- [Retinal arterial occlusions (RAV) : S2e guidelines of the German Society of Ophthalmology (DOG), the German Retina Society (RG) and the German Professional Association of Ophthalmologists (BVA). Version: 7 October 2022]. [Review]Ophthalmologie. 2023 Jan; 120(Suppl 1):15-29.O
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- Ocular involvement in primary antiphospholipid syndrome: results of an extensive ophthalmological evaluation performed in the APS-Rio cohort. [Journal Article]Lupus. 2022 Nov 29 [Online ahead of print]L
- CONCLUSIONS: Vasomotor phenomena are importantly related to ocular symptoms in PAPS. Vascular tortuosity was a frequent finding in PAPS patients. Peripheral vascular tortuosity was associated with triple positivity and might be a biomarker of ischemic microvascular retinopathy due to PAPS.
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- Risk factors for ischemic cerebral stroke in patients with acute amaurosis fugax. [Journal Article]Can J Ophthalmol. 2022 Nov 08 [Online ahead of print]CJ
- CONCLUSIONS: Ischemic stroke and myocardial infarction were diagnosed in 0.3%-0.9% of hospitalized acute AF cases. Presence of hypercoagulable state, systemic vasculitis, CAD, and atherosclerosis each individually increased the risk of ischemic stroke by more than 3-fold; patients with these risk factors and acute AF should be closely monitored for developing acute systemic thrombotic events.
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- Ocular findings in asymptomatic patients with primary antiphospholipid syndrome. [Journal Article]Lupus. 2022 Dec; 31(14):1800-1807.L
- CONCLUSIONS: We provide novel evidence that approximately 20% of our asymptomatic PAPS patients without ocular symptoms have ophthalmologic findings that require early identification and careful surveillance focusing on minimizing systemic and vascular risk factors.
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- Ocular Migraine With Amaurosis Fugax of the Left Eye: A Case Report. [Case Reports]
- In amaurosis fugax, there is a sudden loss of vision in one eye. Patients gain their vision after a few minutes. The most common underlying cause is atherosclerosis of the internal carotid artery. Other underlying causes include vasospasm of the internal carotid artery, which leads to hypoperfusion and is seen in vasculitis, ocular migraines, and systemic lupus erythematosus. In this case study, …
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- Associations among Stroke, Myocardial Infarction, and Amaurosis Fugax in a Tertiary Referral Hospital in Taiwan. [Journal Article]
- CONCLUSIONS: A high incidence of internal carotid artery stenosis was observed after AF attack and was significantly associated with stroke. The incidence of MI and CRAO after AF was low. Among them, only CRAO was associated with carotid artery stenosis.
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- Amaurosis fugax and crescendo transient ischaemic attacks. [Journal Article]
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- [Unique visual symptom of amaurosis fugax: a case report]. [Case Reports]Rinsho Shinkeigaku. 2022 Sep 28; 62(9):722-725.RS
- We describe an unusual case of a 73-year-old man with amaurosis fugax. He had repeated transient monocular symptoms, one of which features lighting bolt-shaped glittering in the full visual field of the right eye since medical treatment for hypertension and diabetes mellitus started. A few days later, he felt difficulty in speech as well as sensory and motor disturbance in the left upper extremit…
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- Carotid dissection and central serous chorioretinopathy related to sarcoidosis-antiphospholipid syndrome: a case report. [Case Reports]
- Sarcoidosis is a chronic multisystemic disease, which can be rarely associated with autoimmune disorders, such as antiphospholipid syndrome (APS). Although amaurosis fugax is an uncommon complication, its presentation can unmask a carotid artery dissection (CAD) in these diseases. In addition, central serous chorioretinopathy (CSC) has been related to vascular disorders too. We presented a case o…
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- StatPearls: Anatomy, Head and Neck, Ophthalmic Arteries [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL)BOOK
- The ophthalmic artery is the first branch of the internal carotid artery. It comes off just distal to the cavernous sinus. The ophthalmic artery gives off many branches, which supply the orbit, meninges, face, and upper nose. When the ophthalmic artery is occluded, it can compromise vision. The ophthalmic artery comes off the internal carotid artery on the medial side of the anterior clinoid proc…
- StatPearls: Amaurosis Fugax [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL)BOOK
- The term amaurosis fugax is often used interchangeably to describe transient visual loss (TVL). However, it is employed widely in medicine to refer to any cause of transient monocular visual loss. Here, we will refer to amaurosis fugax only in the context of transient monocular visual loss associated with vascular thromboembolic events arising from the internal carotid arterial system. [1],[2],[3…
- StatPearls: Carotid Artery Stenosis [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL)BOOK
- Determining the difference between hemodynamic and embolic stroke in the presence of chronic internal carotid artery occlusion is important. Embolic symptoms may be from classic stroke or transient ischemic attack (TIA). Symptoms may include a contralateral motor or sensory deficits as well as amaurosis fugax. Hemodynamic symptoms may be similar to a classic stroke or TIA, but may also be less pr…
- A nationwide study of ocular manifestations leading to hospital contacts among patients with giant cell arteritis. [Journal Article]Semin Arthritis Rheum. 2022 10; 56:152071.SA
- CONCLUSIONS: In GCA, most cases of ocular manifestations leading to hospital contacts occur close to the time of diagnosis, with over one-third of cases occurring before the diagnosis, emphasizing the need for early recognition and treatment.
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- StatPearls: Carotid Artery Surgery [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL)BOOK
- Symptoms of extracranial carotid disease are most often caused by embolization. Arterial emboli account for approximately one-quarter of strokes in Europe and North America, and 80% of these originate from atherosclerotic lesions in a surgically accessible artery in the neck. The most common lesion is at the bifurcation of the carotid artery. Transcranial Doppler studies have shown that emboli ar…
- EnSite NavX mapping system guided implantation of a dual-chamber permanent pacemaker in a 41-year-old pregnant woman with a 4-year follow-up. [Case Reports]
- CONCLUSIONS: For PPI, ENMS is a feasible and reliable alternative to traditional X-ray fluoroscopy, especially when performing operations on pregnant patients. By bending the top of the active-fixation atrial lead into a U-shape during operation, the displacement of atrial lead may be avoided.
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- Thirty-Day Stroke and Mortality After Carotid Revascularization Among Octogenarians with Symptomatic Carotid Stenosis: Real-World Evidence from a National Surgical Quality Registry. [Journal Article]World Neurosurg. 2022 Jul 18 [Online ahead of print]WN
- CONCLUSIONS: Real-world analyses from a surgical quality registry show that CEA may be associated with lower odds of mortality compared with CAS among octogenarians.
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- Lights Off, Lights On: Amaurosis Fugax in Polycythemia. [Case Reports]
- There are many causes of amaurosis fugax, including polycythemia. Polycythemia is associated with elevated hematocrit levels and hyperviscosity, which can lead to ocular manifestations. We report a polycythemia patient with amaurosis fugax, who had resolution of ocular symptoms following venesection. A 29-year-old gentleman presented with a six-month history of episodic bilateral transient loss o…
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- Outcomes and role of shunting during carotid endarterectomy for symptomatic patients. [Journal Article]J Vasc Surg. 2022 11; 76(5):1289-1297.JV
- CONCLUSIONS: For symptomatic patients undergoing CEA with patch angioplasty, shunt placement was associated with an increased risk of cranial nerve injury without a reduction in postoperative stroke risk.
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- A point-of-care evaluation after visual loss following paraclinoid aneurysm repair: the role of sonographic and pupillometer assessment. [Case Reports]Acute Crit Care. 2022 Jul 05 [Online ahead of print]AC
- Visual complications represent common deficits following surgical or endovascular repair of paraclinoid aneurysms. Different etiologies should be investigated to prevent devastating consequences. Herein we present a point-of-care evaluation to investigate sudden visual loss after coiling of paraclinoid aneurysms. A 20-year-old male was admitted for a sudden headache. Head computed tomography show…
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- Teaching Video NeuroImage: Amaurosis Fugax Due to Recurrent Central Retinal Artery Occlusion by Microemboli. [Journal Article]Neurology. 2022 08 16; 99(7):313-314.Neur
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- Multiple attacks of transient monocular visual loss in a previously healthy man: a possible complication after COVID-19 vaccination? [Journal Article]
- CONCLUSIONS: To date, and the best of our knowledge, this is the first case report of multiple transient monocular visual loss attacks due to retinal vasospasm in a previously healthy middle-aged man documented by fundus retinography and OCTA. We discuss in this article the possible association of retinal vasospasm and Pfizer-BioNTech COVID-19 vaccination, probably related to vaccine-induced inflammation.
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- Patients with laboratory criteria of anti-phospholipid syndrome and 'non-criteria' manifestations: a multicenter cohort. [Journal Article]Scand J Rheumatol. 2022 Jun 20 [Online ahead of print]SJ
- CONCLUSIONS: 'Clinical non-criteria' patients displayed significant treatment use, predominantly haematological involvement, and less severe manifestations than definite APS controls. Some patients may additionally progress to future SLE. The impact of certain manifestations flags them as potential future contributors to classifying individuals as definite APS.
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- 18F-NaF PET/MRI for Detection of Carotid Atheroma in Acute Neurovascular Syndrome. [Journal Article]
- Background MRI and fluorine 18-labeled sodium fluoride (18F-NaF) PET can be used to identify features of plaque instability, rupture, and disease activity, but large studies have not been performed. Purpose To evaluate the association between 18F-NaF activity and culprit carotid plaque in acute neurovascular syndrome. Materials and Methods In this prospective observational cohort study (October 2…
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- Uric Acid Expression in Carotid Atherosclerotic Plaque and Serum Uric Acid Are Associated With Cerebrovascular Events. [Journal Article]
- CONCLUSIONS: The current study supports a potential role of UA as a potential tissue participant and a systemic biomarker in the pathogenesis of carotid atherosclerosis. UA may provide a mechanistic explanation for plaque instability and subsequent ischemic cerebrovascular events.
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- Central retinal artery occlusion and subsequent amaurosis fugax in the contralateral eye associated with the G20210A prothrombin gene (F2) variant: a case report. [Case Reports]Ophthalmic Genet. 2022 10; 43(5):646-652.OG
- CONCLUSIONS: While the G20210A prothrombin gene (F2) variant is a rare cause of retinal artery occlusion, it is important to consider it a differential diagnosis. Good visual outcomes can be achieved with prompt initiation of antithrombotic treatment. In addition, OCT-A is useful for diagnosing ischemic retinal changes that cannot be observed with other diagnostic methods and monitoring them.
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- Posterior Cerebral Artery Stenosis Presenting With Amaurosis Fugax. [Journal Article]J Neuroophthalmol. 2022 Apr 19 [Online ahead of print]JN
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- Carotid Stump Syndrome With Stent-Assisted Coil Embolization. [Case Reports]
- Carotid stump syndrome (CSS) is a rare cause of recurrent ipsilateral cerebrovascular events that typically manifests as transient ischemic attacks or amaurosis fugax. The cause of these recurrent symptoms is thought to be microembolization from an occluded internal carotid artery that reaches intracranial circulation through anastomoses. We undertook a systematic literature review according to P…
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- Amaurosis as an initial presentation of Takayasu arteritis in children. [Review]
- Visual disturbances in Takayasu arteritis (TA) are common but tend to be late manifestations of the disease. However, its presence at diagnosis must alert TA to avoid sight disabilities. Herein, we present two children with TA that debuted with vision loss, and the results of the literature review displayed 58 subjects with vision loss before the diagnosis of TA. The world English literature was …
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- Amaurosis Fugax: A Rare Oxaliplatin-Induced Ocular Toxicity - A Report of Three Cases. [Case Reports]
- Oxaliplatin, a third-generation platinum-based agent, is a constitutive part of systemic treatment for colorectal cancer in adjuvant and metastatic settings. Ocular toxicity is an extremely rare adverse effect of Oxaliplatin. Ocular toxicities have been documented in the form of (a) common (≥1/100, <1/10) which include the conjunctivitis, unexpected lacrimation, blurry vision, blepharoptosis, and…
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- Ischemic ocular manifestations of giant cell arteritis: A Canadian case series. [Journal Article]J Neurol Sci. 2022 05 15; 436:120222.JN
- CONCLUSIONS: Occult GCA occurs more commonly in older patients who most of the time present with AION. Levels of inflammatory markers were similar in the occult and systemic groups. Though ocular ischemic manifestations were similar in both cohorts, in systemic GCA involvement of multiple ocular circulations is likely more common GCA should always be considered in older patients who present with signs of retinal and/or optic nerve head ischemia (AION and/or CWS) and new onset of CNPs, especially in patients where more than one ocular arterial circulation is involved.
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