- Clinical Characteristics, Treatment Patterns, and Effectiveness in Chinese Patients with Angina Pectoris Using Electronic Patient-Reported Outcomes: Protocol for a Multicenter, Prospective, Cohort Study (GREAT). [Journal Article]Adv Ther. 2023 Feb 04 [Online ahead of print]AT
- CONCLUSIONS: This study will evaluate the effectiveness of anti-anginal regimens using ePROs in real-world settings in China. The results from this study may provide a new perspective on treatment patterns and the effectiveness of different anti-anginal regimens for patients with AP.
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- A systematic review and meta-analysis of air pollution and angina pectoris attacks: identification of hazardous pollutant, short-term effect, and vulnerable population. [Review]Environ Sci Pollut Res Int. 2023 Feb 03 [Online ahead of print]ES
- We conducted a systematic review and meta-analysis of global epidemiological studies of air pollution and angina pectoris, aiming to explore the deleterious air pollutant(s) and vulnerable sub-populations. PubMed and Web of Science databases were searched for eligible articles published between database inception and October 2021. Meta-analysis weighted by inverse-variance was utilized to pool ef…
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- Clinical Outcome of Revascularization Deferral With Instantaneous Wave-Free Ratio and Fractional Flow Reserve: A 5-Year Follow-Up Substudy From the iFR-SWEDEHEART Trial. [Journal Article]J Am Heart Assoc. 2023 Feb 03 [Online ahead of print]JA
- Background Although physiology-based assessment of coronary artery stenosis using instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) are established methods of guiding coronary revascularization, its clinical outcome in long-term deferral needs further evaluation, especially with acute coronary syndrome as a clinical presentation. The aim was to evaluate the long-term clinical …
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- Long-term effect of a large dose of iodinated contrast in patients with mild thyroid dysfunction: a prospective cohort study. [Journal Article]Chin Med J (Engl). 2022 Dec 08 [Online ahead of print]CM
- CONCLUSIONS: Patients with T3 reduction are at risk of transient subclinical TD and hypothyroidism after a single large dose of ICM. Follow-up of this population at 9-12 months after ICM exposure is warranted.
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- The Coronary Sinus Reducer Stent for the Treatment of Refractory Angina Pectoris: From the Conception of Innovation to Clinical Application. [Journal Article]Cardiol Rev. 2022 Dec 28 [Online ahead of print]CR
- The Neovasc Coronary Sinus Reducer Stent (CSRS) was developed for the treatment of patients who continue to suffer from disabling symptoms despite optimal medical therapy. This patient population with refractory angina symptoms is expected to grow, since life expectancy of individuals with atherosclerotic coronary artery disease is increasing. In this paper, we discussed the development of a nove…
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- [Post-marketing effectiveness evaluation of traditional Chinese medicine in paradigm based on "proving efficacy, conforming standard, and exploring mechanism":a case study of Danhong Injection]. [Journal Article]Zhongguo Zhong Yao Za Zhi. 2023 Jan; 48(1):279-284.ZZ
- At present, new concepts, new technologies, and new methods are emerging in the field of medical research, breaking through the inherent thinking patterns and research models, and promoting the transformation of the research paradigm of traditional Chinese medicine(TCM). This paper gave a case study of clinical research in Danhong Injection in the treatment of chronic stable angina, and based on …
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- [Meta-analysis and GRADE evaluation of Guanxinning Tablets in treatment of angina pectoris of coronary heart disease]. [Meta-Analysis]Zhongguo Zhong Yao Za Zhi. 2023 Jan; 48(1):247-255.ZZ
- This study aims to evaluate the efficacy and safety of Guanxinning Tablets+conventional western medicine in the treatment of angina pectoris of coronary heart disease, and provide evidence-based references for clinical medication. Retrieved from CNKI, Wanfang, VIP, SinoMed, PubMed, EMbase, Cochrane Library, randomized controlled trial(RCT) about Guanxinning Tablets for the treatment of angina pec…
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- Evolving Management Paradigm for Stable Ischemic Heart Disease Patients: JACC Review Topic of the Week. [Review]J Am Coll Cardiol. 2023 Feb 07; 81(5):505-514.JACC
- Management of stable coronary artery disease (CAD) has been based on the assumption that flow-limiting atherosclerotic obstructions are the proximate cause of angina and myocardial ischemia in most patients and represent an important target for revascularization. However, the role of revascularization in reducing long-term cardiac events in these patients has been limited mainly to those with lef…
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- Resisting arrest: Perioperative confirmation and management of an iatrogenic aortocoronary arteriovenous fistula after coronary artery bypass grafting for redo cardiac surgery. [Case Reports]Ann Card Anaesth. 2023 Jan-Mar; 26(1):83-85.AC
- Although rare, iatrogenic aortocoronary arteriovenous fistulae (ACAVF) occur when a coronary graft is mistakenly anastomosed to an epicardial vein rather than its intended arterial target. Patients may be asymptomatic, demonstrate angina, dyspnea, arrhythmias, syncope, or diminished exercise capacity, and may have wide pulse pressures with evidence of coronary steal. A thorough insight into the d…
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- Rationale and design of the iCORONARY trial: improving the cost-effectiveness of coronary artery disease diagnosis. [Journal Article]Neth Heart J. 2023 Jan 31 [Online ahead of print]NH
- CONCLUSIONS: The iCORONARY trial will assess whether a strategy of FFR-CT or QFR is non-inferior to invasive angiography to guide the need for revascularisation in patients with stable CAD. Non-inferiority to the standard of care implies that these techniques are attractive, less-invasive alternatives to current diagnostic pathways.
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- Predictive value of high-sensitivity troponin for significant coronary artery disease in new-onset atrial fibrillation with rapid ventricular response. [Journal Article]Coron Artery Dis. 2023 Mar 01; 34(2):87-95.CA
- CONCLUSIONS: HS-cTnT exhibits potential as an effective screening biomarker to predict nonsignificant CAD in new rapid AF, allowing more targeted and rationalized ischemic testing. HS-cTnT may also be a more accurate predictor of significant CAD than clinically suspected stable angina.Graphical abstract: http://links.lww.com/MCA/A540.
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- Coronary artery disease in a patient with Addison's disease: a case report and literature review. [Case Reports]
- CONCLUSIONS: The combination of Addison's disease and coronary artery disease in one patient is rare. Addison's disease can induce inflammation and disorders of water and electrolyte metabolism, which may further accelerate the course of coronary artery disease. Meanwhile, the hypotension in Addison's disease may affect the coronary blood flow, which may result in an increased susceptibility to unstable angina in the presence of coronary stenosis. So, we should analyze comprehensively if the coronary artery disease progress rapidly.
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- The association between denture use and cardiovascular diseases. The United States National Health and Nutrition Examination Survey 2009-2018. [Journal Article]
- CONCLUSIONS: In this nationally representative survey, denture use was associated with CVD. Denture use may be an unconventional risk factor for assessing CVD risks, especially in women. Future studies are required to investigate whether CVD and denture use is causally related.
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- HEMOSTASIS DISORDERS IN CORONARY ARTERY DISEASE: A PROSPECTIVE COMPARATIVE STUDY OF 130 PATIENTS. [Journal Article]Georgian Med News. 2022 NovGM
- The laboratory detection of factors that participate in coagulation mechanisms in patients with coronary heart disease may lead to important findings regarding the contribution of endothelial function to atherosclerotic lesions of coronary arteries. The main purpose of this study was to investigate the role of high-sensitivity C-reactive protein (hs-CRP), von Willebrand factor (vWF) activity, thr…
- The correlation between speckle-tracking echocardiography and coronary angiography in suspected coronary artery disease with normal left ventricular function. [Journal Article]J Cardiovasc Thorac Res. 2022; 14(4):234-239.JC
- Introduction: Our study objects to determine the diagnostic accuracy of two-dimensional speckle tracking echocardiography (2DSTE) in predicting presence and severity of coronary artery disease (CAD). Methods: Patients with stable angina pectoris with normal left ventricular function (>50%) undergoing coronary angiography were enrolled and subjected to speckle tracking echocardiography. Global lon…
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- Effectiveness and safety of selected traditional Chinese medicine injections in patients with combined diabetes mellitus and coronary heart disease: A systematic review and network meta-analysis of randomized clinical trials. [Systematic Review]Front Pharmacol. 2022; 13:1060956.FP
- Background: In view of the high morbidity and mortality of Diabetes mellitus-Coronary heart disease (DM-CHD) in diabetics, the combination therapy of traditional Chinese medicine injections (TCMIs) and conventional therapy (CT) is receiving extensive attention. Therefore, the effectiveness and security of conventional therapy with traditional Chinese medicine injections in the therapy of diabetes…
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- Prognostic Implication of Small Dense LDL-Cholesterol Levels following Acute Coronary Syndrome. [Journal Article]
- Background and Objectives: Small dense LDL cholesterol is a strong risk factor for atherosclerosis. However, few studies have investigated the impacts of this specific lipid profile on the incident risk of adverse cardiovascular events in patients with acute coronary syndrome. Materials and Methods: Patients with acute coronary syndrome, who underwent revascularization, were included and followed…
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- Normonatremic Transient Renal Salt Wasting (TRSW) Is Not Rare in a Department of Internal Medicine. [Journal Article]
- CONCLUSIONS: Normonatremic TRSW is not a rare observation, particularly in patients with neurological or cardiac problems.
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- Circulating Regulatory B-Lymphocytes in Patients with Acute Myocardial Infarction: A Pilot Study. [Journal Article]
- CONCLUSIONS: Circulating B-regs are reduced in patients with MI compared to patients with SAP. This finding may shed further light on the inflammatory pathophysiologic factors related to plaque rupture.
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- A Systematic Review of CD34+ Stem Cell Therapy as an Innovative and Efficient Treatment for the Management of Refractory Angina. [Review]
- Despite optimal medical treatment, many individuals suffering from severe coronary artery disease are not suitable candidates for further revascularization. Therapeutic angiogenesis has attracted continuous interest to increase myocardial perfusion. Cell therapy using autologous stem cells expressing Cluster of Differentiation 34 plus (CD34+) offers a special therapeutic choice for individuals wi…
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- The association of BP with cardiovascular outcomes in patients with dipstick proteinuria and preserved kidney function. [Journal Article]
- Little is known about the relationship between blood pressure (BP) and incident cardiovascular disease (CVD) in people with proteinuria and a preserved estimated glomerular filtration rate (eGFR). This study sought to investigate the association of BP with CVD risk in adults with proteinuria and preserved eGFR. We studied 188,837 individuals with proteinuria and preserved eGFR ≥60 mL/min/1.73 m2.…
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- Declined plasma microfibrillar-associated protein 4 levels in acute coronary syndrome. [Journal Article]
- CONCLUSIONS: MFAP4 has a potential as a biomarker for the degree of coronary stenosis in ACS. Confirmation of observations in larger cohorts and longer follow-up periods is warranted.
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- Quantitative flow ratio versus fractional flow reserve for guiding percutaneous coronary intervention: design and rationale of the randomised FAVOR III Europe Japan trial. [Journal Article]EuroIntervention. 2023 Jan 17 [Online ahead of print]E
- Quantitative flow ratio (QFR) is a computation of fractional flow reserve (FFR) based on invasive coronary angiographic images. Calculating QFR is less invasive than measuring FFR and may be associated with lower costs. Current evidence supports the call for an adequately powered randomised comparison of QFR and FFR for the evaluation of intermediate coronary stenosis. The aim of the FAVOR III Eu…
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- The effect of dance on rehabilitation training after COVID-19. [Journal Article]Eur Rev Med Pharmacol Sci. 2023 Jan; 27(1):359-365.ER
- CONCLUSIONS: The intensity and frequency of aerobic dance play a key role in the effect of cognitive improvement, requiring long-term persistence and ensuring the intensity and frequency of training. Second, the patient's processing speed (P300 latency) tends to gradually extend with the passage of time, and aerobic dance intervention helps shortening the P300 latency, suggesting that patients can delay the decline of their cognitive function through early aerobic dance intervention.
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- Treatment strategy for spontaneous coronary artery dissection based on anatomical characteristics. [Journal Article]
- CONCLUSIONS: Conservative management remains the recommended treatment strategy for the low-risk SCAD patients. PCI could be considered in high-risk SCAD patients with favorable clinical outcomes and vessel healing. Characterization of lesion anatomy may be an important indicator for treatment decision.
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- Long term clinical outcome after success re-attempt percutaneous coronary intervention of chronic total occlusion. [Journal Article]
- CONCLUSIONS: For the patients with previous CTO-PCI failure, a successful re-attempt CTO-PCI was associated with significantly lower MACE, which was primarily driven by a lower TVR rate. More complex CTO lesions and longer stents were the independent predictors of TVR after successful CTO-PCI.
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- Comparison of various calcium antagonist on vasospastic angina: a systematic review. [Journal Article]
- CONCLUSIONS: Diltiazem, nifedipine and amlodipine are potent in decreasing VSA, however, tailoring specific CCBs adverse reactions to patient condition and the drug preparation would be substantially beneficial for the outcome.
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- [Eructonesius: a little known symptom of myocardial ischaemia]. [Case Reports]Ned Tijdschr Geneeskd. 2022 Nov 02; 166NT
- CONCLUSIONS: Myocardial ischaemia does not necessarily present with typical angina. More often patients present with vague, atypical complaints. Therefore, a low-threshold to consider myocardial ischaemia in the differential diagnosis of such complaints remains important, especially if other diagnostic clues are present.
- Neuromodulation in patients with refractory angina pectoris: a review. [Review]
- The number of patients with coronary artery disease (CAD) who have persisting angina pectoris despite optimal medical treatment known as refractory angina pectoris (RAP) is growing. Current estimates indicate that 5-10% of patients with stable CAD have RAP. In absolute numbers, there are 50 000-100 000 new cases of RAP each year in the USA and 30 000-50 000 new cases each year in Europe. The term…
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- l-carnitine: Nutrition, pathology, and health benefits. [Review]
- Carnitine is a medically needful nutrient that contributes in the production of energy and the metabolism of fatty acids. Bioavailability is higher in vegetarians than in people who eat meat. Deficits in carnitine transporters occur as a result of genetic mutations or in combination with other illnesses such like hepatic or renal disease. Carnitine deficit can arise in diseases such endocrine mal…
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