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Unbound Medicine.
(Anorectal infections)
1,982 results
  • [Implantation metastasis of colorectal adenocarcinoma in an anal fistula]. [Case Reports]
    Orv Hetil. 2023 Jan 22; 164(3):110-113.Barcsák G, Szilágyi A, … Altorjay Á
  • In our case report, we describe a rare form of metastatic colorectal carcinoma, in which tumor cells spread intraluminally and metastasis occurs with implantation mechanism far from the primary tumor. A 43-year-old male patient developed perianal abscess. After surgical intervention a fistula-in-ano appeared at the site of the abscess. Fistulotomy was performed in another hospital. A few months l…
  • Crohn's Disease-Associated and Cryptoglandular Fistulas: Differences and Similarities. [Review]
    J Clin Med. 2023 Jan 06; 12(2)Zhou Z, Ouboter LF, … van der Meulen-de Jong AE
  • Perianal fistulas are defined as pathological connections between the anorectal canal and the perianal skin. Most perianal fistulas are cryptoglandular fistulas, which are thought to originate from infected anal glands. The remainder of the fistulas mainly arises as complications of Crohn's disease (CD), trauma, or as a result of malignancies. Fistulas in CD are considered as a consequence of a c…
  • Comprehensive Review of Anal Cytology. [Review]
    Acta Cytol. 2023 Jan 10 [Online ahead of print]Hopp AM, Puzyrenko A, Giorgadze T
  • CONCLUSIONS: Anal cytology is one modality that is a mainstay of many suggested screening guidelines. Interpretation and reporting follow current criteria for cervical/vaginal cytology per the Bethesda System, with site-specific alterations and changes in adequacy criteria to better accommodate some of the confounding factors encountered in anal cytology. While there are some limitations, such as a tendency to underestimate the degree of dysplasia and variable interobserver concordance rates, anal cytology, especially liquid-based preparations, overall performs well in detecting anal abnormalities and acts as an adequate screening tool. Importantly, most anal squamous dysplasias and cancers are also associated with human papillomavirus (HPV) infection, raising the possibility of HPV testing or genotyping as a component of screening and/or follow-up. Studies have also shown the efficacy of HPV vaccination in preventing anal lesions. Digital anorectal exam as well as anoscopy, particularly high-resolution anoscopy, are also often components of screening and follow-up. Management guidelines such as those put forth by the American Society for Colposcopy and Cervical Pathology (ASCCP) for cervical cancer are also not established for anal cancer. However, studies such as the Anal Cancer HSIL Outcomes Research (ANCHOR) trial have made significant strides in demonstrating successes in follow-up and treatment of anal lesions, findings that are crucial for establishing prevention and management guidelines going forward.
  • Addressing the risk of monkeypox exposure during gastrointestinal endoscopy. [Review]
    Ann Gastroenterol. 2023 Jan-Feb; 36(1):1-5.Canakis A, Kim RE, … Raufman JP
  • The current monkeypox virus (MPV) outbreak is now a global health concern. MPV, a zoonotic double-stranded DNA virus, may be transmitted from human to human or by contaminated surfaces. Understanding the clinical characteristics and risks of MPV transmission are important, especially for health care workers, who may unknowingly encounter the virus while fulfilling their clinical responsibilities.…
  • Myocarditis in monkeypox-infected patients: a case series. [Journal Article]
    Clin Microbiol Infect. 2022 Dec 09 [Online ahead of print]Dumont M, Guilhou T, … de La Porte des Vaux C
  • CONCLUSIONS: These cases suggest an association between monkeypox infections and cardiac inflammatory complications. The development of chest pain in an infected patient should not be underestimated and should lead to prompt investigations for myocarditis. Monkeypox infection should also be included in the differential diagnosis of myocarditis, particularly in at-risk patients such as men who have sex with men with multiple partners in whom complete examination for skin or mucosal lesions should thus be performed.
  • Monkeypox. [Review]
    Lancet. 2023 01 07; 401(10370):60-74.Mitjà O, Ogoina D, … Orkin CM
  • Monkeypox is a zoonotic illness caused by the monkeypox virus, an Orthopoxvirus in the same genus as the variola, vaccinia, and cowpox viruses. Since the detection of the first human case in the Democratic Republic of the Congo in 1970, the disease has caused sporadic infections and outbreaks, mainly restricted to some countries in west and central Africa. In July, 2022, WHO declared monkeypox a …
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