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5,097,550 results
  • Focus on the essentials: tryptophan metabolism and the microbiome-gut-brain axis. [Review]
    Curr Opin Pharmacol 2019; 48:137-145Gheorghe CE, Martin JA, … Clarke G
  • The gut-brain axis is a bidirectional communication system between the central nervous system and the gastrointestinal tract, in which serotonin (5-HT) functions as a key neurotransmitter. Recent research has increasingly concentrated on tryptophan, the precursor to 5-HT and on the microbial regulation of tryptophan metabolism, with an emphasis on host-microbe control over kynurenine pathway meta…
  • A review on multiplatform evaluations of semi-automatic open-source based image segmentation for cranio-maxillofacial surgery. [Review]
    Comput Methods Programs Biomed 2019; 182:105102Wallner J, Schwaiger M, … Egger J
  • CONCLUSIONS: High quality image-based semi-automatic segmentation was provided by the GrowCut and the Canny segmentation method. In the cranio-maxillofacial complex, these segmentation methods provide algorithmic alternatives for image-based segmentation in the clinical practice for e.g. surgical planning or visualization of treatment results and offer advantages through their open-source availability. This is the first systematic multi-platform comparison that evaluates multiple license-free, open-source segmentation methods based on clinical data for the improvement of algorithms and a potential clinical use in patient-individualized medicine. The results presented are reproducible by others and can be used for clinical and research purposes.
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