- [A Case of Robot-Assisted Abdominoperineal Resection with Prostatectomy for Locally Advanced Rectal Cancer]. [Journal Article]Gan To Kagaku Ryoho. 2022 Dec; 49(13):1690-1692.GT
- The patient was referred to our hospital because of bloody stool and anorectal pain, and a colonoscopy revealed a tumor in the lower rectum. Although no distant metastasis was found, the tumor was suspected to have invaded the distal prostate. Neoadjuvant chemoradiotherapy(45 Gy/25 Fr with S-1)resulted in tumor shrinkage and symptomatic improvement, however, the primary tumor remained in close pr…
- Effectiveness of a high fiber diet in improving constipation in patients with defecatory dyssynergy under treatment with anorrectal biofeedback. Exploratory, randomized clinical trial. [Journal Article]Gastroenterol Hepatol. 2023 Jan 30 [Online ahead of print]GH
- CONCLUSIONS: In patients with defecatory dyssynergy, a high-fiber diet not only does not improve the efficacy of anorectal biofeedback but is associated with a loss of improvement in abdominal symptoms. Research Registry. Nº: 8468.
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- Prevalence and Correlates of Depression and Anxiety in Patients with Functional Anorectal Pain. [Journal Article]
- CONCLUSIONS: Depressive and anxiety symptoms are prevalent in patients with FAP. Several socio-demographic and clinical predictors have been identified. There is a need for psychologists to be involved in the treatment of patients with FAP. Thus, multidisciplinary treatment may be the optimal treatment strategy.
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- Effect of single spinal anesthesia with two doses ropivacaine on urinary retention after hemorrhoidectomy in male patients. [Journal Article]
- CONCLUSIONS: Single spinal anesthesia with 10 mg 0.5% ropivacaine not only provides satisfactory anesthetic effect for hemorrhoidectomy but also has less influence on postoperative uroschesis and is worthy of clinical application.
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- Gracilis muscle transposition in complex anorectal fistulas of diverse types and etiologies: long-term results of 60 cases. [Journal Article]
- CONCLUSIONS: Based on the authors' experience, GMT is an effective therapeutic option for the treatment of complex fistulas when other therapeutic attempts have failed and should therefore be considered earlier in the treatment process. It should be seen as the main but not the only step, as additional procedures may be required for complete closure in some cases.
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- House advancement flap anoplasty in anal stenosis post hemorrhoids surgery. A case report. [Case Reports]
- CONCLUSIONS: Anal stenosis is a rare condition which requires good evaluation for its better management. Given its simplicity and successful results, a House Advancement Flap anoplasty is a reliable treatment of severe anal stenosis.
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- Single-stapling technique versus hand-sewn anastomosis in inter-sphincteric resection with transanal total mesorectal excision (Super SST): protocol for a multicentre randomized clinical trial. [Journal Article]
- CONCLUSIONS: This trial will provide important clinical insights for new and promising anastomotic options for patients with very low rectal cancer. Registration number: UMIN000047818 (https://www.umin.ac.jp/ctr/index-j.htme).
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- Comparing the efficacy and safety of different analgesic strategies after open hemorrhoidectomy: a systematic review and network meta-analysis. [Review]Int J Colorectal Dis. 2023 Jan 07; 38(1):4.IJ
- CONCLUSIONS: Diltiazem ointment may be the most effective medication for pain relief following open hemorrhoidectomy, and it can dramatically reduce pain within one week of surgery. The second and third recommended medications are BT and sucralfate ointment. GTN has a significant advantage in alleviating pain 24 h after open hemorrhoidectomy, but whether it causes headache is debatable; thus, it should be used with caution. EA's analgesic efficacy is still unknown. There was limited evidence on the safety of the intervention in this study, and it was simply presented statistically.
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- Pelvic floor physical therapy in patients with chronic anal fissure: long-term follow-up of a randomized controlled trial. [Randomized Controlled Trial]
- CONCLUSIONS: In the PAF-trial, we demonstrated that pelvic floor physical therapy yields a significant and clinical benefit in the time course and therefore should be advocated as adjuvant conservative treatment in patients with chronic anal fissure.
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- Experiencing multiple concurrent functional gastrointestinal disorders is associated with greater symptom severity and worse quality of life in chronic constipation and defecation disorders. [Journal Article]Neurogastroenterol Motil. 2022 Dec 28 [Online ahead of print]NM
- CONCLUSIONS: Functional gastrointestinal disorders comorbidity is highly prevalent in chronic constipation and defecatory disorders, and this is associated with greater symptom severity and worse QoL. Multimodal treatments targeting comorbid FGIDs may lead to superior outcomes.
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- Adenocarcinoma arising in an ectopic enterogenous cyst: A rare case report and review of literature. [Case Reports]
- Enterogenous cyst (EC) is a rare congenital lesion generally located in the central nervous system, such as in the cerebral hemispheres, posterior fossa, or spinal canal. They are usually benign lesions, and malignant transformation is rare. A 42-year-old woman felt an obvious pain in the lump and went to a local hospital for local lumpectomy. After 7 months, she again felt pain in the buttocks a…
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- Understanding the Female Physical Examination in Patients with Chronic Pelvic and Perineal Pain. [Journal Article]
- (1) Background: The objective was to compare the exploration of chronic pelvic pain syndrome (CPPS) patients in different locations and establish the role of physical examination in CPPS patients. (2) Methods: We reviewed clinical data from 107 female patients with CPPS unresponsive to conventional therapies at Puerta de Hierro University Hospital Madrid, Spain, from May 2018 to June 2022. Patien…
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- Electroacupuncture for postoperative pain in mixed hemorrhoids: A meta-analysis. [Meta-Analysis]
- CONCLUSIONS: Electroacupuncture can improve pain after surgery for mixed hemorrhoids. It is an effective method to improve the pain after hemorrhoidectomy, which deserves further research and promotion.
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- The negative impact of opioids on cancer patients treated with immune checkpoint inhibitors: a systematic review and meta-analysis. [Review]J Cancer Res Clin Oncol. 2022 Dec 20 [Online ahead of print]JC
- CONCLUSIONS: Opioids significantly reduced OS and PFS in patients receiving ICI therapy. Thus, the use of different types of opioids should be considered with caution, and it is necessary to actively develop alternative treatments.
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- Unilateral sacral erector spinae plane block for lower limb surgery in children. [Case Reports]
- The erector spinae plane block is a versatile regional anaesthesia technique used for a variety of truncal surgeries. A novel variation is the sacral erector spinae plane block which is gaining popularity for perineal and anorectal procedures. Local anaesthetic injected at this level blocks the sacral dermatomes and has the potential for more proximal spread to involve lumbar nerve fibres via spr…
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- Pelvic floor physical therapy in the treatment of chronic anal fissure (PAF trial): quality of life outcome. [Randomized Controlled Trial]
- CONCLUSIONS: The results of this study provide evidence that treatment by pelvic floor physical therapy improves quality of life and reduces pain, making it an important tool in management of chronic anal fissure and concomitant pelvic floor dysfunction.
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- Myocarditis in monkeypox-infected patients: a case series. [Journal Article]
- CONCLUSIONS: These cases suggest an association between monkeypox infections and cardiac inflammatory complications. The development of chest pain in an infected patient should not be underestimated and should lead to prompt investigations for myocarditis. Monkeypox infection should also be included in the differential diagnosis of myocarditis, particularly in at-risk patients such as men who have sex with men with multiple partners in whom complete examination for skin or mucosal lesions should thus be performed.
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- Association of In Utero Antipsychotic Medication Exposure With Risk of Congenital Malformations in Nordic Countries and the US. [Journal Article]JAMA Psychiatry. 2023 Feb 01; 80(2):156-166.JP
- CONCLUSIONS: In this study, considering the evidence from primary and sensitivity analyses and inevitable statistical noise for very rare exposure-outcome combinations, in utero antipsychotic exposure generally was not meaningfully associated with an increased risk of malformations. The observed increased risks of oral clefts associated with olanzapine, gastroschisis, and other specific brain anomalies with atypical antipsychotics and cardiac malformations with chlorprothixene requires confirmation as evidence continues to accumulate.
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- [Expert consensus on clinical application of Fufang Jingjie for Fumigation and Washing]. [Journal Article]Zhongguo Zhong Yao Za Zhi. 2022 Nov; 47(21):5961-5964.ZZ
- Fufang Jingjie for Fumigation and Washing is one of the commonly used and effective drugs for external fumigation and washing of traditional Chinese medicine, it has the functions of dispelling wind, drying and dampness, alleviating edema, and reducing swelling, relieving pain and relieving itching. It is widely used for the treatment of external hemorrhoids, mixed hemorrhoids, internal hemorrhoi…
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- Efficacy of oral fecal microbiota transplantation in recurrent bowel disease: A protocol for systematic review and meta-analysis. [Journal Article]
- CONCLUSIONS: This systematic review evaluated the efficacy and safety of oFMT in the treatment of RBD to provide more comprehensive evidence.
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- StatPearls: Pudendal Nerve Block [BOOK]StatPearls. StatPearls Publishing: Treasure Island (FL)BOOK
- Pudendal nerve block (PNB) is the method of choice utilized for diagnosis and management of chronic pelvic pain caused by pudendal neuralgia, commonly due to pudendal nerve entrapment. Additionally, a pudendal nerve block is a widely used regional anesthesia technique performed for gynecology, obstetrics, and anorectal procedures.
- Slow, deep breathing intervention improved symptoms and altered rectal sensitivity in patients with constipation-predominant irritable bowel syndrome. [Journal Article]
- CONCLUSIONS: We found that a 6-week SDB intervention improved symptoms and altered rectal sensation in IBS-C patients. Moreover, SDB enhanced vagal activity. These findings suggest that the effect of SDB on IBS-C may be due to mechanisms involving autonomic responses.
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- Safety and efficacy of endoscopic ultrasound as a diagnostic and therapeutic tool in pediatric patients: a multicenter study. [Journal Article]
- CONCLUSIONS: Standard linear EUS equipment and accessories can be used safely and effectively in selected pediatric patients for diagnostic and therapeutic purposes.
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- Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series. [Case Reports]
- Between May and November, 2022, global outbreaks of human monkeypox virus infection have been reported in more than 78 000 people worldwide, predominantly in men who have sex with men. We describe the epidemiological and clinical characteristics of monkeypox virus infection in cisgender (cis) and transgender (trans) women and non-binary individuals assigned female sex at birth to improve identifi…
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- Monkeypox. [Review]
- Monkeypox is a zoonotic illness caused by the monkeypox virus, an Orthopoxvirus in the same genus as the variola, vaccinia, and cowpox viruses. Since the detection of the first human case in the Democratic Republic of the Congo in 1970, the disease has caused sporadic infections and outbreaks, mainly restricted to some countries in west and central Africa. In July, 2022, WHO declared monkeypox a …
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- Effects of Huhuang Burn Liniment on wound healing and changes in IL-10 and MMP-9 levels in patients with mixed hemorrhoids. [Journal Article]
- CONCLUSIONS: The application of Huhuang Burn Liniment in patients with mixed hemorrhoids after surgery could promote wound healing and anal function, reduce trauma pain, exudation and edema, and improve quality of life.
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- PAIN SYNDROME IN PATIENTS AFTER COMBINED OPERATIONS FOR COMBINED ANORECTAL DISEASES USING MODERN SURGICAL TECHNOLOGIES. [Journal Article]Wiad Lek. 2022; 75(9 pt 2):2238-2243.WL
- CONCLUSIONS: Conclusions: Using of radio-wave surgery device and high-frequency electrosurgery devices is much better compared to the use of a surgical metal scalpel because they cause much less pain due to the formation of a thin layer of coagulation necrosis, promoting the formation of a delicate elastic scar and preventing formation of scar anal strictures.
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- Optimisation of treatments for oral Neisseria gonorrhoeae infection: Pharmacokinetics Study (STI-PK project) - study protocol for non-randomised clinical trial. [Clinical Trial]
- Neisseria gonorrhoeae infections are common and incidence increasing. Oropharyngeal infections are associated with greater treatment failure compared with other sites and drive transmission to anogenital sites through saliva. Gonococcal resistance is increasing and new treatments are scarce, therefore, clinicians must optimise currently available and emerging treatments in order to have efficacio…
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