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110,861 results
  • Potential mechanisms linking high-volume exercise with coronary artery calcification. [Review]
    Heart. 2023 Jan 26 [Online ahead of print]Zambrano A, Tintut Y, … Hsu JJ
  • Recent studies have found an association between high volumes of physical activity and increased levels of coronary artery calcification (CAC) among older male endurance athletes, yet the underlying mechanisms have remained largely elusive. Potential mechanisms include greater exposure to inflammatory cytokines, reactive oxygen species and oxidised low-density lipoproteins, as acute strenuous phy…
  • Hormonal abnormalities in alexithymia. [Journal Article]
    Front Psychiatry. 2022; 13:1070066.Goerlich KS, Votinov M
  • Alexithymia is a personality trait characterized by difficulties in emotion recognition and regulation that is associated with deficits in social cognition. High alexithymia levels are considered a transdiagnostic risk factor for a range of psychiatric and medical conditions, including depression, anxiety, and autism. Hormones are known to affect social-emotional cognition and behavior in humans,…
    Acta Endocrinol (Buchar). 2022 Jul-Sep; 18(3):398-400.Chen Y, Zhao M, … Yao H
  • We reported that in a 29-year-old male patient with hyperthyroidism, bilateral breast swelling appeared in three days after starting methimazole and gradually aggravated. Several days later, a small amount of transparent liquid could be squeezed out from bilateral mammary glands. Breast ultrasound confirmed gynaecomastia. The level of testosterone, estradiol and luteinizing hormone increased. Aft…
  • Citrinin inhibits the function of Leydig cells in male rats in prepuberty. [Journal Article]
    Ecotoxicol Environ Saf. 2023 Jan 23; 252:114568.Li X, Tian L, … Wang Y
  • Citrinin, a mycotoxin existing in fruits, has nephrotoxicity, hepatotoxicity and embryotoxicity. The effects of citrinin on Leydig cell development in prepuberty remains unclear. Male Sprague-Dawley rats were gavaged with 0, 1, 2.5, and 5 mg/kg citrinin from postnatal days 21-28. Citrinin at 5 mg/kg significantly decreased serum testosterone levels, while increasing serum LH and FSH levels. Citri…
  • Testosterone Replacement Therapy: A Narrative Review with a Focus on New Oral Formulations. [Review]
    touchREV Endocrinol. 2022 Nov; 18(2):133-140.Bhat SZ, Dobs AS
  • Male hypogonadism affects 10-30% of the male population and is often under-recognized and under-treated. Different replacement formulations exist, each with specific benefits and limitations. These replacements include gels, patches and short- and long-acting injectables. JATENZO® (oral testosterone undecanoate; Clarus Therapeutics Inc., Northbrook, IL, US) is the first oral formulation of testos…
  • A Comparative Clinical and Laboratory Study of Adolescent and Adult Acne in Iraqi Women. [Journal Article]
    Cureus. 2022 Dec; 14(12):e32866.Dhaher SA, Hamdan A, Alyasin ZT
  • Background Acne vulgaris is a common chronic inflammatory disease of the pilosebaceous units associated with long-term sequelae and complications. Currently, acne in women is classified into adolescent and post-adolescent forms. However, comparative studies evaluating the clinical and laboratory parameters across various age groups in women with acne are lacking. The aim of the study is to compar…
  • Risk of Central Serous Chorioretinopathy in Male Androgen Abusers. [Journal Article]
    Ophthalmol Ther. 2023 Jan 24 [Online ahead of print]Subhi Y, Windfeld-Mathiasen J, … Horwitz H
  • CONCLUSIONS: Male androgen abusers were not at increased risk of CSC. Considering the lack of any signal in this large study, we speculate that if male androgen plays any direct role in the pathophysiology of CSC, its role may be subtle at best.
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