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(Antidotes cyanide)
1,710 results
  • Oral Glycine and Sodium Thiosulfate for Lethal Cyanide Ingestion. [Journal Article]
  • JCJ Clin Toxicol 2017; 7(3)
  • Brenner M, Azer SM, … Boss GR
  • CONCLUSIONS: Oral sodium thiosulfate with gastric alkalization rescued animals from lethal doses of ingested cyanide. The combination of oral glycine and sodium thiosulfate may have potential for treating high dose acute cyanide ingestion and merits further investigation. The combination of systemic and oral therapy may provide further options.
  • Intraosseous administration of antidotes - a systematic review. [Review]
  • CTClin Toxicol (Phila) 2017; 55(10):1025-1054
  • Elliott A, Dubé PA, … Gosselin S
  • CONCLUSIONS: The evidence supporting the use of IO route for the administration of antidotes in a context of poisoning is scarce. The majority of the evidence consists of case reports and animal experiments. Common antidotes such as acetylcysteine, fomepizole, and digoxin-specific antibody fragments have not been studied or reported with the use of the IO route. Despite the low-quality evidence available, IO access is a potential option for antidotal treatments in toxicological resuscitation when IV access is unavailable.
  • Suicide attempt with acetonitrile ingestion in a nursing mother. [Case Reports]
  • CTClin Toxicol (Phila) 2017; 55(8):929-933
  • De Capitani EM, Borrasca-Fernandes CF, … Costa JL
  • CONCLUSIONS: The clinical management must involve the use of CN antidotes for more than 24 h depending on the symptoms and blood levels of ACN. Furthermore, our data showed the possible existence of a close relationship between plasma and breast milk levels.
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