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Unbound Medicine.
(Anal cancer)
25,900 results
  • [Laparoscopic Abdominoperineal Resection for Anal Canal Cancer with Pagetoid Spread]. [Journal Article]
    Gan To Kagaku Ryoho. 2022 Dec; 49(13):1455-1457.Bamba Y, Nakano M, … Wakai T
  • A woman in her 60s had been aware of perianal erosions for 1 month. Skin biopsy showed Paget's cells in the stratified squamous epithelium, and immunohistochemistry showed negative staining for CK7 and positive staining for CK20. Colonoscopy revealed well-differentiated adenocarcinoma in the anal canal. Computed tomography showed neither regional lymph node metastasis nor distant metastasis. Henc…
  • Poly(ethylene oxide) Concentration Gradient-Based Microfluidic Isolation of Circulating Tumor Cells. [Journal Article]
    Anal Chem. 2023 Feb 01 [Online ahead of print]Cheng Y, Zhang S, … Liu C
  • Circulating tumor cells (CTCs) have emerged as promising circulating biomarkers for non-invasive cancer diagnosis and management. Isolation and detection of CTCs in clinical samples are challenging due to the extreme rarity and high heterogeneity of CTCs. Here, we describe a poly(ethylene oxide) (PEO) concentration gradient-based microfluidic method for rapid, label-free, highly efficient isolati…
  • Continual learning strategies for cancer-independent detection of lymph node metastases. [Journal Article]
    Med Image Anal. 2023 Jan 25; 85:102755.Bándi P, Balkenhol M, … Litjens G
  • Recently, large, high-quality public datasets have led to the development of convolutional neural networks that can detect lymph node metastases of breast cancer at the level of expert pathologists. Many cancers, regardless of the site of origin, can metastasize to lymph nodes. However, collecting and annotating high-volume, high-quality datasets for every cancer type is challenging. In this pape…
  • ASAP─Automated Sonication-Free Acid-Assisted Proteomes─from Cells and FFPE Tissues. [Journal Article]
    Anal Chem. 2023 Feb 01 [Online ahead of print]Barnabas GD, Goebeler V, … Lange PF
  • Formalin-fixed, paraffin-embedded (FFPE) tissues are an invaluable resource for retrospective studies, but protein extraction and subsequent sample processing steps have been shown to be challenging for mass spectrometry (MS) analysis. Streamlined high-throughput sample preparation workflows are essential for efficient peptide extraction from complex clinical specimens such as fresh frozen tissue…
  • Transanal minimally invasive surgery - A single-center experience. [Journal Article]
    J Minim Access Surg. 2023 Jan-Mar; 19(1):35-41.Pangeni A, Imtiaz MR, … Basnyat PS
  • CONCLUSIONS: Our data suggest that TAMIS can be safely performed in a district general hospital for both benign and early rectal cancer. TAMIS was also able to control post-polypectomy bleeding and completion of rectal polypectomy. In selected cases, day-case TAMIS is safe and feasible.
  • Patenting trends in the pharmaceutical field of Mexican universities. [Journal Article]
    Pharm Pat Anal. 2023 Feb 01 [Online ahead of print]Sanchez-Esgua G, Reyes-Alvarez J, Perez-Santos M
  • Aim: pharmaceutical patenting activity in developing countries, including Mexico, is unknown. Objective: determine the activity of pharmaceutical patents by Mexican universities. Method: using 'university' as keyword and A61K, A61P and C07 as International Patent Classification codes, was searched to generate a perspective of pharmaceutical patent applications by Mexican universities. Results: 22…
  • Chemiluminescence Sensor for miRNA-21 Detection Based on CRISPR-Cas12a and Cation Exchange Reaction. [Journal Article]
    Anal Chem. 2023 Jan 30 [Online ahead of print]Zhou Y, Xie S, … Zhang S
  • Herein, a chemiluminescence (CL) biosensor based on CRISPR-Cas12a and cation exchange reaction was constructed to detect the biomarker microRNA-21 (miRNA-21). The rolling circle amplification (RCA) reaction was introduced to convert each target RNA strand into a long single-stranded DNA with repeated sequences, which acted as triggers to initiate the transcleavage activity of CRISPR-Cas12a. The a…
  • FMNL2 promotes angiogenesis and metastasis of colorectal cancer by regulating EGFL6/CKAP4/ERK axis. [Journal Article]
    Cancer Sci. 2023 Jan 30 [Online ahead of print]He G, Li W, … Liang L
  • Increasing evidence indicates that angiogenesis plays a pivotal role in tumor progression. Formin-like 2 (FMNL2) is well-known for promoting metastasis; however, the molecular mechanisms by which FMNL2 promotes angiogenesis in colorectal cancer (CRC) remain unclear. Here, we found that FMNL2 promotes angiogenesis and metastasis of CRC in vitro and in vivo. The GDB/FH3 domain of FMNL2 directly int…
  • [Infection of human papillomavirus and head and neck cancer]. [Review]
    Zhonghua Zhong Liu Za Zhi. 2023 Jan 23; 45(1):39-43.Song C, Zhang SK, Qiao YL
  • High-risk human papillomavirus (HPV)-related cancers consist of cervical cancer, anal cancer, penile cancer, vulvar cancer, vaginal cancer, and head and neck cancer (HNC). Of these, the disease burden of HNC is second only to cervical cancer. HNC mostly originates from malignant lesions of squamous epithelial cells and mainly includes oral cavity cancer, pharyngeal cancer (including nasopharyngea…
  • The HoloLens in medicine: A systematic review and taxonomy. [Journal Article]
    Med Image Anal. 2023 Jan 21; 85:102757.Gsaxner C, Li J, … Egger J
  • The HoloLens (Microsoft Corp., Redmond, WA), a head-worn, optically see-through augmented reality (AR) display, is the main player in the recent boost in medical AR research. In this systematic review, we provide a comprehensive overview of the usage of the first-generation HoloLens within the medical domain, from its release in March 2016, until the year of 2021. We identified 217 relevant publi…
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