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7,726 results
  • Drugs and Lactation Database (LactMed) [BOOK]
  • BOOKNational Library of Medicine (US): Bethesda (MD)
  • No information is available on the use of succinylcholine during breastfeeding. Because it is rapidly eliminated and poorly absorbed orally, it is not likely to reach the bloodstream of the infant or...
  • GeneReviews® [BOOK]
  • BOOKUniversity of Washington, Seattle: Seattle (WA)
  • Adam MP, Ardinger HH, … Amemiya ABird TD
  • Myotonic dystrophy type 1 (DM1) is a multisystem disorder that affects skeletal and smooth muscle as well as the eye, heart, endocrine system, and central nervous system. The clinical findings, which...
  • [Performance of prehospital emergency anesthesia and airway management : An online survey]. [Journal Article]
  • AAnaesthesist 2018 Jun 29
  • Warnecke T, Dobbermann M, … Hinkelbein J
  • CONCLUSIONS: The results of the survey demonstrate heterogeneity in RSI techniques used by EMS physicians in Germany. Medical equipment and safe care practices, such as labeling of syringes varied considerably between different service areas. The recommendations of the S1 national guidelines on emergency airway management and anesthesia should be adhered to together with the implementation of local SOPs.
  • [Rapid sequence induction and intubation in patients with risk of aspiration : Recommendations for action for practical management of anesthesia]. [Journal Article]
  • AAnaesthesist 2018; 67(8):568-583
  • Eichelsbacher C, Ilper H, … Loop T
  • CONCLUSIONS: The consideration of all practical, clinical procedures in patients at risk for aspiration represents an effective prevention of pulmonary aspiration during the induction of anesthesia. These include the optimal drug pre-treatment with antacids (e. g. sodium citrate) for highly aspiration-endangered and proton pump inhibitors or H2 blockers in other patients the evening before. Each patient should be examined and explained prior to RSI according to the recommendations of the National German Society of Anesthesiology for preoperative evaluation. A RSI should be performed in patients with no 2h liquid and no 6h food fasting or acute vomiting, sub-ileus or ileus, or no protective reflexes or a gastrointestinal passenger disorder. In addition, RSI should be performed in pregnant women after the 3rd trimester and during birth. The expertise and competence of the physician before and during rapid sequence induction and intubation about the respective task distribution minimizes the risk of aspiration, as does the adequate equipment, as well as an optimized upper body elevation of the patient. Consistent pre-oxygenation with an FIO2 of 1.0 (FetO2-concentration > 0.9) and an oxygen flow > 10 l/min using a completely sealing respiratory mask with capnography should take 3-5 minutes. Fast enough deep anesthesia and muscle relaxation to avoid coughing and choking can be achieved by a combination of opioid, hypnotic and muscle relaxation. In addition, an opioid of choice, propofol, thiopental, etomidate and ketamine can be used as hypnotic and rocuronium with the availability of sugammadex should be used as muscle relaxant. If there are no contraindications, succinylcholine can also be used as a muscle relaxant. In case of an unexpected difficult airway, a 2nd generation extraglottic airway device should be used. During regurgitation or aspiration, intensive medical monitoring and fiber-optic bronchoscopy should be performed, depending on the degree of severity and an X‑ray thorax image or a CT scan should be performed if symptoms arise. Three factors reduce the risk of aspiration: expertise, support from an experienced anesthesiologist and close monitoring of an inexperienced anesthesiologist.
  • Rapid Sequence Intubation in Traumatic Brain-injured Adults. [Review]
  • CCureus 2018 Apr 25; 10(4):e2530
  • Kramer N, Lebowitz D, … Ganti L
  • Deciding on proper medication administration for the traumatic brain injury (TBI) patient undergoing intubation can be daunting and confusing. Pretreatment with lidocaine and/or vecuronium is no long...
  • [S1 guidelines on malignant hyperthermia : Update 2018]. [Review]
  • AAnaesthesist 2018; 67(7):529-532
  • Wappler F
  • The prevalence of malignant hyperthermia (MH) in Germany is 1:2000-1:3000 and therefore more common than previously assumed, so that anesthesia personnel will more often be confronted with susceptibl...
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