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Unbound Medicine.
(Apo Cimetidine)
6 results
  • Inhibition of hepatic apolipoprotein A-I gene expression by histamine. [Journal Article]
    Eur J Pharmacol. 2018 Mar 15; 823:49-57.Haas MJ, Plazarte M, … Mooradian AD
  • In a recent high throughput analysis to identify drugs that alter hepatic apolipoprotein A-I (apo A-I) expression, histamine receptor one (H1) antagonists emerged as potential apo A-1 inducing drugs. Thus the present study was undertaken to identify some of the underlying molecular mechanisms of the effect of antihistaminic drugs on apo AI production. Apo A-I levels were measured by enzyme immuno…
  • Evaluation of antiulcer potential of Mimusops hexandra in experimental gastro duodenal ulcers. [Journal Article]
    J Complement Integr Med. 2012 Aug 10; 9:Article 18.Modi KP, Lahiri SK, … Shah MB
  • The study was aimed to investigate antiulcer effects of acetone extract and its different fractions Mimusops hexandra against experimental gastro-duodenal ulcers. 80% acetone extract of stem bark of Mimusops hexandra (Extract A, p.o.) and its different fractions namely diethyl ether (Extract A1, p.o.), ethyl acetate (Extract A2, p.o.) and aqueous (Extract A3, p.o.) were tested for the presence of…
  • Species differences in blood-mediated nitrosocimetidine denitrosation. [Journal Article]
    Cancer Res. 1987 Jan 15; 47(2):353-9.Jensen DE, Stelman GJ, Spiegel A
  • Nitrosocimetidine (NC) is the nitrosated derivative of cimetidine (Tagamet), a p.o. administered drug used widely in the treatment of stomach ulcers. NC is capable of methylating DNA in vitro and in cultured cells in a manner similar to that of the laboratory carcinogens 1-methyl-2-nitro-1-nitrosoguanidine and methylnitrosourea (MNU) and gives positive indications in short-term in vitro tests for…
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