- Risk Factors for Complications following Introduction of Radical Surgery for Colon Cancer: A Consecutive Patient Series. [Journal Article]
- SJScand J Surg 2018 Sep 06; :1457496918798208
- CONCLUSIONS: Severe complications following the introduction of complete mesocolic excision are patient dependent and related to open surgery. Patients selected for laparoscopy had less number of complications; therefore, introducing complete mesocolic excision by laparoscopy is justified. Identification of these factors can improve selection of appropriate surgical approach and postoperative patient safety.
- Systematic review: Features, diagnosis, management and prognosis of hepatic hematoma, a rare complication of ERCP. [Review]
- DLDig Liver Dis 2018 Jul 20
- CONCLUSIONS: HH is a rare but severe complication following ERCP which needs a multidisciplinary approach. Antibiotics administration is the only treatment able to reduce the risk of death.
- Predicting patients requiring discharge to post-acute care facilities following primary total hip replacement: Does anesthesia type play a role? [Journal Article]
- JCJ Clin Anesth 2018 Jul 31; 51:32-36
- CONCLUSIONS: We developed a predictive model for post-acute care facility discharge following THR. The use of neuraxial anesthesia was associated with decreased odds for post-acute care facility discharge.
- An international consensus statement on the management of postoperative anaemia after major surgical procedures. [Review]
- AAnaesthesia 2018 Jul 31
- Despite numerous guidelines on the management of anaemia in surgical patients, there is no pragmatic guidance for the diagnosis and management of anaemia and iron deficiency in the postoperative peri...
Despite numerous guidelines on the management of anaemia in surgical patients, there is no pragmatic guidance for the diagnosis and management of anaemia and iron deficiency in the postoperative period. A number of experienced researchers and clinicians took part in a two-day expert workshop and developed the following consensus statement. After presentation of our own research data and local policies and procedures, appropriate relevant literature was reviewed and discussed. We developed a series of best-practice and evidence-based statements to advise on patient care with respect to anaemia and iron deficiency in the postoperative period. These statements include: a diagnostic approach to iron deficiency and anaemia in surgical patients; identification of patients appropriate for treatment; and advice on practical management and follow-up that is easy to implement. Available data allow the fulfilment of the requirements of Pillar 1 of Patient Blood Management. We urge national and international research funding bodies to take note of these recommendations, particularly in terms of funding large-scale prospective, randomised clinical trials that can most effectively address the important clinical questions and this clearly unmet medical need.
- Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study. [Journal Article]
- LHLancet Haematol 2018; 5(8):e333-e345
- CONCLUSIONS: Both ATP2B4 and the Dantu blood group antigen are associated with the structure and function of red blood cells. ATP2B4 codes for plasma membrane calcium-transporting ATPase 4 (the major calcium pump on red blood cells) and the glycophorins are ligands for parasites to invade red blood cells. Future work should aim at uncovering the mechanisms by which these polymorphisms can result in severe malaria protection and investigate the implications of these associations for wider health.
- Long-term nutritional follow-up post bariatric surgery. [Journal Article]
- COCurr Opin Clin Nutr Metab Care 2018; 21(5):388-393
- CONCLUSIONS: There is still a significant level of uncertainty regarding the best clinical practices for maintaining the health benefits provided by bariatric surgery. The role of family physician in postsurgery care needs to be clearly defined. More effort is needed to improve psychological care, behaviour management, and therapeutic patient education after bariatric surgery. A more patient-centred approach should probably be considered.
- Hereditary hemorrhagic telangiectasia: diagnosis and management from the hematologist's perspective. [Journal Article]
- HHaematologica 2018 May 24
- Hereditary Hemorrhagic Telangiectasia, also known as Osler-Weber-Rendu syndrome, is an autosomal dominant disorder that causes abnormal blood vessel formation. The diagnosis of hereditary hemorrhagic...
Hereditary Hemorrhagic Telangiectasia, also known as Osler-Weber-Rendu syndrome, is an autosomal dominant disorder that causes abnormal blood vessel formation. The diagnosis of hereditary hemorrhagic telangiectasia is clinical, based on the Curacao criteria. Genetic mutations that have been identified include ENG, ACVRL1/ALK1, and MADH4/SMAD4, among others. Patients with hereditary hemorrhagic telangiectasia may have telangiectasias and arteriovenous malformations in various organs and suffer from many complications including bleeding, anemia, iron deficiency, and high output heart failure. Families with the same mutation exhibit considerable phenotypic variation. Optimal treatment is best delivered via a multidisciplinary approach with appropriate diagnosis, screening and local and/or systemic management of lesions. Antiangiogenic agents such as bevacizumab have emerged as a promising systemic therapy in reducing bleeding complications but are not curative. Other pharmacologic agents include iron supplementation, antifibrinolytics and hormonal treatment. This review discusses the biology of hereditary hemorrhagic telangiectasia, management issues that face the practicing hematologist and considerations of future directions in hereditary hemorrhagic telangiectasia treatment.
- Patient blood management: how is implementation going?: A report comparing the 2015 survey with the 2013 survey of PBM in England. [Journal Article]
- TMTransfus Med 2018; 28(2):92-97
- Patient blood management (PBM) is an evidence-based approach to optimising the care of patients who might need transfusion. In 2013, all NHS Trusts in England were surveyed about their readiness to i...
Patient blood management (PBM) is an evidence-based approach to optimising the care of patients who might need transfusion. In 2013, all NHS Trusts in England were surveyed about their readiness to implement PBM. National PBM recommendations were launched in 2014.
- Successful Embolization of Bleeding Ileal Varices with N-butyl Cyanoacrylate via a Recanalized Paraumbilical Vein. [Journal Article]
- CICardiovasc Intervent Radiol 2018; 41(8):1291-1294
- A 48-year-old woman with alcoholic liver cirrhosis was admitted to our hospital because of hematochezia and severe anemia. She had been hospitalized many times over the past year for hematochezia of ...
A 48-year-old woman with alcoholic liver cirrhosis was admitted to our hospital because of hematochezia and severe anemia. She had been hospitalized many times over the past year for hematochezia of unknown etiology. Contrast-enhanced CT demonstrated ileal varices, which were fed by several ileal veins. These feeding veins were selectively embolized with N-butyl cyanoacrylate (NBCA) via a recanalized paraumbilical vein. The paraumbilical vein instead of the portal vein was punctured to decrease the risk of bleeding complications because she had coagulopathy and ascites. We consider antegrade embolization of ileal varices with NBCA to be a feasible and effective treatment. Access via a paraumbilical vein is an alternative to the transhepatic approach.Level of Evidence Level V, case report.
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- Caring for the Orthopaedic Patient With a History of Bariatric Surgery. [Case Reports]
- ONOrthop Nurs 2018 Mar/Apr; 37(2):106-112
- Bariatric surgery is performed on the gastrointestinal tract as a solution to obesity, and prevalence of these surgical procedures continues to rise. Bariatric surgery creates restrictive and/or mala...
Bariatric surgery is performed on the gastrointestinal tract as a solution to obesity, and prevalence of these surgical procedures continues to rise. Bariatric surgery creates restrictive and/or malabsorptive properties, causing nutritional deficits from the physiological changes in absorption and a hypoacidic environment. Although surgery induces sustained weight loss, decreases mortality, and provides resolution or improvement to comorbidities of obesity, it can also come with complications. Common long-term complications of bariatric surgery include malnutrition, anemia, impaired wound healing, and impaired bone health. It is essential that nurses and the healthcare team caring for orthopaedic individuals with a history of bariatric surgery be aware of the special needs of these individuals, especially in the promotion of bone health. Using a multidisciplinary approach for the advancement of the orthopaedic patient's health will help promote quality patient care.