays resistant eggs. Generally, adulticides and larvicides are applied in excess, without ovicidal alternatives, and some household products can help reduce the abundance of quiescent eggs in breeding sites by affecting the viability of eggs. A community involved…
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