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(Angiostrongyliasis cantonensis)
719 results
  • Autochthonous Angiostrongylus cantonensis Lungworms in Urban Rats, Valencia, Spain, 2021. [Journal Article]
    Emerg Infect Dis. 2022 12; 28(12):2564-2567.Galán-Puchades MT, Gómez-Samblás M, … Fuentes MV
  • To determine the role of rats as potential reservoirs of zoonotic parasites, we examined rats trapped in urban sewers of Valencia, Spain, in 2021. Morphologic and molecular identification and sequencing identified autochthonous Angiostrongylus cantonensis nematodes, the most common cause of human eosinophilic meningitis, in pulmonary arteries of Rattus norvegicus and R. rattus rats.
  • Neuroangiostrongyliasis: Global Spread of an Emerging Tropical Disease. [Journal Article]
    Am J Trop Med Hyg. 2022 12 14; 107(6):1166-1172.Cowie RH, Ansdell V, … Rollins RL
  • Neuroangiostrongyliasis (NAS) is an emerging parasitic disease caused by the neurotropic nematode Angiostrongylus cantonensis. Since it was first discovered, in rats in southern China in the 1930s, this tropical to subtropical parasite has spread to much of Southeast Asia, the Pacific Islands (including Hawaii), Australia, Japan, South America, the southeastern United States, the Caribbean, Afric…
  • Epidemiological, clinical and laboratory aspects of Angiostrongylus cantonensis infection: an integrative review. [Review]
    Braz J Biol. 2022; 82:e262109.Carvalho MSN, Carvalho MR, … Matos-Rocha TJ
  • This integrative literature review study analyzes the findings of the last 5 years of the parasite Angiostrongylus cantonensis. It is known that this nematode is found in the pulmonary arteries of rats, where it remains as a definitive host. From mice, the cycle spreads to animals, such as snails, which in contact with humans can trigger the disease. In humans, the parasite causes several neurolo…
  • A Rare Etiology for Ascending Paralysis in an Infant. [Journal Article]
    J Pediatric Infect Dis Soc. 2022 Oct 25; 11(10):448-451.Abe K, Casamina C, … Purohit PJ
  • An 11-month-old male infant with ascending paralysis had an unremarkable initial cerebrospinal fluid (CSF) analysis and imaging. Progressive neurological symptoms resulted in repeated CSF sampling, microscopy, and plasma microbial cell-free DNA next-generation sequencing analysis, that in combination with epidemiology, confirmed the diagnosis.
  • Susceptibility of Angiostrongylus cantonensis Larvae to Anthelmintic Drugs. [Journal Article]
    Front Pharmacol. 2022; 13:901459.Roquini DB, Silva GL, … De Moraes J
  • Human helminthiasis affects approximately one in five people in the world and disproportionally affects the poorest and most deprived communities. Human angiostrongyliasis, caused by nematode Angiostrongylus cantonensis, is a neglected emerging disease with escalating importance worldwide. Chemotherapy is the main control method for helminthiasis, but the therapeutic arsenal is limited. This stud…
  • Stat3/IL-6 signaling mediates sustained pneumonia induced by Agiostrongylus cantonensis. [Journal Article]
    PLoS Negl Trop Dis. 2022 05; 16(5):e0010461.Zhou H, Lu Y, … Lv Z
  • Angiostrongylus cantonensis (AC) is well-documented that parasitizes the host brain and causes eosinophilic meningitis. The migration route of AC in permissive hosts is well demonstrated, while in nonpermissive hosts, it remains to be fully defined. In the present study, we exploited live imaging technology, morphological and pathological configuration analysis, and molecular biological technolog…
  • Angiostrongylus cantonensis Nematode Invasion Pathway, Mallorca, Spain. [Journal Article]
    Emerg Infect Dis. 2022 06; 28(6):1163-1169.Delgado-Serra S, Sola J, … Paredes-Esquivel C
  • Neural angiostrongyliasis is an emerging zoonosis caused by the rat lungworm, Angiostrongylus cantonensis. In humans, infection with this nematode often results in eosinophilic meningitis and other severe disorders of the central nervous system. Europe was deemed a nonendemic region until 2018, when A. cantonensis worms were detected on the Mediterranean island of Mallorca, Spain, a tourism hotsp…
  • Angiostrongylus cantonensis in a Red Ruffed Lemur at a Zoo, Louisiana, USA. [Journal Article]
    Emerg Infect Dis. 2022 05; 28(5):1058-1060.Rizor J, Yanez RA, … Kiupel M
  • A red ruffed lemur (Varecia rubra) from a zoo in Louisiana, USA, was euthanized for worsening paresis. Brain and spinal cord histology identified eosinophilic meningoencephalomyelitis with intralesional adult Angiostrongylus sp. nematodes. PCR and sequencing confirmed A. cantonensis infection, indicating this parasite constitutes an emerging zoonosis in the southeastern United States.
  • Eosinophilic meningitis due to A. Cantonensis revealed at autopsy. [Case Reports]
    Indian J Pathol Microbiol. 2022 Apr-Jun; 65(2):420-421.Chaudhari JP, Shenoy AS, Goel NA
  • Parasitic infection of the central nervous system could be fatal, and its incidence is rising due to increasing worldwide travel. Amongst the various nematodes, Angiostrongylus contonensis is the commonest and causes eosinophilic meningitis. It is a zoonotic disease produced due to the ingestion of raw or undercooked snails or slugs. Most cases of angiostrongyliasis are mild and self-limiting, bu…
  • Angiostrongylosis meningomyelitis without blood eosinophilia. [Case Reports]
    J Infect Dev Ctries. 2021 12 31; 15(12):1933-1936.Amornpojnimman T, Sanghan N, … Sathirapanya P
  • Angiostrongylus cantonensis and Gnathostoma spinigerum usually cause eosinophilic meningitis with associated peripheral blood eosinophilia. A 44-year-old man developed acute paraplegia with bowel and bladder dysfunction. Spinal magnetic resonance images showed a long T2W hyperintensity signal from the 1st to 8th spinal thoracic level. Cerebrospinal fluid analysis revealed eosinophilia and elevate…
  • Heme oxygenase-1 modulates brain inflammation and apoptosis in mice with angiostrongyliasis. [Journal Article]
    Parasitol Int. 2022 Apr; 87:102528.Chen KM, Lan KP, Lai SC
  • The rat nematode lungworm Angiostrongylus cantonensis undergoes obligatory intracerebral migration in its hosts and causes eosinophilic meningitis or meningoencephalitis. Heme oxygenase 1 (HO-1) has several cytoprotective properties such as anti-oxidative, anti-inflammatory, and anti-apoptotic effects. HO-1 in brain tissues was induced in A. cantonensis-infected group and showed positive modulati…
  • Angiostrongylosis in Animals and Humans in Europe. [Review]
    Pathogens. 2021 Sep 25; 10(10)Morgan ER, Modry D, … Traversa D
  • Lungworms in the genus Angiostrongylus cause disease in animals and humans. The spread of Angiostrongylus vasorum within Europe and the recent establishment of Angiostrongylus cantonensis increase the relevance of these species to veterinary and medical practitioners, and to researchers in parasitology, epidemiology, veterinary science and ecology. This review introduces the key members of the ge…
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