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Unbound Medicine.
(Anorexia nervosa)
18,795 results
  • Atypical anorexia nervosa: Implications of clinical features and BMI cutoffs. [Journal Article]
    Int J Eat Disord. 2023 Feb 05 [Online ahead of print]Kim YR, An Z, Treasure J
  • Atypical anorexia nervosa (atypical AN) appears to be a heterogeneous disorder under the current diagnostic system. Though the body mass index (BMI) cutoff point of 18.5 kg/m2 is a criterion that distinguishes atypical AN from AN, the cutoff may not be universally applicable as the norms for BMI vary and can be affected by several factors, including cross-country differences and social determinan…
  • An examination of eating disorder fears in imaginal exposure scripts. [Journal Article]
    J Affect Disord. 2023 Feb 02; 326:163-167.Butler RM, Williams B, Levinson CA
  • CONCLUSIONS: Imaginal exposure scripts contained a large number of fears related to food, weight/shape, judgment, and loss of control, among others. These findings extend the current understanding of ED fears and provide evidence for the individualized and varied nature of fears. Identification of ED fears can further inform research on designing personalized, exposure-based treatment approaches.
  • Personalizing eating disorder treatment using idiographic models: An open series trial. [Journal Article]
    J Consult Clin Psychol. 2023 Jan; 91(1):14-28.Levinson CA, Williams BM, … Ralph-Nearman C
  • CONCLUSIONS: These data suggest that network-informed personalized treatment has high acceptability and feasibility and can decrease ED and related pathology, possibly serving as a feasible alternative to existing treatments. Future randomized controlled trials comparing network-informed personalized treatment for ED to existing gold standard treatments are needed. Additionally, more research is needed on this type of personalized treatment both in the EDs, as well as in additional forms of psychopathology, such as depression. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
  • Neural correlates of a mindfulness-based intervention in anorexia nervosa. [Journal Article]
    BJPsych Open. 2023 Feb 02; 9(1):e22.Noda T, Isobe M, … Murai T
  • We examined the neural underpinnings of the effects of mindfulness on anxiety in anorexia nervosa using functional magnetic resonance imaging in 21 anorexia patients. We used a functional magnetic resonance imaging task designed to induce weight-related anxiety and asked participants to regulate their anxiety either using or not using an acceptance strategy. Our results showed reduced activity in…
  • What to do about atypical anorexia nervosa? Commentary on Walsh et al. (2023). [Journal Article]
    Int J Eat Disord. 2023 Feb 01 [Online ahead of print]First MB
  • Changes made to the DSM Eating Disorders over the years have aimed to reduce the prevalence of the residual DSM Eating Disorder categories (e.g., Other Specified Eating Disorder). Atypical Anorexia Nervosa (AN), included since DSM-IV as an example of a presentation not meeting criteria for a specific eating disorder, appears to be more prevalent than AN. It is defined as meeting all of the criter…
  • Assessment and management of cardiovascular complications in eating disorders. [Review]
    J Eat Disord. 2023 Jan 30; 11(1):13.Friars D, Walsh O, McNicholas F
  • CONCLUSIONS: The cardiovascular complications in EDs are primarily linked to malnutrition, and patients presenting with Anorexia Nervosa are most often at greatest risk of structural and functional cardiac abnormalities, including aberrations of heart rate and rhythm, haemodynamic changes and peripheral vascular abnormalities. Other cardiovascular abnormalities are secondary to electrolyte imbalances, as seen in patients with Bulimia Nervosa. More recently defined EDs including Avoidant/Restrictive Food Intake Disorder and Binge Eating Disorder are also likely associated with distinct cardiovascular complications though further research is required to clarify their nature and severity. Most cardiovascular abnormalities are fully reversible with nutritional restoration, and normalisation of eating behaviours, including the cessation of purging, though rare cases are linked to cardiac deaths. A detailed clinical enquiry accompanied by a thorough physical examination is imperative to ensure the medical safety of AYAs with EDs, and should be supported by an electrocardiogram and laboratory investigations. Consideration of cardiovascular issues, along with effective collaboration with acute medical teams allows community clinicians identify those at highest risk and minimise adverse outcomes in this cohort.
  • Pulmonary complications of eating disorders: a literature review. [Review]
    J Eat Disord. 2023 Jan 30; 11(1):12.Nitsch A, Kearns M, Mehler P
  • The medical complications of eating disorders (EDs) have been described in the literature; however, the pulmonary system has historically been described as relatively spared from the ravages of eating disorders and thus neglected in the literature. Here we review the pulmonary complications that have been described in the literature, including the effects of starvation on the lungs of nutritional…
  • Temporal dynamics of cognitive flexibility in adolescents with anorexia nervosa: a high-density EEG study. [Journal Article]
    Eur J Neurosci. 2023 Jan 22 [Online ahead of print]Berchio C, Clémentine Annen L, … Micali N
  • Impairment in cognitive flexibility is a core symptom of anorexia nervosa (AN) and is associated with treatment resistance. Nevertheless, studies on the neural basis of cognitive flexibility in adolescent AN are rare. This study aimed to investigate brain networks underlying cognitive flexibility in adolescents with AN. To address this aim, participants performed a Dimensional Change Card Sorting…
  • Ketamine and Zinc: Treatment of Anorexia Nervosa Via Dual NMDA Receptor Modulation. [Review]
    CNS Drugs. 2023 Jan 22 [Online ahead of print]Mitchell JS, Hermens DF, … Lagopoulos J
  • Anorexia nervosa is a disorder associated with serious adverse health outcomes, for which there is currently considerable treatment ineffectiveness. Characterised by restrictive eating behaviours, distorted body image perceptions and excessive physical activity, there is growing recognition anorexia nervosa is associated with underlying dysfunction in excitatory and inhibitory neurometabolite met…
  • Hair-Based Assessment of Sex Steroid Hormones in Patients with Anorexia Nervosa. [Journal Article]
    Metabolites. 2022 Dec 22; 13(1)Batury VL, Tam FI, … Ehrlich S
  • Anorexia nervosa (AN) is a complex psychiatric disorder accompanied by a variety of endocrine effects. Altered levels of the sex steroid hormones progesterone and dehydroepiandrosterone (DHEA) have been shown to occur in patients with AN using short-term hormonal measurement methods based on blood, saliva, and urine samples. However, since sex steroid hormone levels fluctuate during the menstrual…
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