- Associations of 26 Circulating Inflammatory and Renal Biomarkers with Near-Infrared Spectroscopy and Long-term Cardiovascular Outcome in Patients Undergoing Coronary Angiography (ATHEROREMO-NIRS Substudy). [Review]
- CACurr Atheroscler Rep 2018 Sep 14; 20(10):52
- The purpose of this study was to investigate the association of 26 inflammatory biomarkers (acute phase proteins, cytokines, chemokines) and renal markers with coronary lipid core burden index (LCBI)...
The purpose of this study was to investigate the association of 26 inflammatory biomarkers (acute phase proteins, cytokines, chemokines) and renal markers with coronary lipid core burden index (LCBI) assessed by near-infrared spectroscopy (NIRS) imaging, as well as the association of these biomarkers with long-term cardiovascular outcome.
- A journey through chaos and calmness: experiences of mindfulness training in patients with depressive symptoms after a recent coronary event - a qualitative diary content analysis. [Journal Article]
- BPBMC Psychol 2018 Sep 13; 6(1):46
- CONCLUSIONS: Introducing MBSR in the aftermath of a cardiac event, when depressive symptoms are present, is a complex and delicate challenge in clinical practice. More nuanced information about what to expect as well as the addition of motivational support and skillful guidance during the course should be given in accordance with the participants' experiences and needs.
- Alterations in heart rate variability in patients with peripheral arterial disease requiring surgical revascularization have limited association with postoperative major adverse cardiovascular and cerebrovascular events. [Journal Article]
- PlosPLoS One 2018; 13(9):e0203519
- CONCLUSIONS: HRV is altered in patients with PAD. These alterations have a limited association with OSA and MACCE.
- Effects of trans-endocardial delivery of bone marrow-derived CD133+ cells on angina and quality of life in patients with refractory angina: A sub-analysis of the REGENT-VSEL trial. [Journal Article]
- CJCardiol J 2018; 25(4):521-529
- CONCLUSIONS: Intra-myocardial delivery of autologous CD133+ stem cells is safe and feasible but does not show a significant improvement in the QoL or angina pectoris symptoms in patients with chronic myocardial ischemia.
- NICORANDIL EFFICACY IN THE TREATMENT OF ISCHEMIC HEART DISEASE (REVIEW). [Journal Article]
- GMGeorgian Med News 2018 Jul-Aug; (280-281):152-155
- Nicorandil is an antianginal agent with a dual mechanism of action. It belongs to ATP-senitive potassium channel openers which has the beneficial effect in angina pectoris, playing an significant rol...
Nicorandil is an antianginal agent with a dual mechanism of action. It belongs to ATP-senitive potassium channel openers which has the beneficial effect in angina pectoris, playing an significant role in the dilation of arteries, veins and coronary artery. It leads to the relaxation of vascular smooth muscle and causes vasodilatation of major epicardial vessels. This effect is crucial for reducing risks of further damage in cases when percutaneous coronary intervention (PCI) is necessary. Relevant new studies concluded that Nicorandil has antiarrhythmic and cardioprotective effects by improving reperfusion, ultimately leading to a reduction in microvascular damage caused by PCI. Furthermore, Nicorandil addition to the standard therapy of paitents with ischemic heart disease has demonstrated improved quality of life.
- Effect of doxycycline and atorvastatin on improving exercise tolerance in patients with angina pectoris. [Journal Article]
- PJPak J Pharm Sci 2018; 31(4(Special)):1731-1735
- The therapeutic effect of statins on the stabilization of atherosclerotic plaques has been affirmed. In recent years, the inhibition of matrix metalloproteinases (MMPS) of tetracycline drug doxycycli...
The therapeutic effect of statins on the stabilization of atherosclerotic plaques has been affirmed. In recent years, the inhibition of matrix metalloproteinases (MMPS) of tetracycline drug doxycycline has attracted more and more attention. In this paper, we observed the effect of atorvastatin and doxycycline on exercise tolerance in patients with stable angina pectoris. The results showed that there was no significant difference in the clinical efficacy of the two groups and the effect on the exercise tolerance (P<0.05). There were 4 cases of mild gastrointestinal reaction in the doxycycline group and no other serious adverse reactions. The total effective rate of treatment in the doxycycline group was 93.3%. Doxycycline treatment significantly reduced the frequency of angina pectoris and the incidence of cardiovascular events, and the treatment effect was better. To sum up, we think doxycycline is a safe, cheap, therapeutic drug to stabilize plaque.
- Intramural Coronary Amyloidosis Mimicking Effort Angina Pectoris Preceding Fatal Heart Failure. [Journal Article]
- CJCirc J 2018 Sep 08
- Vasospastic angina: A literature review of current evidence. [Review]
- ACArch Cardiovasc Dis 2018 Sep 06
- Vasospastic angina (VSA) is a variant form of angina pectoris, in which angina occurs at rest, with transient electrocardiogram modifications and preserved exercise capacity. VSA can be involved in m...
Vasospastic angina (VSA) is a variant form of angina pectoris, in which angina occurs at rest, with transient electrocardiogram modifications and preserved exercise capacity. VSA can be involved in many clinical scenarios, such as stable angina, sudden cardiac death, acute coronary syndrome, arrhythmia or syncope. Coronary vasospasm is a heterogeneous phenomenon that can occur in patients with or without coronary atherosclerosis, can be focal or diffuse, and can affect epicardial or microvasculature coronary arteries. This disease remains underdiagnosed, and provocative tests are rarely performed. VSA diagnosis involves three considerations: classical clinical manifestations of VSA; documentation of myocardial ischaemia during spontaneous episodes; and demonstration of coronary artery spasm. The gold standard diagnostic approach uses invasive coronary angiography to directly image coronary spasm using acetylcholine, ergonovine or methylergonovine as the provocative stimulus. Lifestyle changes, avoidance of vasospastic agents and pharmacotherapy, such as calcium channel blockers, nitrates, statins, aspirin, alpha1-adrenergic receptor antagonists, rho-kinase inhibitors or nicorandil, could be proposed to patients with VSA. This review discusses the pathophysiology, clinical spectrum and management of VSA for clinicians, as well as diagnostic criteria and the provocative tests available for use by interventional cardiologists.
- [Angina pectoris in a 47-year-old athletic man with psoriasis vulgaris]. [Journal Article]
- IInternist (Berl) 2018 Sep 07
- A 47-year-old man presented with angina pectoris complaints in the chest pain unit. Due to psoriasis and psoriatic arthritis he had been systemically treated for 4 years. Because of an increased card...
A 47-year-old man presented with angina pectoris complaints in the chest pain unit. Due to psoriasis and psoriatic arthritis he had been systemically treated for 4 years. Because of an increased cardiovascular risk profile, coronary heart disease (CHD) was suspected and an invasive coronary diagnosis was performed. In the cardiac catheterization, CHD could be detected and treated in the same session. The risk of CHD in patients with psoriasis is increased due to a higher incidence of risk factors but also the disease itself. Patients with psoriasis should regularly undergo cardiovascular risk screening.
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- Cardiac rehabilitation therapy for coronary slow flow phenomenon. [Journal Article]
- HERZHerz 2018 Sep 06
- CONCLUSIONS: Cardiac rehabilitation can reduce the plasma levels of LDL-C, TG, hs-CRP, Hcy and Arg, significantly improve the symptoms of coronary slow flow phenomenon and accelerate the speed of coronary artery blood flow.