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3,366 results
  • MicroRNA-150 Modulates Ischemia-Induced Neovascularization in Atherosclerotic Conditions. [Journal Article]
  • ATArterioscler Thromb Vasc Biol 2017; 37(5):900-908
  • Desjarlais M, Dussault S, … Rivard A
  • CONCLUSIONS: Hypercholesterolemia is associated with reduced expression of miR-150, impaired Src signaling, and inefficient neovascularization in response to ischemia. Forced expression of miR-150 using a miR mimic could constitute a novel therapeutic strategy to improve ischemia-induced neovascularization in atherosclerotic conditions.
  • Effects of fenoterol on the skeletal system depend on the androgen level. [Journal Article]
  • PRPharmacol Rep 2017; 69(2):260-267
  • Śliwiński L, Cegieła U, … Zbrojkiewicz M
  • CONCLUSIONS: The results indicate the favorable action of fenoterol in conditions of testosterone deficiency, and its destructive influence upon the skeleton in the presence of androgens. The results confirm the key role of sympathetic nervous system in the regulation of bone remodeling.
  • Combined inhaled beta-agonist and anticholinergic agents for emergency management in adults with asthma. [Review]
  • CDCochrane Database Syst Rev 2017 01 11; 1:CD001284
  • Kirkland SW, Vandenberghe C, … Rowe BH
  • CONCLUSIONS: Overall, combination inhaled therapy with SAAC and SABA reduced hospitalisation and improved pulmonary function in adults presenting to the ED with acute asthma. In particular, combination inhaled therapy was more effective in preventing hospitalisation in adults with severe asthma exacerbations who are at increased risk of hospitalisation, compared to those with mild-moderate exacerbations, who were at a lower risk to be hospitalised. A single dose of combination therapy and multiple doses both showed reductions in the risk of hospitalisation among adults with acute asthma. However, adults receiving combination therapy were more likely to experience adverse events, such as tremor, agitation, and palpitations, compared to patients receiving SABA alone.
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