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47 results
  • Addition of a mast cell stabilizing compound to organ preservation solutions decreases lung reperfusion injury. [Journal Article]
  • JTJ Thorac Cardiovasc Surg 1998; 115(3):631-6; discussion 636-7
  • Barr ML, Carey JN, … Starnes VA
  • CONCLUSIONS: Addition of lodoxamide tromethamine to Euro-Collins or University of Wisconsin solution results in a marked decrease in lung reperfusion injury as demonstrated by increased oxygenation, decreased microvascular permeability, and increased compliance. These results are relevant as Euro-Collins and University of Wisconsin solutions are the most common clinically used lung preservation solutions. This study also highlights the deleterious role of resident mast cells in preservation injury.
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