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(Apo C)
2,695 results
  • Apolipoprotein C-III in triglyceride-rich lipoprotein metabolism. [Journal Article]
  • COCurr Opin Lipidol 2018; 29(3):171-179
  • Ramms B, Gordts PLSM
  • CONCLUSIONS: Novel in vivo models and APOC3 missense variants revealed unique mechanisms by which apoC-III inhibits TRL catabolism. Clinical trials with Volanesorsen, an APOC3 antisense oligonucleotide, report very promising lipid-lowering outcomes. However, future studies will need to address if acute apoC-III lowering will have the same clinical benefits as a life-long reduction.
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