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1,591 results
  • Comparison of two pediatric cases requiring the use of bivalirudin during cardiopulmonary bypass. [Journal Article]
  • PPerfusion 2018 Apr 01; :267659118767374
  • Bryant ME, Regan WL, … Matte GS
  • CONCLUSIONS: The literature strongly supports a specific infusion rate1-7 (2.5 mg/kg/h) for bivalirudin anticoagulation during extracorporeal circulation. Clinicians must consider the loss of clotting factors and the administration of blood products while adjusting the bivalirudin infusion during bypass. We have now elected to maintain an infusion rate of ≥0.5 mg/kg/h for bivalirudin anticoagulation at our center, based on institutional experience, though consideration for a higher infusion rate for an added margin of safety should be considered. It is imperative to have a well-developed protocol for the management of these cardiopulmonary bypass patients and we offer our one-page timeline of events to help guide other pediatric centers looking to use bivalirudin anticoagulation.
  • Early stent thrombosis: Nearly gone, but never forgotten. [Editorial]
  • CCCatheter Cardiovasc Interv 2018 Apr 01; 91(5):849-850
  • Seto AH, Kern MJ
  • Early stent thrombosis occurs in ∼1% of patients treated with primary PCI and increases shock, stroke, and mortality. Early stent thrombosis was associated with small stent diameter, failure to use g...
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