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135,494 results
  • Hormone-sleep interactions predict cerebellar connectivity and behavior in aging females. [Journal Article]
    Psychoneuroendocrinology. 2023 Jan 25; 150:106034.Ballard HK, Jackson TB, … Bernard JA
  • Sex hormones fluctuate over the course of the female lifespan and are associated with brain health and cognition. Thus, hormonal changes throughout female adulthood, and with menopause in particular, may contribute to sex differences in brain function and behavior. Further, sex hormones have been correlated with sleep patterns, which also exhibit sex-specific impacts on the brain and behavior. As…
  • Oxytocin enhances progesterone production with upregulation of BMP-15 activity by granulosa cells. [Journal Article]
    Biochem Biophys Res Commun. 2023 Jan 23; 646:103-109.Yamamoto K, Nakano Y, … Otsuka F
  • To elucidate the reproductive role of oxytocin (OXT) in ovarian steroidogenesis and its functional interaction with bone morphogenetic proteins (BMPs), the effects of OXT on ovarian steroidogenesis were investigated by utilizing primary culture of rat granulosa cells and human granulosa KGN cells. Here we revealed that the OXT receptor was expressed in both rat and human granulosa cells and that …
  • Obesity is associated with alterations in antral follicle dynamics in eumenorrheic women. [Journal Article]
    Hum Reprod. 2023 Jan 27 [Online ahead of print]Oldfield AL, Vanden Brink H, … Lujan ME
  • CONCLUSIONS: Eumenorrheic women with obesity display evidence of suppressed antral follicle dynamics as judged by fewer recruitment events, selectable follicles, and anovulatory dominant follicles, as well as lower anti-Müllerian hormone (AMH) concentrations and an increased prevalence of luteal phase defects.This study was limited to an assessment of antral follicle dynamics and cannot inform on earlier stages of folliculogenesis. This study was observational and cannot address causation between obesity and altered antral follicle dynamics. Lastly, the data cannot be extrapolated to account for reduced fecundity and fertility in obesity.The increasing global prevalence of obesity necessitates an understanding of the mechanisms that underlie obesity-related adverse reproductive health outcomes. Eumenorrheic women with obesity demonstrate altered ovarian antral follicle and endocrine dynamics compared to their counterparts without obesity. The degree to which abnormal granulosa cell assembly and/or activity underlie the suboptimal luteinization and subfertility requires further investigation.
  • [Estradiol regulates the expression of plasma membrane Ca2+-ATPase isoform 2 in inner ear of rats]. [Journal Article]
    Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Dec 07; 57(12):1484-1490.Tian Q, Feng MY, … Zhuang JH
  • Objective: To observe the effects of estradiol on expression of plasma membrane Ca2+-ATPase isoform 2 in inner ear of rats. Methods: Twenty-five Three-months-old female Sprague-Dawley rats were randomly and equally divided into five groups by random number table mathod,with five rats in each group. Animals in Sham group were sham-operated while others were bilateral ovariactmized. One month after…
  • [Susceptibility and mechanism of sodium salicylate-induced tinnitus model in low estrogen rats]. [Journal Article]
    Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2022 Dec 07; 57(12):1479-1483.Lu Q, Zhang JN, … Li M
  • Objective: The susceptibility of tinnitus rats with low estrogen level induced by sodium salicylate and the changes of tumor necrosis factor α (TNF-α) in serum were observed to investigate the relationship between tinnitus occurrence and estrogen level. Methods: Forty-two healthy female Wistar rats were randomly divided into control group(n=6), normal group(n=6), sham operation group(n=6) and ova…
  • Ethanol potentiates FSH action in ovarian granulosa cells. [Journal Article]
    J Endocrinol. 2023 Jan 01 [Online ahead of print]Kasahara Y, Kishi H, … Okamoto A
  • There are many previous reports on the effects of ethanol on physiological function, including reports of elevated blood estrogen levels in women who drank alcohol. However, the mechanism of ethanol's effects on ovarian functions, such as follicle development and hormone secretion, hasn't been fully clarified. Therefore, in this study, we investigated the impacts of ethanol on these phenomena and…
  • Gut Microbial Succession Patterns and Metabolic Profiling during Pregnancy and Lactation in a Goat Model. [Journal Article]
    Microbiol Spectr. 2023 Jan 26 [Online ahead of print]Zhang K, Liu G, … Chen Y
  • The maternal gut microbiome affects the duration of pregnancy, delivery, and lactation. It also coordinates the stability of maternal metabolism by regulating and modulating inflammatory cytokines and reproductive hormones. This has been shown in several species; however, the situation in ruminants remains a black box. Here, we aimed to elucidate the relationship between the hindgut microbiota, m…
  • Hormonal abnormalities in alexithymia. [Journal Article]
    Front Psychiatry. 2022; 13:1070066.Goerlich KS, Votinov M
  • Alexithymia is a personality trait characterized by difficulties in emotion recognition and regulation that is associated with deficits in social cognition. High alexithymia levels are considered a transdiagnostic risk factor for a range of psychiatric and medical conditions, including depression, anxiety, and autism. Hormones are known to affect social-emotional cognition and behavior in humans,…
    Acta Endocrinol (Buchar). 2022 Jul-Sep; 18(3):398-400.Chen Y, Zhao M, … Yao H
  • We reported that in a 29-year-old male patient with hyperthyroidism, bilateral breast swelling appeared in three days after starting methimazole and gradually aggravated. Several days later, a small amount of transparent liquid could be squeezed out from bilateral mammary glands. Breast ultrasound confirmed gynaecomastia. The level of testosterone, estradiol and luteinizing hormone increased. Aft…
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