- Dilating Vascular Diseases: Pathophysiology and Clinical Aspects. [Review]
- IJInt J Vasc Med 2018; 2018:9024278
- Atherosclerotic disease of the vessels is a significant problem affecting mortality and morbidity all over the world. However, dilatation of the vessels either in the arterial system or in the venous...
Atherosclerotic disease of the vessels is a significant problem affecting mortality and morbidity all over the world. However, dilatation of the vessels either in the arterial system or in the venous territory is another vessel disease. Varicocele, pelvic, and peripheral varicose veins and hemorrhoids are aneurysms of the venous vascular regions and have been defined as dilating venous disease, recently. Coronary artery ectasia, intracranial aneurysm, and abdominal aortic aneurysm are examples of arterial dilating vascular diseases. Mostly, they have been defined as variants of atherosclerosis. Although there are some similarities in terms of pathogenesis, they are distinct from atherosclerotic disease of the vessels. In addition, pathophysiological and histological similarities and clinical coexistence of these diseases have been demonstrated both in the arterial and in the venous system. This situation underlies the thought that dilatation of the vessels in any vascular territory should be considered as a systemic vessel wall disease rather than being a local disease of any vessel. These patients should be evaluated for other dilating vascular diseases in a systematic manner.
- Increasing Incidence of Thoracic Aortic Aneurysm Repair in Germany in the Endovascular Era: Secondary Data Analysis of the Nationwide German DRG Microdata. [Journal Article]
- EJEur J Vasc Endovasc Surg 2018 Sep 13
- CONCLUSIONS: Eighty per cent of patients treated surgically for a dTAA receive endovascular therapy, with low peri-operative mortality in non-ruptured cases. Elective endovascular repair should be considered for individuals at a high risk of rupture who are fit for surgery. Open repair, increased age, and a high comorbidity score are associated with higher mortality.
- Combined Type III and Type II Endoleak after EVAR. Presentation of two Cases and Literature Review. [Journal Article]
- AVAnn Vasc Surg 2018 Sep 12
- Although endovascular aneurysm repair (EVAR) is a feasible option for high risk patients resulting in lower perioperative mortality when compared with open repair, the need for re-intervention and lo...
Although endovascular aneurysm repair (EVAR) is a feasible option for high risk patients resulting in lower perioperative mortality when compared with open repair, the need for re-intervention and long-term follow-up affects its use. The aim of the current report is to present two cases of patients with Type IIIa endoleak from limb disconnection (one patient with double-bilateral endoleak) combined with a late Type II endoleak and symptomatic sac growth treated in our department. We also perform a literature review about Type III endoleaks and their treatment options.
- Use of 3-Dimensional Printing to Create Patient-Specific Abdominal Aortic Aneurysm Models for Preoperative Planning. [Review]
- JCJ Cardiothorac Vasc Anesth 2018 Aug 09
- Fenestrated endovascular aortic repair (FEVAR) stent grafting is a minimally invasive procedure and an alternative to open surgical repair for abdominal aortic aneurysm repair, particularly with unid...
Fenestrated endovascular aortic repair (FEVAR) stent grafting is a minimally invasive procedure and an alternative to open surgical repair for abdominal aortic aneurysm repair, particularly with unideal neck anatomy. Planning and implementing a custom FEVAR graft is complicated, requiring advanced training and years of practice. As such, a method for creating a patient-specific, to-scale, cost-effective, 3-dimensional abdominal aortic aneurysm model for use in preoperative planning is presented. The model can be used to help physicians create custom FEVAR grafts, thus eliminating the currently used difficult and technical method for creating custom grafts. It also can assist physicians in visualizing and practicing their surgical approach for a specific patient.
- Operated descending thoracic and thoracoabdominal atherosclerotic aortic aneurysm prognosis. [Journal Article]
- JMJ Med Vasc 2018; 43(5):288-292
- CONCLUSIONS: Long-term prognosis of atherosclerotic DTA may be worse than that of TAAA's. This retrospective study reflects experience in the management of DTA and TAAA in a single-center. Prospective data in patients treated with endovascular procedures for DTA or TAAA, with fenesterated or branched endoprosthesis, are warranted to confirm these results.
- Variation in Surgical Treatment of Abdominal Aortic Aneurysms With Small Aortic Diameters in the Netherlands. [Journal Article]
- AnnSAnn Surg 2018 Sep 13
- CONCLUSIONS: Dutch VSUs regularly deviate from the guidelines regarding aneurysm diameter, with variation between VSUs. Consensus exists amongst VSUs on acceptable reasons for guideline deviations; however, the majority underestimates their actual deviation percentage.
- Smooth muscle-specific biomarker for abdominal aortic aneurysm: a beacon for the silent killer. [Journal Article]
- AJAm J Physiol Heart Circ Physiol 2018 Sep 14
- Effect of abdominal aortic endoprostheses on arterial pulse wave velocity in an in vitro abdominal aortic flow model. [Journal Article]
- PMPhysiol Meas 2018 Sep 14
- Aortic pulse-wave-velocity (aPWV) is a measure for arterial stiffness, which is associated with increased cardiovascular risk. Recent evidence suggests aPWV increases after endograft-placement for ao...
Aortic pulse-wave-velocity (aPWV) is a measure for arterial stiffness, which is associated with increased cardiovascular risk. Recent evidence suggests aPWV increases after endograft-placement for aortic aneurysms. The aim of this study was to investigate the influence of different aortic endoprostheses on aPWV and structural stiffness in vitro. Approach: Three different abdominal aortic endoprostheses (AFX, Endurant II, and Nellix) were implanted in identical silicone aneurysm models. One model was left untreated, and another model contained an aortic tube graft (Gelweave). The models were placed in an in vitro flow set-up that mimics physiological flow. aPWV was measured as the transit time of the pressure wave over the flow trajectory of the suprarenal to iliac segment. Structural stiffness corrected for lumen diameter was calculated for each model. Results: aPWV was significantly lower for the control compared to the AFX, Endurant, Nellix and tube graft models (13.00±1.20, 13.40±1.17, 18.18±1.20, 16.19±1.25 and 15.41±0.87m/s, respectively (P<0.05)). Structural stiffness of the AFX model was significant lower compared to the control model (4718N/m versus 5115N/m (P<0.001), respectively), whereas all other models showed higher structural stiffness. Significance: Endograft placement resulted in a higher aPWV compared to a non-treated aortic flow model. All models showed increased structural stiffness over the flow trajectory compared to the control model, except for the AFX endoprosthesis. Future studies in patients treated with an endograft are needed to evaluate the current results in vivo.
- Mycotic Aortic Aneurysm and Infected Aortic Graft After Intravesical Bacillus Calmette-Guérin Treatment for Bladder Cancer. [Journal Article]
- VEVasc Endovascular Surg 2018 Sep 13; :1538574418800128
- Although intravesical therapy with bacillus Calmette-Guérin (BCG) has proven its efficiency in the treatment of early-stage bladder cancer, infectious complications can occur and mycotic aneurysms re...
Although intravesical therapy with bacillus Calmette-Guérin (BCG) has proven its efficiency in the treatment of early-stage bladder cancer, infectious complications can occur and mycotic aneurysms represent a rare but life-threatening complication. Here, we report the case of an aortic graft infection in a patient with abdominal aortic aneurysm who received BCG instillations for the treatment of bladder cancer. Based on the current knowledge on this rare vascular complication, we discuss factors that may have contributed to its occurrence and review issues to optimize its management and early detection.
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- Comparison of Efficacy between Ramipril and Carvedilol on Limiting the Expansion of Abdominal Aortic Aneurysm in Mouse Model. [Journal Article]
- JCJ Cardiovasc Pharmacol Ther 2018 Sep 13; :1074248418798631
- CONCLUSIONS: Ramipril and carvedilol treatment shows similar efficacy in limiting AAA expansion in mouse model. Future clinical research would be warranted to validate these results.