- Trends and variation in pediatric anaphylaxis care from 2016-2022. [Journal Article]J Allergy Clin Immunol Pract. 2023 Feb 01 [Online ahead of print]JA
- CONCLUSIONS: ED visits for anaphylaxis increased during the study period, but hospitalization rates were low. Substantial variation exists between EDs regarding the use of anaphylaxis therapies, supporting the need for future research to evaluate the efficacy of these medications.
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- Kounis Syndrome Associated With the Use of Diclofenac. [Journal Article]Tex Heart Inst J. 2023 Jan 01; 50(1)TH
- CONCLUSIONS: Clinicians should be aware that Kounis syndrome may be an adverse effect of diclofenac. Prompt recognition and withdrawal of the drug, with treatment of both allergic and cardiac symptoms simultaneously, is important.
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- A case report of gadopentetate dimeglumine-induced cardiac arrest: Resuscitation using extracorporeal membrane oxygenation. [Case Reports]Ann Noninvasive Electrocardiol. 2023 Feb 03 [Online ahead of print]AN
- Gadopentetate dimeglumine (Gd-DTPA) is commonly used for enhancement in magnetic resonance imaging, but rarely causes serious adverse reactions. The patient presented in this report had a cardiac arrest and multiple organ dysfunction syndrome within a short time after administration of Gd-DTPA. Immediately after receiving an intravenous injection of Gd-DTPA, the patient felt nausea and chest tigh…
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- Factors increasing mortality in Echinococcosis patients treated percutaneously or surgically. A review of 1,143 patients: a retrospective single center study. [Journal Article]Eur Rev Med Pharmacol Sci. 2023 Jan; 27(2):493-500.ER
- CONCLUSIONS: CE is a disease that can occur at any age and can be fatal. Although multi-organ involvement and percutaneous treatment may be associated with recurrence, they do not directly increase mortality. The mortality is high, especially in pregnant women with pulmonary CE. Cardiac involvement, brain involvement and anaphylaxis increase mortality. Mortality is higher in patients without follow-up who are operated on urgently.
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- Peach extract induces systemic and local immune responses in an experimental food allergy model. [Journal Article]Sci Rep. 2023 Feb 02; 13(1):1892.SR
- Peach allergy is among the most frequent food allergies in the Mediterranean area, often eliciting severe anaphylactic reactions in patients. Due to the risk of severe symptoms, studies in humans are limited, leading to a lack of therapeutic options. This study aimed to develop a peach allergy mouse model as a tool to better understand the pathomechanism and to allow preclinical investigations on…
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- Updates in diagnosis and management of paediatric mastocytosis. [Journal Article]Curr Opin Allergy Clin Immunol. 2022 Nov 03 [Online ahead of print]CO
- CONCLUSIONS: Morbidity in paediatric mastocytosis typically arises from symptoms secondary to mast cell mediator release. Prognosis for nonaggressive disease is typically favourable; however, risks for anaphylaxis and psychosocial morbidity may be underestimated. Symptomatic management and anticipatory guidance may help support patients and families throughout the disease course.
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- The Onset of Food-dependent Exercise-induced Anaphylaxis in an Elderly Patient: A Case Report. [Journal Article]Intern Med. 2023 Feb 01 [Online ahead of print]IM
- The development of allergic diseases is common in the young but rare in the elderly. We encountered an elderly patient with food-dependent exercise-induced anaphylaxis (FDEIA). An 82-year-old man was rushed to the hospital for symptoms of anaphylaxis. Because the symptoms occurred after ingestion of wheat products and exercise, we made a diagnosis of FDEIA based on a high ω5-gliadin IgE level and…
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- Ocrelizumab in pediatric multiple sclerosis. [Journal Article]Eur J Paediatr Neurol. 2023 Jan 27; 43:1-5.EJ
- CONCLUSIONS: Ocrelizumab can be considered a safe and effective treatment option in highly active P-RRMS.
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- Sialylation of IgE reduces FcεRIα interaction and mast cell and basophil activation in vitro and increases IgE half-life in vivo. [Letter]Allergy. 2023 Feb 01 [Online ahead of print]A
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- An update on remimazolam and anaphylaxis. [Journal Article]Eur J Anaesthesiol. 2023 Mar 01; 40(3):153-154.EJ
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- S3 Guideline Urticaria. Part 1: Classification and diagnosis of urticaria - German-language adaptation of the international S3 Guideline. [Journal Article]J Dtsch Dermatol Ges. 2023 01; 21(1):81-93.JD
- The lifetime prevalence of urticaria, a severe allergic disease, is almost 20%. It not only limits the quality of life of those affected, but also their general performance at work and in their daily activities. This publication is the first section of the Urticaria Guideline. It covers the classification and diagnosis of urticaria, taking into account the major advances in research into its caus…
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- Anaphylaxis Following Contrast-Enhanced CT with Iodixanol: A Case Report and Literature Review. [Case Reports]
- CONCLUSIONS: A 47-year-old female patient with no history of allergies developed severe fatal anaphylactic shock after receiving iodixanol. Although contrast agents induced anaphylactoid/anaphylactic reactions do not often occur, clinicians should be conscious of the potentially serious anaphylactic reaction, which could lead to a life-threatening or fatal event.
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- Variation in diagnosis and management of allergic reactions among emergency medicine and allergy immunology providers. [Journal Article]Allergy Asthma Proc. 2023 Jan 01; 44(1):51-58.AA
- Background: Children with anaphylaxis often emergently present for treatment. Providers' adherence to the principles of optimal management according to the most recent national guidelines is unknown. Objective: To assess the variation in management approaches for allergic reactions and anaphylaxis between allergy/immunology (AI) and emergency medicine (EM) providers. Methods: This was a cross-sec…
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- Peanut allergy in an adult following cardiac transplant from a non-atopic donor. [Case Reports]Allergy Asthma Proc. 2023 Jan 01; 44(1):81-84.AA
- We present a 62-year-old woman with severe heart failure and who required cardiac transplantation. On postoperative day 22, she experienced anaphylaxis to peanut, with an elevated peanut-specific immunoglobulin E level. This case highlights the differential diagnosis of posttransplantation anaphylaxis as well as the appropriate evaluation.
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- Epinephrine autoinjectors: individualizing device and dosage to optimize anaphylaxis management in the community setting. [Journal Article]Allergy Asthma Proc. 2023 Jan 01; 44(1):45-50.AA
- Background: Anaphylaxis is the most severe manifestation of a systemic allergic reaction, and, in the community setting, the immediate administration of an epinephrine autoinjector (EAI) can be life-saving. Physicians are tasked with selecting the most appropriate EAI for each individual and counseling patients and/or their caregivers to maximize the likelihood of successful deployment of the EAI…
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- Anaphylaxis: Long-term management and resources. [Review]Allergy Asthma Proc. 2023 Jan 01; 44(1):35-44.AA
- Background: Anaphylaxis is an acute life-threatening event that requires emergent diagnosis and treatment. However, focus on prevention of anaphylaxis is essential in reducing anaphylaxis recurrences and associated mortality. Objective: This literature review was aimed to be a comprehensive resource for practicing allergists in managing anaphylaxis in the long term. We discussed the role of the a…
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- The Need for Required Stock Epinephrine in All Schools: A Work Group Report of the AAAAI Adverse Reactions to Foods Committee. [Journal Article]J Allergy Clin Immunol Pract. 2023 Jan 27 [Online ahead of print]JA
- Epinephrine is the first line of treatment for anaphylaxis which can occur outside a medical setting in community environments like schools. Patients with diagnosed IgE-mediated food allergy at risk of anaphylaxis are prescribed self-injectable epinephrine and given an individualized anaphylaxis action plan. As students, such patients/families provide their school with completed medication forms,…
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- Evaluating the Food Allergy Passport: A Novel Food Allergy Clinical Support Tool. [Journal Article]J Allergy Clin Immunol Pract. 2023 Jan 27 [Online ahead of print]JA
- CONCLUSIONS: The FA Passport is a novel FA clinical support tool that helps address barriers to proper FA management described in previous studies. It proved effective at improving caregiver comfort with their food-allergic children with other caregivers, increasing FA knowledge, and improving the quality of life in families affected by FA.
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- Do Children With an Allergic Transfusion Reaction Require Premedication or All Blood Products? [Journal Article]J Pediatr Hematol Oncol. 2023 Jan 23 [Online ahead of print]JP
- CONCLUSIONS: In children with a history of ATR, developing a reaction to a different blood product type is rare. Hence, premedicating those transfusions is not warranted.
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- Simulation-based education to improve management of refractory anaphylaxis in an allergy clinic. [Journal Article]
- CONCLUSIONS: High-fidelity simulations can improve the management of anaphylaxis in the allergy clinic and team confidence. This activity was instrumental in reducing staff reluctance to perform high-risk challenges in the ambulatory setting, thus lifting a critical barrier for implementing oral immunotherapy at our adult center.
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- Gymnadenia conopsea (L.) R. Br.: Comprehensive review of propagation and breeding, traditional uses, chemical composition, pharmacology, quality control, and processing. [Review]J Ethnopharmacol. 2023 Jan 25; 306:116205.JE
- CONCLUSIONS: The chemical constituents and pharmacological activities studies of G. conopsea extract have been summarised in this context, the isolated compounds responsible for the pharmacological activities were also analyzed and deduced according to the publications, all above led to suggestions for the future high-value utilization of G. conopsea.
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- Rate of Patch Testing Induced Anaphylaxis. [Review]Dermatitis. 2023 Jan-Feb; 34(1):33-35.D
- Background: Although allergic contact dermatitis is a type IV hypersensitivity reaction, type I hypersensitivity reactions, such as anaphylaxis, have been reported during patch testing. Objective: The aim of this study was to identify reported cases of anaphylaxis from patch testing and estimate its rate. Methods: A literature review was conducted on PubMed to identify previously reported cases o…
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- Digitally-enabled, patient-centred care in rhinitis and asthma multimorbidity: The ARIA-MASK-air® approach. [Journal Article]
- MASK-air® , a validated mHealth app (Medical Device regulation Class IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK-air® is a Good Practice of DG Santé on digitally-enabled, patient-centred care. It is also a candidate Good Practice of OECD (Organis…
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- Multiple Wasp Stings Leading to Rhabdomyolysis Induced Acute Kidney Injury with Incidental Ectopic Kidney: A Case Report. [Case Reports]JNMA J Nepal Med Assoc. 2022 Oct 01; 60(254):898-901.JJ
- Rhabdomyolysis refers to skeletal muscle breakdown causing a release of different intracellular proteins including myoglobin and several electrolytes in the bloodstream. Elevations diagnose rhabdomyolysis in serum creatine kinase. Mass envenomation by multiple wasp stings can cause rhabdomyolysis followed by acute kidney injury, although it is scarce. A 24-year-old male presented to our tertiary …
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- Pathogenesis, immunology, and immune-targeted management of the multisystem inflammatory syndrome in children (MIS-C) or pediatric inflammatory multisystem syndrome (PIMS): EAACI Position Paper. [Journal Article]Pediatr Allergy Immunol. 2023 Jan; 34(1):e13900.PA
- Multisystem inflammatory syndrome in children (MIS-C) is a rare, but severe complication of coronavirus disease 2019 (COVID-19). It develops approximately 4 weeks after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and involves hyperinflammation with multisystem injury, commonly progressing to shock. The exact pathomechanism of MIS-C is not known, but immunological dysreg…
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- Preliminary pilot study results of the EAACI allergy educational needs in primary care pediatricians Task Force in managing allergic disorders. [Letter]Pediatr Allergy Immunol. 2023 Jan; 34(1):e13907.PA
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- Targeting Ara h 2 with human-derived monoclonal antibodies prevents peanut-induced anaphylaxis in mice. [Journal Article]Allergy. 2023 Jan 27 [Online ahead of print]A
- CONCLUSIONS: This is the first report that shows that human-derived anti-peanut mAbs can prevent allergic anaphylaxis in mice. The study demonstrates that neutralising allergenic epitopes on Ara h 2 by mAbs may represent a promising treatment option in peanut-allergy.
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- A Case of Tooth Extraction in a Patient with Food-Dependent Exercise Induced Anaphylaxis. [Case Reports]
- A 29-year-old Japanese man with food-dependent exercise-induced anaphylaxis (FDEIA) underwent tooth extraction under general anesthesia. FDEIA is a rare condition in which anaphylaxis occurs due to exercise load or oral administration of NSAIDs after ingestion of allergens. Wheat is often the cause in FEDIA, defined as wheat-dependent exercise-induced anaphylaxis (WDEIA). It is an allergy that is…
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- [Acute management of anaphylaxis]. [Journal Article]MMW Fortschr Med. 2023 02; 165(2):48-55.MF
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