- COVID-19-associated mental health impact on menstruation physiology: A survey study among medical students in Jordan. [Journal Article]Womens Health (Lond). 2023 Jan-Dec; 19:17455057221150099.WH
- CONCLUSIONS: This study revealed that the stress related to the pandemic of coronavirus disease 2019 could affect the female menstrual cycle and hence the quality of women's life. Therefore, this study could serve as a baseline for planning and introducing stress mitigation interventions in crisis situations to improve the physiological and mental well-being of females and improve their quality of life.
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- Clinical profile of dermatitis neglecta with special emphasis on psychiatric comorbidities: A case series of 22 patients from Eastern India. [Case Reports]Indian J Psychiatry. 2022 Nov-Dec; 64(6):599-604.IJ
- Dermatitis neglecta (DN), first described by Poskitt et al. in 1995, is a dermatosis resulting from insufficient frictional cleansing of the skin. Lesions result from self-neglect and may have several underlying etiologies, including psychiatric conditions. There is a dearth of any formal study or large case series on this subject. Moreover, the psychological aspects of DN mostly remain unexplore…
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- Toward a causal model of chronic back pain: Challenges and opportunities. [Review]Front Comput Neurosci. 2022; 16:1017412.FC
- Chronic low back pain (cLBP) afflicts 8. 2% of adults in the United States, and is the leading global cause of disability. Neuropsychiatric co-morbidities including anxiety, depression, and substance abuse- are common in cLBP patients. In particular, cLBP is a risk factor for opioid addiction, as more than 50% of opioid prescriptions in the United States are for cLBP. Misuse of these prescription…
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- Characteristics of menstrual cycle disorder and saliva metabolomics of young women in a high-temperature environment. [Journal Article]Front Physiol. 2022; 13:994990.FP
- Objective: Menstrual disorders induced by high-temperature environments, can seriously damage women's reproductive health and workability. The regulation mechanism underlying it is not yet to be elucidated. Saliva is an information-rich biological fluid that can reflect systemic diseases. Here, we investigated the characteristics of menstrual cycle disorders and saliva metabolomics to provide a d…
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- Impact of Childhood Trauma and Adult Separation Anxiety Disorder on Quality of Life in Individuals with Schizophrenia. [Journal Article]Neuropsychiatr Dis Treat. 2023; 19:181-196.ND
- CONCLUSIONS: Childhood trauma predicts adult separation anxiety disorder, which partially mediates the impact of childhood trauma on quality of life in individuals with schizophrenia. Therapeutic interventions for adult separation anxiety disorder in individuals with schizophrenia and a history of childhood trauma may help increase their quality of life.
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- Long-Term Effects of Anxiety on the Metabolic Control of Recently Diagnosed Type 2 Diabetes Patients: Results from the CAIPaDi Cohort Study. [Journal Article]Neuropsychiatr Dis Treat. 2023; 19:197-207.ND
- CONCLUSIONS: Patients with AXD had the worst glycemic control at 3 and 12 months of follow-up. HbA1c differences in patients with AXD compared with non-AXD subjects increases over time in association with anxiety symptoms.
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- Exploring the research landscape of the past, present, and future of thyroid nodules. [Journal Article]Front Med (Lausanne). 2022; 9:831346.FM
- CONCLUSIONS: Basic research on thyroid nodules has unmet research requirements. Future research could focus on developing strategies to more efficiently identify malignant nodules, exploring the mechanism of thyroid nodule development, and enhancing the quality of life of thyroid patients.
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- Desynchronized white matter function and structure in drug-naive first-episode major depressive disorder patients. [Journal Article]Front Psychiatry. 2022; 13:1082052.FP
- CONCLUSIONS: Our results indicated that WM dysfunction may be associated with the pathophysiological mechanism of depression. Our study also suggested that the functional damage of the WM may precedes the structural damage in first-episode MDD patients. Furthermore, for mental disorders, slow-5 frequency band may be a more sensitive functional indicator for early detection of abnormal spontaneous brain activity in WM.
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- Changes in psychological and cognitive variables as well as cortisol levels in recovered Covid-19 patients: a longitudinal study. [Journal Article]Curr Psychol. 2023 Jan 25 [Online ahead of print]CP
- CONCLUSIONS: Improvement of cognitive functioning was in line with the increase in cortisol. Besides, the decrease in mental health had no effect on the cognitive functioning.
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- Genome-wide association study in a rat model of temperament identifies multiple loci for exploratory locomotion and anxiety-like traits. [Journal Article]Front Genet. 2022; 13:1003074.FG
- Common genetic factors likely contribute to multiple psychiatric diseases including mood and substance use disorders. Certain stable, heritable traits reflecting temperament, termed externalizing or internalizing, play a large role in modulating vulnerability to these disorders. To model these heritable tendencies, we selectively bred rats for high and low exploration in a novel environment [bred…
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- The Development of Psychiatric Illness and Chemoprophylaxis of Botulinum Toxin in Migraine: A Narrative Review. [Review]Cureus. 2022 Dec; 14(12):e32998.C
- A migraine is not just a headache. It is an extremely prevalent neurological condition marked by periodic episodes of unilateral headache, with more than 10 million cases yearly. Migraine often begins at the age of puberty. It substantially impacts the brain and, consequently, psychiatric behavior linked with frequent migraine attacks that may be moderate to severe in intensity. A crucial aspect …
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- Explaining the Psychological Distress of Women with High-Risk Pregnancies in Iran: A Qualitative Study. [Journal Article]Iran J Nurs Midwifery Res. 2022 Nov-Dec; 27(6):560-566.IJ
- CONCLUSIONS: This study highlighted a wide range of psychosocial factors involved in the PD of women with HRP. These findings can be used to design appropriate prevention strategies to manage the mental health problems of these women in order to turn their pregnancy into a pleasurable experience.
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- The impact of social-relationship patterns on worsening mental health among the elderly during the COVID-19 pandemic: Evidence from Hungary. [Journal Article]SSM Popul Health. 2023 Mar; 21:101346.SP
- Evidence indicates the coronavirus pandemic has severely affected the oldest age group: in Hungary 92.7 per cent of those who died due to COVID-19 infection were 60 years of age or older. The age structure of the deceased was very similar in other countries. As, due to their underlying health status, elderly people are more vulnerable to the serious diseases caused by the coronavirus, strict gove…
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- Life-years lost associated with mental illness: a cohort study of beneficiaries of a South African medical insurance scheme. [Preprint]medRxiv. 2023 Jan 19M
- People with mental illness have a reduced life expectancy, but the extent of the mortality gap and the contribution of natural and unnatural causes to excess mortality among people with mental illness in South Africa are unknown.
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- Genetic liability to major psychiatric disorders contributes to multi-faceted quality of life outcomes in children and adults. [Preprint]medRxiv. 2023 Jan 18M
- CONCLUSIONS: The present study reveals an inverse relationship between psychiatric genetic liabilities and multiple quality of life metrics, with ADHD-associated genetic risk being the main contributor in both children and adults, and MDD additionally showing effects in adults. All effect sizes observed were small, as expected. Understanding potential real-world outcomes of quantitative measures of disorder-related genetic risks in the general population can provide a scientific foundation for societal intervention and policy-making processes, with profound implications for promoting a flourishing society.
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- Implantable flexible multielectrode arrays for multi-site sensing of serotonin tonic levels. [Preprint]bioRxiv. 2023 Jan 20B
- Real-time multi-channel measurements of tonic serotonin (5-hydroxytryptamine, 5-HT) concentrations across different brain regions are of utmost importance to the understanding of 5-HT’s role in anxiety, depression, and impulse control disorders, which will improve the diagnosis and treatment of these neuropsychiatric illnesses. Chronic sampling of 5-HT is critical in tracking disease developmen…
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- Vigilance or avoidance: How do autistic traits and social anxiety modulate attention to the eyes? [Journal Article]Front Neurosci. 2022; 16:1081769.FN
- Social anxiety disorder (SAD) and autism spectrum disorder (ASD) are highly overlapping in symptoms and have a high rate of comorbidity, posing challenges in diagnosis and intervention for both disorders. Both disorders are linked to abnormal attention to the eyes, yet how they interactively modulate the attentional process to the eyes remains unclear.
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- Behavioral lateralization of mice varying in serotonin transporter genotype. [Journal Article]Front Behav Neurosci. 2022; 16:1095567.FB
- In humans, non-right-handedness is associated with a higher incidence of psychiatric disorders. Since serotonin seems to be involved in both, the development of psychiatric disorders and lateralization, the present study focuses on the effect of the serotonin transporter (5-HTT) gene on behavioral lateralization. For this, we used the 5-HTT knockout mouse model, a well-established animal model fo…
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- Adolescents at risk of eating disorders: The mediating role of emotional distress in the relationship between differentiation of self and eating disorders. [Journal Article]Front Psychol. 2022; 13:1015405.FP
- CONCLUSIONS: It is concluded that high DoS may reduce emotional distress, which may, in turn, decrease the risk of EDs. In addition, the results enable an in-depth understanding of specific risk factors of EDs that characterize each sex.
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- Anxiety, depression, and academic stress among medical students during the COVID-19 pandemic. [Journal Article]Front Psychol. 2022; 13:1066673.FP
- CONCLUSIONS: There was a relevant impact of the mandatory lockdown during COVID-19 pandemic on the mental health of medical students reflected in the high prevalence rates of anxiety, depression, and stressors in the studied population pointing to the need for designing and implementing preventive strategies to deal with the effects of lockdowns.
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- Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress. [Journal Article]J Neuroinflammation. 2023 Jan 30; 20(1):16.JN
- Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS). Anxiety and depression are the most common psychiatric comorbidities of MS, which seriously affect patients' quality of life, treatment compliance, and prognosis. However, current treatments for anxiety and depression in MS show low therapeutic efficacy and significant side effects. In the present …
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- Mediators of Improved PTSD Symptoms in Veterans and Civilians Following a Yoga Program. [Journal Article]Acta Neuropsychiatr. 2023 Jan 30 [Online ahead of print]AN
- CONCLUSIONS: Investigation of mental well-being and mental illness stigma as potential mediators is warranted in future studies of yoga as a treatment for PTSD as they may prove to be important foci for yoga interventions.
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- Cardiac interoception in patients accessing secondary mental health services: A transdiagnostic study. [Journal Article]Auton Neurosci. 2023 Jan 13; 245:103072.AN
- CONCLUSIONS: The multilevel characterisation presented here identified certain physiological and interoceptive differences associated with psychiatric symptoms and diagnoses. The clinical stratification and therapeutic targeting of interoceptive mechanisms is therefore of potential value in treating certain psychiatric conditions.
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- Feasibility, acceptability and practicality of transcranial stimulation in obsessive compulsive symptoms (FEATSOCS): A randomised controlled crossover trial. [Journal Article]Compr Psychiatry. 2023 Jan 26; 122:152371.CP
- CONCLUSIONS: tDCS was acceptable, practicable to apply, well-tolerated and appears a promising potential treatment for OCD. The L-OFC represents the most promising target based on clinical changes, though the effects on OCD symptoms were not statistically significant compared to sham. SMA stimulation showed lesser signs of promise. Further investigation of tDCS in OCD is warranted, to determine the optimal stimulation protocol (current, frequency, duration), longer-term effectiveness and brain-based mechanisms of effect. If efficacy is substantiated, consideration of home-based approaches represents a rational next step.
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- The prevalence of mental ill-health in women during pregnancy and after childbirth during the Covid-19 pandemic: a systematic review and Meta-analysis. [Journal Article]BMC Pregnancy Childbirth. 2023 Jan 28; 23(1):76.BP
- CONCLUSIONS: It is important to note that studies included in this review used a range of outcome measures which does not allow for direct comparisons between findings. Most studies reported self-reported measure of symptoms without clinical diagnoses so conclusions can be made for symptom prevalence rather than of mental illness. The importance of managing mental health during pregnancy and after-delivery improves the quality of life and wellbeing of mothers hence developing an evidence-based approached as part of pandemic preparedness would improve mental health during challenging times.
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- Examining the description of the concept "treatment as usual" for patients with depression, anxiety and stress-related mental disorders in primary health care research - A systematic review. [Review]J Affect Disord. 2023 Jan 25; 326:1-10.JA
- CONCLUSIONS: The current study provides an assessment tool with three classification levels for TAU. The description of TAU is still insufficient in RCT studies conducted in primary care, which may affect the interpretation of results. In future research a detailed description of TAU is recommended.
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- Clinical characteristics of late-onset neuromyelitis optica spectrum disorder. [Journal Article]Mult Scler Relat Disord. 2023 Jan 15; 70:104517.MS
- CONCLUSIONS: LO-NMOSD patients have worse prognoses than those of EO-NMOSD patients. Higher AQP4-IgG titers, more WMHs, thoracic myelitis, and severe sensory symptoms are associated with cognition, depression, anxiety, and sleep disorders.
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- Curcumin Ameliorates Neurobehavioral Deficits in Ambient Dusty Particulate Matter-Exposure Rats: The Role of Oxidative Stress. [Journal Article]Neurochem Res. 2023 Jan 28 [Online ahead of print]NR
- It has been consistently found that exposure to ambient air pollution, such as particulate matter (PM), results in cognitive impairments and mental disorders. This study aimed to investigate the possible neuroprotective effects of curcumin, a polyphenol compound, on the neurobehavioral deficits and to identify the role of oxidative stress in dusty PM exposure rats. Rats received curcumin (50 mg/k…
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- Psychological distress and coping orientations in young adults: their associations with temporomandibular disorder symptoms. [Journal Article]Acta Odontol Scand. 2023 Jan 28 [Online ahead of print]AO
- CONCLUSIONS: Asian young adults with CT and PT had significantly higher levels of negative affectivity, anxiety and stress than their counterparts with IT and/or NT. Negative affectivity/emotions were associated with the use of dysfunctional coping strategies and anxiety was the main psychological risk factor for TMD symptoms.
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- The relationship between psychosocial and psychiatric risk factors and poor long term outcome following mild traumatic brain injury: a systematic review. [Review]Eur J Neurol. 2023 Jan 27 [Online ahead of print]EJ
- CONCLUSIONS: Early psychological and psychiatric factors may negatively interact with recovery potential to increase the risk of chronicity of PPCS burden after mTBI. This opens opportunities for research on screening tools and early intervention in patients at risk.
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