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Unbound Medicine.
(Anaplastic thyroid carcinoma)
3,708 results
  • Anaplastic Cancer: Our Experience. [Journal Article]
    Indian J Surg Oncol. 2022 Dec; 13(4):789-796.Kanteti APK, Ghose J, … Prabhash K
  • Anaplastic thyroid carcinoma (ATC) is a rare thyroid malignancy with a dire prognosis, nearly 100% disease specific mortality and a median overall survival less than 6 months. In view of the limited data from India on anaplastic thyroid cancer, we conducted this audit to analyze the treatment pattern, outcomes and factors influencing it. This is a retrospective analysis of outcomes of patients tr…
  • The Landscape of Single Nucleotide Polymorphisms in Papillary Thyroid Carcinoma. [Review]
    Cancer Diagn Progn. 2023 Jan-Feb; 3(1):26-30.Kyrodimos E, Chrysovergis A, … Papanikolaou V
  • Thyroid carcinoma represents a leading malignancy among those derived from human endocrine systems. It comprises a variety of different histological subtypes, including mainly papillary carcinoma, follicular carcinoma, anaplastic carcinoma, and medullar carcinoma. A broad spectrum of genetic imbalances, comprising gross chromosomal (polysomy/aneuploidy) and specific gene (mutations, amplification…
  • Targeted Therapy for Anaplastic Thyroid Carcinoma: Advances and Management. [Review]
    Cancers (Basel). 2022 Dec 28; 15(1)Yuan J, Guo Y
  • Anaplastic thyroid carcinoma (ATC) is a rare and highly fatal cancer with the worst prognosis of all thyroid carcinoma (TC) histological subtypes and no standard treatment. In recent years, the explosion of investigations on ATC-targeted agents has provided a new treatment strategy for this malignant condition, and a review of these studies is warranted. We conducted a comprehensive literature se…
  • Refractory Checkpoint Inhibitor Colitis Responsive to Ustekinumab. [Case Reports]
    ACG Case Rep J. 2022 Dec; 9(12):e00946.Perez Del Nogal G, Patel N
  • Immune checkpoint inhibitors have transformed the treatment of cancer. Nonetheless, multiple immune-related adverse events have been reported, including checkpoint inhibitor colitis. Severe colitis can be complicated by ileus, megacolon, intestinal perforation, and death. Current appropriate treatment includes steroids, followed by antitumor necrosis factor biologic therapy, infliximab. Alternati…
  • Ouabain Effects on Human Anaplastic Thyroid Carcinoma 8505C Cells. [Journal Article]
    Cancers (Basel). 2022 Dec 14; 14(24)Teixeira MP, Haddad NF, … de Paiva LS
  • Anaplastic thyroid carcinoma (ATC) is a rare, but aggressive, carcinoma derived from follicular cells. While conventional treatments may improve patients' survival, the lethality remains high. Therefore, there is an urgent need for more effective ATC treatments. Cardiotonic steroids, such as ouabain, have been shown to have therapeutic potential in cancer treatment. Thus, we aimed to evaluate oua…
  • Lipid-Peptide-mRNA Nanoparticles Augment Radioiodine Uptake in Anaplastic Thyroid Cancer. [Journal Article]
    Adv Sci (Weinh). 2023 Jan; 10(3):e2204334.Li Q, Zhang L, … Ge M
  • Restoring sodium iodide symporter (NIS) expression and function remains a major challenge for radioiodine therapy in anaplastic thyroid cancer (ATC). For more efficient delivery of messenger RNA (mRNA) to manipulate protein expression, a lipid-peptide-mRNA (LPm) nanoparticle (NP) is developed. The LPm NP is prepared by using amphiphilic peptides to assemble a peptide core and which is then coated…
  • The 2022 WHO classification of thyroid tumors: novel concepts in nomenclature and grading. [Review]
    Endocr Relat Cancer. 2023 Feb 01; 30(2)Christofer Juhlin C, Mete O, Baloch ZW
  • The fifth edition of the Classification of Endocrine and Neuroendocrine Tumors has been released by the World Health Organization. This timely publication integrates several changes to the nomenclature of non-neoplastic and neoplastic thyroid diseases, as well as novel concepts that are essential for patient management. The heterogeneous group of non-neoplastic and benign neoplastic lesions are n…
  • StatPearls: Follicular Thyroid Cancer [BOOK]
    StatPearls. StatPearls Publishing: Treasure Island (FL)AshorobiDamilolaDNassau University Medical CenterLopezPeter P.PPMSUBOOK
  • The thyroid is an endocrine gland located just below the cricoid cartilage in the neck, and it is composed of both the right and the left lobes separated by an isthmus. The thyroid gland functions to produce the thyroid hormone which is needed by the body to carry out different metabolism. Follicles comprise the thyroid and are the functional and structural units of the gland. Epithelial cells li…
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