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Unbound Medicine.
(Ampullary carcinoma of small intestine)
1,032 results
  • Adenocarcinoma of the Ampulla of Vater: A Case Report on a Rare Condition. [Case Reports]
    Cureus. 2022 Sep; 14(9):e29398.Kantode VV, Sharma R, … Nakhale A
  • An ampullary carcinoma (AC) is defined as cancer that arises in the ampulla of Vater (AV). It is a tiny opening in the beginning segment of the small intestine called the duodenum. Pancreatic and bile duct fluids are pumped into the intestines via the AV. There are various factors listed as the causes of AC. A 45-year-old male presented to the emergency department with complaints of pain in the a…
  • A rare case of long-term survival of a patient who underwent radical operations for sextuple malignancies. [Case Reports]
    Clin J Gastroenterol. 2022 Dec; 15(6):1169-1172.Nanashima A, Imamura N, … Tsuchimochi Y
  • Multiple cancer patients who achieve long-term survival are sometimes encountered. Multiple carcinogenesis may occur due to genetic or environmental characteristics. We report the case of a 74-year-old woman who was diagnosed with synchronous double carcinoma of the duodenal papilla and gall bladder without clinical symptoms, who underwent postoperative follow-up for familiar adenomatous polyposi…
  • Personal comorbidities and their subsequent risks for liver, gallbladder and bile duct cancers. [Journal Article]
    Int J Cancer. 2023 Mar 15; 152(6):1107-1114.Hemminki K, Sundquist K, … Li X
  • Many environmental risk factors for hepatobiliary cancers are known but whether they are associated with specific cancer types is unclear. We present here a novel approach of assessing standardized incidence ratios (SIRs) of previously diagnosed comorbidities for hepatocellular carcinoma (HCC), gallbladder cancer (GBC), cholangiocarcinoma (CCA) and ampullary cancer. The 13 comorbidities included …
  • Controversies in the diagnosis and treatment of periampullary tumours. [Review]
    Surg Oncol. 2022 Sep; 44:101853.Skórzewska M, Kurzawa P, … Polkowski WP
  • Most tumours in the head of the pancreas are adenocarcinomas of the exocrine pancreas. However, carcinomas located in the head of the pancreas may originate from the papilla of Vater, the distal part of the common bile duct, or the duodenum. Tumours of that region, within 2 cm of the greater duodenal papilla, have been usually described as periampullary neoplasms. Adenocarcinomas separated from t…
  • Endoscopic therapy of sporadic non-ampullary duodenal adenomas, single centre retrospective analysis. [Journal Article]
    Scand J Gastroenterol. 2023 Feb; 58(2):208-215.Udd M, Lindström O, … Kylänpää L
  • CONCLUSIONS: Endotherapy of SNADA is effective and safe. Repeat endotherapy in residual and recurrent adenomas is successful. Careful patient selection is mandatory. Abbreviations: ASA: American Society of Anesthesiologist classification; BMI: body mass index; CT: computed tomography; EBL: endoscopic band ligation; EMR: endoscopic mucosal resection; ESD: endoscopic submucosal dissection; ET: endotherapy; FAP: familial adenomatous polyposis; F: female; LST: laterally spreading tumours; M: male; SD: standard deviation; SNADA: sporadic nonampullary duodenal adenoma.
  • Claudin-18 expression in small bowel adenocarcinoma: a clinico-pathologic study. [Journal Article]
    Virchows Arch. 2022 Dec; 481(6):853-863.Arpa G, Fassan M, … Vanoli A
  • Non-ampullary small bowel adenocarcinoma is a rare neoplasm with an ominous prognosis, whose incidence is higher in some chronic immuno-inflammatory conditions, such as coeliac and Crohn's disease. Recently, claudin 18.2, a transmembrane protein normally expressed in gastric mucosa, has been recognized as a novel pan-cancer therapeutic target, and several clinical trials with claudin-18-directed …
  • [Contrastive study on MRI signs of intestinal and pancreatobiliary-type periampullary carcinoma]. [Journal Article]
    Zhonghua Yi Xue Za Zhi. 2022 May 17; 102(18):1351-1358.Zhu QJ, He J, … Yan CC
  • Objective: The magnetic resonance imaging (MRI) features of intestinal-type periampullary carcinoma (IPAC) and pancreatobiliary-type periampullary carcinoma (PPAC) were compared and analyzed to discuss the optimal diagnosis scheme. Method: Preoperative MRI images of 59 patients (32 males, 27 females, aged 37-80 years) diagnosed with periampullary carcinoma (PAC) confirmed by surgery and pathology…
  • Safety and Efficacy of Avelumab in Small Bowel Adenocarcinoma. [Journal Article]
    Clin Colorectal Cancer. 2022 09; 21(3):236-243.Cardin DB, Gilbert J, … Berlin J
  • CONCLUSIONS: Despite the observed benefit, accrual was slower than expected and the study was closed early due to feasibility. A general clinic observation was that patients were receiving immunotherapy off-label as the availability of these agents increased. Off-label availability and disease rarity were likely drivers of insufficient accrual.
  • [Ampullary Carcinoma-prognostic and Therapeutical Contrast to Pancreatic Ductal Adenocarcinoma]. [Journal Article]
    Zentralbl Chir. 2022 Apr; 147(2):160-167.Giehl-Brown E, Weitz J, Distler M
  • Ampullary carcinoma belongs to the cluster of periampullary cancers and is a rare, but increasing form of gastrointestinal malignancy. Due to the location of the tumour, occurrence of biliary obstruction is common. Symptoms due to the compression of the biliary tract facilitate early diagnosis, evoking a better prognosis. Adenomas of the ampulla of Vater and major duodenal papilla are precursor l…
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