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(Anorexia poor appetite )
223 results
  • Assessment and Management of Appetite Loss in Older Adults: An ICFSR Task Force Report. [Journal Article]
    J Frailty Aging. 2023; 12(1) Souto Barreto P, Cesari M, … Fielding RA
  • The Appetite loss in older people is an important unmet clinical need in geriatrics. The International Conference on Frailty and Sarcopenia Research (ICFSR) organized a Task Force on April 20th 2022, in Boston, to discuss issues related to appetite loss in older people, in particular, the assessment tools currently available, its evaluation in the primary care setting, and considerations about it…
  • Inflammation as a Therapeutic Target in Cancer Cachexia. [Review]
    Cancers (Basel). 2022 Oct 26; 14(21)Clamon G, Byrne MM, Talbert EE
  • Cachexia is a common complication of cancer and is associated with poor quality of life and a decrease in survival. Many patients with cancer cachexia suffer from inflammation associated with elevated cytokines, such as interleukin-1beta (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor (TNF). Single-agent trials to treat cancer cachexia have not led to substantial benefit as the type of c…
  • Healthy aging and chronic kidney disease. [Journal Article]
    Kidney Res Clin Pract. 2022 Nov; 41(6):644-656.Merchant RA, Vathsala A
  • The world population is aging and the prevalence of noncommunicable diseases such as diabetes, hypertension, and chronic kidney disease (CKD) will increase significantly. With advances in medical treatment and public health, the human lifespan continues to outpace the health span in such a way that the last decade of life is generally spent in poor health. In 2015, the World Health Organization d…
  • Appetite stimulants for people with cystic fibrosis. [Review]
    Cochrane Database Syst Rev. 2022 09 23; 9:CD008190.McTavish D, Thornton J
  • Chronic loss of appetite in cystic fibrosis concerns both individuals and families. Appetite stimulants have been used to help cystic fibrosis patients with chronic anorexia attain optimal body mass index (BMI) and nutritional status. However, these may have adverse effects on clinical status. This is an updated version of the original review.
  • [Development of Therapy for Cancer Cachexia in Pancreatic Cancer]. [Journal Article]
    Gan To Kagaku Ryoho. 2022 Jul; 49(7):728-731.Mitsunaga S
  • Cancer cachexia is a metabolic disorder syndrome that causes skeletal muscle loss and progressive physical dysfunction, which is observed in more than half of patients with advanced pancreatic cancer. Cancer cachexia is considered to be associated with poor prognosis, worsening adverse events, decreased treatment compliance, and decreased treatment efficacy. The ghrelin receptor agonist leads ske…
  • Current Screening Methods for the Risk or Presence of Malnutrition in Cancer Patients. [Review]
    Cancer Manag Res. 2022; 14:561-567.Molfino A, Imbimbo G, Laviano A
  • Malnutrition is highly common among cancer patients and is associated with a poor quality of life, increased treatment toxicities and decreased survival. The screening of malnutrition should be performed in an early stage of cancer disease and should be rapid, not expensive and highly sensitive to identify the risk of developing malnutrition. Importantly, international clinical guidelines suggest…
  • Primary Adrenal Lymphoma: Two Case Series From China. [Journal Article]
    Front Endocrinol (Lausanne). 2021; 12:778984.Zeng J, Yan F, … Yang G
  • CONCLUSIONS: PAL is a rare disease. The clinical characteristics of PAL include loss of appetite and weight loss. Endocrine evaluation should be performed to determine whether patients have adrenal insufficiency, especially patients with bilateral lesions. FDG-PET appears to be more accurate than other imaging modalities in revealing extra-adrenal sites. Better therapy is required to improve the poor prognosis of PAL.
  • Poor oral health and anorexia in older rehabilitation patients. [Journal Article]
    Gerodontology. 2022 Mar; 39(1):59-66.Nomoto A, Shimizu A, … Fujishima I
  • CONCLUSIONS: Poor oral health was associated with anorexia in older inpatients. Detection of poor oral health status using a comprehensive oral health assessment may be useful for anorexic patients. Early detection for poor oral health using comprehensive oral health assessments and oral care and prosthetic treatment may be useful for anorexic patients.
  • Gastrointestinal and Liver Manifestations in COVID-19 Population. [Review]
    Middle East J Dig Dis. 2021 Oct; 13(4):281-286.Saleem S, Ishtiaq R, … Bleibel W
  • The coronavirus was first identified as the cause of pneumonia in Wuhan, a town in the Hubei Province of China, in December 2019. It usually has respiratory symptoms such as myalgia, headache, cough, and dyspnea. In the medical literature, digestive symptoms and liver disease have been reported in Coronavirus disease in 2019 (COVID-19) patients. In this review article, we summarized the recent st…
  • Review of the Effects and Safety of Traditional Chinese Medicine in the Treatment of Cancer Cachexia. [Review]
    Asia Pac J Oncol Nurs. 2021 Sep-Oct; 8(5):471-486.Xu B, Cheng Q, So WKW
  • Cancer cachexia is characterized by weight loss, anorexia, asthenia, and anemia among cancer patients and can lead to their decreased physical function, poor quality of life, and reduced survival. Progestins have been reported to have beneficial effects on appetite improvement in patients with cancer; however, serious complications have been reported as a result of their use. Traditional Chinese …
  • [The Treatment of Cancer Cachexia]. [Journal Article]
    Gan To Kagaku Ryoho. 2021 Aug; 48(8):987-991.Tanaka S, Takayama K
  • Cancer cachexia is defined as a multifactorial syndrome that causes anorexia and an ongoing loss of skeletal muscle mass (with or without loss of fat mass). When patients got cachexia, the effectiveness and tolerance for anti-cancer therapy is reduced, leading to their poor prognosis. Although known as such disease, there had been no effective cure for cancer cachexia. Ghrelin is a peptide hormon…
  • Poor nutritional status, risk of sarcopenia and nutrition related complaints are prevalent in COVID-19 patients during and after hospital admission. [Journal Article]
    Clin Nutr ESPEN. 2021 06; 43:369-376.Wierdsma NJ, Kruizenga HM, … Weijs PJ
  • CONCLUSIONS: In conclusion, one in five hospital admitted COVID-19 patients suffered from serious acute weight loss and 73% had a high risk of sarcopenia. Moreover, almost all patients had one or more nutritional complaints. Of these complaints, decreased appetite, feeling of being full, shortness of breath and changed taste and loss of taste were the most predominant nutrition related complaints. These symptoms have serious repercussions on nutritional status. Although nutritional complaints persisted a long time after discharge, only a small group of patients received dietetic treatment after hospital discharge in recovery phase. Clinicians should consider the risks of acute malnutrition and sarcopenia in COVID-19 patients and investigate multidisciplinary treatment including dietetics during hospital stay and after discharge.
  • Cancer cachexia: molecular mechanism and pharmacological management. [Review]
    Biochem J. 2021 05 14; 478(9):1663-1688.Li Y, Jin H, … Zou Z
  • Cancer cachexia often occurs in malignant tumors and is a multifactorial and complex symptom characterized by wasting of skeletal muscle and adipose tissue, resulting in weight loss, poor life quality and shorter survival. The pathogenic mechanism of cancer cachexia is complex, involving a variety of molecular substrates and signal pathways. Advancements in understanding the molecular mechanisms …
  • The composition of the gut microbiome differs among community dwelling older people with good and poor appetite. [Journal Article]
    J Cachexia Sarcopenia Muscle. 2021 04; 12(2):368-377.Cox NJ, Bowyer RCE, … Steves CJ
  • CONCLUSIONS: This study is the first to observe differences in the composition of gut microbiota between healthy community dwelling older individuals with good and poor appetite. We found female individuals with reduced muscle strength had poor appetite compared with those with normal strength. These associations require further examination to understand causality and mechanisms of interaction, to inform potential strategies targeting the gut microbiota as a novel intervention for anorexia of ageing and sarcopenia.
  • Therapeutic thoracentesis symptoms and activity: a qualitative study. [Journal Article]
    BMJ Support Palliat Care. 2021 Jan 08 [Online ahead of print]Twose C, Ferris R, … Mishra E
  • CONCLUSIONS: Overall health and respiratory symptoms improved following drainage, but constitutional symptoms did not improve. This may be because constitutional symptoms are caused by the underlying cancer. This study suggests that clinicians should consider a range of symptoms, rather than just breathlessness, in planning outcomes for clinical trials. These results are important to inform patients about the potential benefits and duration of symptom improvement after therapeutic aspiration.
  • Malnutrition in cirrhosis: More food for thought. [Review]
    World J Hepatol. 2020 Nov 27; 12(11):883-896.Chapman B, Sinclair M, … Testro AG
  • Malnutrition is highly prevalent in liver cirrhosis and its presence carries important prognostic implications. The clinical conditions and pathophysiological mechanisms that cause malnutrition in cirrhosis are multiple and interrelated. Anorexia and liver decompensation symptoms lead to poor dietary intake; metabolic changes characterised by elevated energy expenditure, reduced glycogen storage,…
  • Poor Appetite Is Associated with Six Month Mortality in Hospitalised Older Men and Women. [Journal Article]
    J Nutr Health Aging. 2020; 24(10):1107-1110.Cox NJ, Er Lim S, … Robinson SM
  • CONCLUSIONS: Poor appetite is common in hospitalised older people. We have confirmed the association, previously reported in older women, between poor appetite during hospital stay and greater mortality at six months post-discharge but in a larger study including older men and women. Further research is needed to understand the mechanisms of poor appetite, which lead to increased mortality.
  • Pharmacist's Intervention Considering the Prognosis for a Terminal Cancer Patient: A Case Report. [Case Reports]
    Pharmacy (Basel). 2020 Nov 11; 8(4)Okada M, Okazaki K, … Sugihara N
  • Prognostic prediction has been reported to affect the decision of doctors and non-physician health care providers such as nurses, social workers, pastors, and hospice volunteers on the selection of appropriate medical interventions. This was a case of a 65-year-old woman who presented with a poor oral intake. The patient had a history of sigmoid colon cancer with abdominal wall metastasis and per…
  • COVID-19, nausea, and vomiting. [Review]
    J Gastroenterol Hepatol. 2021 Mar; 36(3):646-656.Andrews PLR, Cai W, … Sanger GJ
  • Exclusion of nausea (N) and vomiting (V) from detailed consideration as symptoms of COVID-19 is surprising as N can be an early presenting symptom. We examined the incidence of NV during infection before defining potential mechanisms. We estimate that the overall incidence of nausea (median 10.5%), although variable, is comparable with diarrhea. Poor definition of N, confusion with appetite loss,…
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