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(Antimetabolites)
371,703 results
  • Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults. [Randomized Controlled Trial]
  • NEJMN Engl J Med 2018 08 02; 379(5):440-453
  • Menzies D, Adjobimey M, … Benedetti A
  • CONCLUSIONS: The 4-month regimen of rifampin was not inferior to the 9-month regimen of isoniazid for the prevention of active tuberculosis and was associated with a higher rate of treatment completion and better safety. (Funded by the Canadian Institutes of Health Research and the Australian National Health and Medical Research Council; ClinicalTrials.gov number, NCT00931736 .).
  • Safety and Side Effects of Rifampin versus Isoniazid in Children. [Randomized Controlled Trial]
  • NEJMN Engl J Med 2018 08 02; 379(5):454-463
  • Diallo T, Adjobimey M, … Menzies D
  • CONCLUSIONS: Among children under the age of 18 years, treatment with 4 months of rifampin had similar rates of safety and efficacy but a better rate of adherence than 9 months of treatment with isoniazid. (Funded by the Canadian Institutes of Health Research and Conselho Nacional de Pesquisa; ClinicalTrials.gov number, NCT00170209 .).
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