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Unbound Medicine.
(Americaine)
1,799 results
  • A Case Report of Cyanosis With Refractory Hypoxemia: Is It Methemoglobinemia? [Case Reports]
    Cureus. 2022 Nov; 14(11):e32053.Kamath SD, Sunny S, Upadhyay A
  • Dapsone is used in the treatment of a variety of dermatological conditions and prophylaxis of opportunistic infections. However, if consumed at a dose of more than 200 mg/day, it can cause methemoglobinemia, a condition characterized by elevated methemoglobin levels in the blood; methemoglobin is an abnormal form of hemoglobin, containing iron in the ferric state (Fe3 +) rather than the reduced f…
  • An oligosaccharide marker for rapid authentication of edible bird's nest. [Journal Article]
    Food Chem. 2023 May 30; 409:135334.Li LF, Cheng HY, … Han QB
  • Edible bird's nest (EBN) is a popular and expensive food material. The limited supply and great demand result in the use of adulterants. The authenticity concern is raised due to the lack of appropriate quality markers. Herein, this study aims to provide a specific oligosaccharide marker for rapid EBN authentication. Comparing the benzocaine (ABEE)-labeled saccharide profiles of multiple batches …
  • StatPearls: Benzocaine [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)SinghRavneetRChicago Medical School Rosalind FranklinAl KhaliliYasirYVirginia Commonwealth UniversityBOOK
  • Benzocaine is a local anesthetic used in pain control management, and it is in the ester local anesthetic class of medications. This activity describes the indications, action, and contraindications for benzocaine as a valuable agent in managing pain control. This activity will highlight the mechanism of action, adverse event profile, and other key factors (e.g., off-label uses, dosing, pharmacod…
  • Effects of local anesthetics on compound action potentials generated from the frog sciatic nerve. [Journal Article]
    Adv Physiol Educ. 2022 Dec 01; 46(4):658-666.Medler S
  • The frog sciatic nerve provides a robust physiological preparation students may conveniently use to investigate the properties of compound action potentials. Electrical stimulation with standard physiology teaching equipment elicits compound action potentials that are easily recorded by upper-level undergraduate students. The amplitude of compound action potentials increases with greater stimulat…
  • Reagentless Voltammetric Identification of Cocaine from Complex Powders. [Journal Article]
    Anal Chem. 2022 09 20; 94(37):12638-12644.Vannoy KJ, Krushinski LE, … Dick JE
  • Cocaine is one of the most commonly trafficked and abused drugs in the United States, and deployable field tests are important for rapid identification in nonlaboratory settings. At present, colorimetric tests exist for in-field determination, but these fundamentally suffer from interferent effects. Cocaine is an organic salt that is readily water soluble as a cation and almost insoluble in the d…
  • A Rare Culprit of Methemoglobinemia. [Case Reports]
    J Investig Med High Impact Case Rep. 2022 Jan-Dec; 10:23247096221117919.Fadah K, Rivera M, … Deoker A
  • Methemoglobinemia is a rare cause of hypoxia and can be a diagnostic challenge early in the disease course. The incidence of medication-induced methemoglobinemia is more common than congenital-related methemoglobinemia. The most common cause of methemoglobinemia is exposure to household detergents, illicit drugs, or medications with nitrate or sulfonamide chemical groups. The 2 main medications a…
  • [Allergy Diagnostics 2021]. [Review]
    Laryngorhinootologie. 2022 08; 101(8):673-686.Zieglmayer P
  • Allergic diseases are among the most common diseases worldwide. For appropriate management knowledge of the allergy trigger is crucial. The clinical picture of allergic diseases is diverse and correct diagnosis is often a challenge. The allergist needs to distinguish intolerances from allergies and infectious diseases from non-infectious triggers. Test results have to be interpreted accordingly t…
  • Anaesthesia of decapod crustaceans. [Review]
    Vet Anim Sci. 2022 Jun; 16:100252.de Souza Valente C
  • Decapod crustaceans (crabs, hermit crabs, lobsters, crayfish, shrimps, prawns) are sentient beings, not only responding to noxious stimuli but also being capable of feeling pain, discomfort, and distress. General anaesthesia aims at producing analgesia, immobilization, and unconsciousness, while sedation reduces consciousness, stress, and anxiety, though without analgesia. Anaesthesia is recommen…
  • A Retrospective Study of 23 Cases: Are Lichenoid Lesions of the Labial Mucosa Induced? [Journal Article]
    Cureus. 2022 May; 14(5):e25012.Lehner J, Agbo-Godeau S, Bertolus C
  • Background Lichen planus (LP) is a pathology that affects the skin and the mucosa. The lips are rarely involved but represent a diagnostic challenge in those cases. Oral lichenoid lesions (OLL) are defined as lesions that resemble oral lichen planus (OLP) but do not fully meet the clinical and/or histologic criteria for OLP. This study aimed to present our case series and to study the correlation…
  • Portable Raman spectroscopy applied to the study of drugs of abuse. [Journal Article]
    J Forensic Sci. 2022 Jul; 67(4):1399-1416.Santos LP, Nascimento MHC, … Romão W
  • The use of drugs of abuse has grown significantly in recent decades. In forensic chemistry, methods of identifying and characterizing illicit drugs contribute to the interests of researchers, experts, and public security authorities. Among existing methods, portable Raman spectroscopy is notable for performing rapid, non-destructive, and highly selective analysis in the laboratory or on-site. Whe…
  • Benzocaine-induced methaemoglobinaemia in an adolescent with sepsis. [Case Reports]
    BMJ Case Rep. 2022 Feb 28; 15(2)Jayapal A, Rosario DC, … Ambati S
  • Methaemoglobinaemia is a potentially life-threatening condition characterised by hypoxaemia, cyanosis, pallor, fatigue, metabolic acidosis, headache and in severe cases, coma or death. Topical anaesthetics have been reported to cause methaemoglobinaemia. Topical benzocaine was specifically implicated in roughly 66% of anesthetic-induced methaemoglobinaemia cases in a large systematic review in ad…
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