Try the Free App:
Prime PubMed app for iOS iPhone iPad
Prime PubMed app for Android
Prime PubMed is provided
free to individuals by:
Unbound Medicine.
3,036 results
  • Testicular ACE regulates sperm metabolism and fertilization through the transcription factor PPARγ. [Journal Article]
    J Biol Chem. 2023 Nov 20 [Online ahead of print]Shibata T, Bhat SA, … Khan Z
  • Testis angiotensin-converting enzyme (tACE) plays a critical role in male fertility, but the mechanism is unknown. Sperm motility and fertilization depend on energy metabolism. By using ACE C-domain knockout (CKO) mice which lack tACE activity, we found that ATP in CKO sperm was 9.4-fold lower than WT sperm. Similarly, an ACE inhibitor (ACEi) reduced ATP production in mouse sperm by 72%. Metaboli…
  • StatPearls: Ramipril [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)ChauhanMunishMPatelJayeshJUniversity of Iowa Hospitals and ClinicsAhmadFaranFCreighton University Medical CenterBOOK
  • Ramipril is an ACE inhibitor that is used for several indications. These include hypertension, prevention of heart failure progression post-myocardial infarction (MI). It is also used to reduce the risk of MI, stroke, and death in patients more than 55 years old with a high risk of atherosclerotic disease and major adverse cardiac events. This activity outlines the indications, mechanism of actio…
  • Effect of pharmacological heart failure drugs and gene therapy on Danon's cardiomyopathy. [Journal Article]
    Biochem Pharmacol. 2023 09; 215:115735.Yadin D, Guetta T, … Arad M
  • Danon disease is a rare X-linked genetic disease resulting from LAMP2 mutations leading to defective lysosomal function. Heart failure is the main causes of morbidity and mortality. Mice with an LAMP2-exon-6-deletion (L2[Δ6]), develop cardiac hypertrophy followed by dilated cardiomyopathy, in association with accumulation of autophagosomes, fibrosis and oxidative stress. We investigated the effec…
  • Can the current monkeypox affect the heart? A systematic review of case series and case report. [Systematic Review]
    BMC Cardiovasc Disord. 2023 06 28; 23(1):328.Sayad R, Siddiq A, … Elsaeidy AS
  • CONCLUSIONS: This study clarifies the potential for cardiac complications in monkeypox cases and provides avenues for future research to determine the underlying mechanism. Also, we found that the cases with pericarditis were treated with colchicine, and those with myocarditis were treated with supportive care or cardioprotective treatment (Bisoprolol and Ramipril). Furthermore, Tecovirimat is used as an antiviral drug for 14 days.
New Search Next