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(Alpha adrenoceptor blocking agents)
1,076 results
  • Vasoactive androgens: Vasorelaxing effects and their potential regulation of blood pressure. [Journal Article]
  • EREndocr Res 2018; 43(3):166-175
  • Isidoro L, Ferrer M, Perusquía M
  • CONCLUSIONS: The vasorelaxation induced by androgens is mainly mediated by blocking L-VOCCs and in lesser extent by the blockade of multiple signaling pathways operative during α-adrenoceptor-induced vasoconstriction. 5β-DHT regulates vascular resistance and BP by mainly acting in the mesenteric arterial bed, which may explain its outstanding antihypertensive response previously reported.
  • Treatment of cocaine cardiovascular toxicity: a systematic review. [Review]
  • CTClin Toxicol (Phila) 2016; 54(5):345-64
  • Richards JR, Garber D, … Lange RA
  • CONCLUSIONS: High-quality evidence for pharmacological treatment of cocaine cardiovascular toxicity is limited but can guide acute management of associated tachycardia, dysrhythmia, hypertension, and coronary vasospasm. Future randomized prospective trials are needed to evaluate new agents and further define optimal treatment of cocaine-toxic patients.
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