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Unbound Medicine.
(Amphetamine & cocaine overdose)
211 results
  • Associations between prescription and illicit stimulant and opioid use in the United States, 2015-2020. [Journal Article]
    J Subst Abuse Treat. 2022 12; 143:108894.Shearer RD, Jones A, … Winkelman TNA
  • CONCLUSIONS: Prescription stimulant misuse, compared to prescription opioid misuse, was associated with higher levels of cocaine use but not methamphetamine use. Treatment providers should consider screening for other substance use disorders among people who report prescription stimulant use or misuse. Additional research should seek to understand the mechanism underlying the different associations between prescription stimulant misuse and cocaine or methamphetamine use.
  • Stimulant misuse among youth. [Review]
    Curr Probl Pediatr Adolesc Health Care. 2022 09; 52(9):101265.LaBossier NJ, Hadland SE
  • Rates of stimulant use, including misuse of prescription stimulants and use of cocaine and methamphetamine, are rising rapidly among adolescents and young adults ("youth"). Stimulant misuse is associated with overdose, polysubstance use, substance use disorders, and other medical harms. Substance use is often initiated during adolescence and young adulthood, and interventions during these crucial…
  • Early-Onset Cardiovascular Disease From Cocaine, Amphetamines, Alcohol, and Marijuana. [Review]
    Can J Cardiol. 2022 09; 38(9):1342-1351.O'Keefe EL, Dhore-Patil A, Lavie CJ
  • Cardiovascular disease (CVD), a disease typically associated with aging and the definitive leading cause of death worldwide, now threatens young and middle-aged populations. Recreational abuse of alcohol, marijuana, cocaine, and amphetamine-type stimulants has been an escalating public health problem for decades, but now use of these substances has become a significant contributor to early-onset …
  • Trends in characteristics of fentanyl-related poisonings in the United States, 2015-2021. [Journal Article]
    Am J Drug Alcohol Abuse. 2022 07 04; 48(4):471-480.Palamar JJ, Cottler LB, … Ciccarone D
  • Background: Fentanyl-related deaths continue to increase in the United States; however, most national studies focus on fatal overdose. More research, including data on nonfatal overdose, is needed.Objective: We examined trends in characteristics of fatal and nonfatal fentanyl-related poisonings ("exposures") in the US.Methods: National Poison Control data were examined to estimate trends in chara…
  • Human behavioral pharmacology of stimulant drugs: An update and narrative review. [Review]
    Adv Pharmacol. 2022; 93:77-103.Strzelecki A, Weafer J, Stoops WW
  • Stimulant use disorders present an enduring public health concern. Chronic stimulant use is associated with a range of health problems, with notable increases in stimulant overdose that disproportionately affect marginalized populations. With these persistent problems, it is important to understand the behavioral and pharmacological factors that contribute to stimulant use in humans. The purpose …
  • Substance abuse and neurotransmission. [Journal Article]
    Adv Pharmacol. 2022; 93:403-441.Davis S, Zhu J
  • The number of people who suffer from a substance abuse disorder has continued to rise over the last decade; particularly, the number of drug-related overdose deaths has sharply increased during the COVID-19 pandemic. Converging lines of clinical observations, supported by imaging and neuropsychological performance testing, have demonstrated that substance abuse-induced dysregulation of neurotrans…
  • Interactions between opioids and stimulants: Behavioral pharmacology of abuse-related effects. [Journal Article]
    Adv Pharmacol. 2022; 93:1-33.Maguire DR, Minervini V
  • Opioid abuse continues to be a significant public health challenge, with rates of opioid-related overdose deaths increasing continuously over the last two decades. There also has been a sharp increase in overdose deaths involving stimulant drugs, primarily cocaine and methamphetamine. Recent estimates indicate a high prevalence of co-use of opioids and stimulants, which is a particularly complex …
  • Stimulant Drugs of Abuse and Cardiac Arrhythmias. [Review]
    Circ Arrhythm Electrophysiol. 2022 01; 15(1):e010273.Dominic P, Ahmad J, … Olshansky B
  • Nonmedical use of prescription and nonprescription drugs is a worldwide epidemic, rapidly growing in magnitude with deaths because of overdose and chronic use. A vast majority of these drugs are stimulants that have various effects on the cardiovascular system including the cardiac rhythm. Drugs, like cocaine and methamphetamine, have measured effects on the conduction system and through several …
  • Understanding Stimulant Use and Use Disorders in a New Era. [Review]
    Med Clin North Am. 2022 Jan; 106(1):81-97.Ciccarone D, Shoptaw S
  • Extending from the triple wave epidemic of opioid-related overdose deaths, a fourth wave of high mortality involving methamphetamine and cocaine use has been gathering force. This article provides a review of the published literature on stimulants including epidemiology, pharmacology, neurobiology, medical and psychiatric consequences, withdrawal management, and medical and behavioral treatments.
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