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Unbound Medicine.
(Apo Bromocriptine)
26 results
  • Effect of BCH 325 (Pro-D-Phe-Pro-Gly) on central dopaminergic functions. [Journal Article]
    Peptides. 1995; 16(4):635-40.Rauca C, Schröder H
  • Three behavioral models were used to characterize the pharmacological action of BCH 325 on central dopaminergic transmission. The effect of acute SC treatment with BCH 325 upon dopaminergic mechanisms affecting motor activity was studied on the climbing behavior of mice. It was shown that the beta-casomorphin analogue evoked a dose-dependent increase in apomorphine (APO)-induced hypoactivity that…
  • Ethanol acutely reduces LH and prolactin secretion: possible involvement by dopamine. [Journal Article]
    Alcohol. 1994 Mar-Apr; 11(2):105-12.Ching M, Lin YC
  • Ethanol (ETOH) administered acutely to castrate male rats caused a decline in pituitary luteinizing hormone (LH) and prolactin (PRL) secretion. This was associated with an elevation in hypothalamic and median eminence stores of dopamine (DA) that was related to the dose of alcohol given. Pituitary stalk transection (PST) resulted in a significant rise in plasma PRL levels compared to sham control…
  • Apomorphine: clinical studies on erectile impotence and yawning. [Controlled Clinical Trial]
    Prog Neuropsychopharmacol Biol Psychiatry. 1989; 13(3-4):329-39.Lal S, Tesfaye Y, … Dubrovsky B
  • 1. The erectile response to the short-acting dopamine (DA) receptor agonist, apomorphine (Apo) HCl (0.25, 0.5, 0.75 and 1.0 mg sc), and placebo was evaluated in 28 impotent patients and penile circumference monitored using a mercury strain gauge and strip chart recording. 2. A full erection (increment in penile circumference greater than 2 cm and lasting at least one minute) occurred in 17 patien…
  • Acute effects of direct dopamine agonists in the mouse behavioral despair test. [Journal Article]
    Eur J Pharmacol. 1988 Sep 13; 154(2):185-90.Duterte-Boucher D, Leclère JF, … Costentin J
  • All the dopamine agonists (apomorphine, dipropylamino-5,6-dihydroxytetrahydronaphtalene, piribedil, bromocriptine, CBM 36-733) tested in the 'behavioral despair' test performed in mice had a dose-dependent anti-immobility effect, with the exception of the D-1 dopamine agonist, SKF 38393. This effect occurred at doses that reduced locomotor activity and decreased colonic temperature. A profound hy…
  • Apomorphine-induced penile tumescence in impotent patients--preliminary findings. [Controlled Clinical Trial]
    Prog Neuropsychopharmacol Biol Psychiatry. 1987; 11(2-3):235-42.Lal S, Laryea E, … Gardiner RJ
  • Apomorphine (Apo), a short acting dopamine (DA) receptor agonist induces penile erections in normal subjects. The erectile response to one or more doses of Apo HCl (0.25, 0.5, 0.75, 1.0 mg sc) or placebo was investigated in eight impotent subjects and penile tumescence monitored using a mercury strain gauge and strip chart recording. Four patients showed a full erection with Apo and one a partial…
  • Chronic treatment with bromocriptine induces behavioral supersensitivity in rats. [Journal Article]
    Life Sci. 1986 Aug 11; 39(6):513-8.Hassan MN, Higgins D, … Fahn S
  • Chronic treatment of rotating rats with equipotent doses of the dopamine (DA) agonists apomorphine (APO), 3-(3,4-dihydroxyphenyl)-1-n-propylpyrrolidine hydrobromide (DPPP) and bromocriptine (BRO) for four weeks resulted in marked differences in rotational activity following acute administration of these agonists. Whereas chronic treatment with APO and DPPP failed to produce any significant change…
  • Differential effects on phrenic output of two dopamine agonists, apomorphine and bromocriptine. [Journal Article]
    Eur J Pharmacol. 1984 Oct 30; 106(1):69-78.Nielsen AM, Bisgard GE
  • Effects of dopamine agonists upon phrenic output were studied in decerebrate, vagotomized, paralyzed, carotid-body denervated dogs. Intravenous administration of dopamine was without effect in these dogs. Apomorphine (APO) increased phrenic minute activity while bromocriptine (BRO) decreased phrenic minute activity following intravenous injection at doses of 100 micrograms/kg for each drug. BRO-i…
  • Dopaminergic and serotonergic mediation of the discriminable effects of ergot alkaloids. [Journal Article]
    Eur J Pharmacol. 1982 Jul 30; 81(4):595-602.Holohean AM, White FJ, Appel JB
  • The involvement of dopamine (DA) and serotonin (5-HT) neuronal systems in the discriminative stimulus effects of various ergot derivatives was assessed by administering four ergots to 36 rats which had been trained to discriminate either apomorphine (APO) or d-lysergic acid diethylamide (LSD) from saline. Lergotrile, lisuride and LSD substituted for APO (0.25 mg/kg) while bromocriptine and ergono…
  • Growth hormone hyperresponsiveness to dopaminergic stimulation in Huntington's chorea. [Journal Article]
    Neuroendocrinology. 1979; 28(5):313-9.Müller EE, Parati EA, … Caraceni T
  • The effect of 3 dopamine (DA) mimetic drugs, i.e. bromocriptine (Bro), apomorphine (Apo) and L-3,4-Dihydroxpenylalanine (L-dopa), was evaluated on plasma growth hormone (GH) levels in 18 patients with Huntington's chorea (HC). 27 Nonobese hospitalized patients were used as controls. Mean baseline GH levels were not altered in patients with HC. Oral administration of Bro (2.5 mg po) or L-dopa (500…
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