- Comparison of the effect of ferrous sulfate and ferrous gluconate on prophylaxis of iron deficiency in toddlers 6-24 months old: A randomized clinical trial. [Journal Article]
- CONCLUSIONS: Although prophylaxis with FG led to a higher Hb and ferritin levels, our study recommended that both FG and FS supplements were effective for prophylactic use in the prevention of IDA. However, FG was more effective than FS because FG group that received FG supplementation indicated a higher Hb and ferritin levels in comparison to the FS group that received FS supplementation.
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- Fortifying jelly foods with microencapsulated anti-anaemic compounds, ferrous gluconate, ascorbic acid and folic acid. [Journal Article]
- Low ferrous iron bioavailability presents a challenge for food fortification programmes. In this study, jelly foods were fortified with spray-dried chitosan microparticles that had been loaded with ferrous gluconate (FeG) and folic acid (FA) to alleviate iron deficiency anaemia and FA deficiency anaemia, respectively. The presence of FA and ascorbic acid (AA) increased the in vitro iron bioavaila…
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- Effects of various Fe compounds on the bioavailability of Pb contained in orally ingested soils in mice: Mechanistic insights and health implications. [Journal Article]Environ Int. 2022 12; 170:107664.EI
- Reducing lead (Pb) exposure via oral ingestion of contaminated soils is highly relevant for child health. Elevating dietary micronutrient iron (Fe) intake can reduce Pb oral bioavailability while being beneficial for child nutritional health. However, the practical performance of various Fe compounds was not assessed. Here, based on mouse bioassays, ten Fe compounds applied to diets (100-800 mg F…
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- Drugs and Lactation Database (LactMed): Iron Salts [BOOK]Drugs and Lactation Database (LactMed). National Library of Medicine (US): Bethesda (MD)BOOK
- Iron is a normal component in human milk. Daily oral iron intake from prenatal vitamins or other multimineral supplements does not affect milk iron levels. Higher daily oral iron dosing has a minimal effect on milk iron levels and is not expected to cause harm to the breastfed infant if needed to treat the mother’s anemia, but it is not an adequate substitute for direct infant iron supplementatio…
- Cost-Effectiveness of Ferrous Fumarate-Folic Acid and Ferrous Gluconate-Multivitamins in a High Prevalence Area of Iron Deficiency Anemia in Indonesia. [Journal Article]
- CONCLUSIONS: The ICER was estimated to be $11.59 per QALY gained, which was highly cost-effective, according to GDP-based cost-effectiveness threshold. In addition, the utility score of women with iron deficiency anemia was considered to be the most influential factor impacting the cost-effectiveness value.
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- Combining Liquid Oral Drugs with Thickener: Compatibility and Changes in Viscosity. [Journal Article]
- Older adults with oropharyngeal dysphagia (OD) are unable to swallow pills safely, so some of them use liquid-formulated drugs mixed with thickeners to ensure safety. The aim of this study was to analyze the physical compatibility of a group of drugs with a thickener formulated with modified starch (Thick & Easy®). A secondary goal was to evaluate the amount of thickener needed to obtain the thic…
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- Attitude changes in prescribing intravenous iron supplementation in different settings at a hospital consortium in Italy. [Multicenter Study]Transfus Apher Sci. 2021 Aug; 60(4):103139.TA
- CONCLUSIONS: Intravenous iron has a major role in treating iron deficiency anaemia in several settings. Third generation compounds are paving the way to more updated and safer treatments.
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- A pilot study on secondary anemia in "frailty" patients treated with Ferric Sodium EDTA in combination with vitamin C, folic acid, copper gluconate, zinc gluconate and selenomethionine: safety of treatment explored by HRV non-linear analysis as predictive factor of cardiovascular tolerability. [Journal Article]
- CONCLUSIONS: Non-linear HRV evaluation confirmed that oral administration of Ferric Sodium EDTA, in combination with vitamin C, folic acid, copper gluconate, zinc gluconate and selenomethionine (Ferachel forte®) did not impact the cardiovascular risk, without causing adverse events typically reported with other iron supplementation therapies, both oral and intravenous.
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- The postcoital test in the development of new vaginal contraceptives†. [Review]
- Postcoital tests (PCTs) have been used for over a century in the clinical evaluation of infertile couples, and for nearly 70 years in the evaluation of new vaginal contraceptive products. PCTs have been largely replaced by more modern methods in the study of infertility, but they remain the most useful way to obtain preliminary data on the effectiveness of vaginal contraceptive products. The Worl…
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- A randomized controlled trial comparing oral and intravenous iron supplementation after Roux-en-Y gastric bypass surgery. [Randomized Controlled Trial]
- CONCLUSIONS: In women developing ID after RYGB, a single dose of intravenous FCM is more effective and better tolerated than the standard treatment with either FF or FG.
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- Monitoring oral iron therapy in children with iron deficiency anemia: an observational, prospective, multicenter study of AIEOP patients (Associazione Italiana Emato-Oncologia Pediatrica). [Clinical Trial]
- Oral ferrous salts are standard treatment for children with iron deficiency anemia (IDA). The objective of our study was to monitor oral iron therapy in children, aged 3 months-12 years, with IDA. We prospectively collected clinical and hematological data of children with IDA, from 15 AIEOP (Associazione Italiana di Ematologia ed. Oncologia Pediatrica) centers. Response was measured by the increa…
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- Influence of uniform magnetic field on physicochemical properties of freeze-thawed avocado puree. [Journal Article]
- External fields are reported to have the potential to improve the quality of food after freeze-thawing. This study investigated the effect of an oscillating magnetic field with high uniformity and multi-directions at 4 mT and 50 Hz on the freezing of avocado puree. Samples of avocado puree were placed in the central zone of three pairs of orthometric Helmholtz coils where a highly homogeneous deg…
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- Effect of processing conditions on the stability of native vitamin A and fortified retinol acetate in milk. [Journal Article]
- The objective of this investigation was to evaluate the stability of vitamin A in fortified milk which was exposed to different processing conditions viz. heat treatments (pasteurization, boiling and sterilization), light exposure treatments (1485, 2970 and 4455 lux for 2, 4, 8, 16 and 32 h) and different packaging materials (polyethylene pouches and glass bottles) and also to evaluate the effect…
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- Development of sulfur doped carbon quantum dots for highly selective and sensitive fluorescent detection of Fe2+ and Fe3+ ions in oral ferrous gluconate samples. [Journal Article]
- Sulfur-doped carbon quantum dots (S-CQDs) with stable blue fluorescence were synthesized through a facile one-step hydrothermal method by using ascorbic acid and thioglycolic acid as carbon and sulfur sources. The prepared S-CQDs exhibited a sensitive and selective response to Fe3+ ions in comparison with Fe2+ and other metal ions, In the presence of adequate H2O2, Fe2+ was completely transformed…
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- Nano-Fe3C@PGC as a novel low-cost anode electrocatalyst for superior performance microbial fuel cells. [Journal Article]
- We report a novel anode electrocatalyst, iron carbide nanoparticles dispersed in porous graphitized carbon (Nano-Fe3C@PGC), which is synthesized by facile approach involving a direct pyrolysis of ferrous gluconate and a following removal of free iron, but provides microbial fuel cells with superior performances. The physical characterizations confirm the unique configuration of iron carbide nanop…
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- A Green-Mediterranean Diet, Supplemented with Mankai Duckweed, Preserves Iron-Homeostasis in Humans and Is Efficient in Reversal of Anemia in Rats. [Randomized Controlled Trial]
- CONCLUSIONS: In humans, a green-MED low-meat diet does not impair iron homeostasis. In rats, iron derived from Mankai (a green-plant protein source) is bioavailable and efficient in reversal of anemia. This trial was registered at clinicaltrials.gov as NCT03020186.
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- Chemiluminescence in the reaction of 1,2,4,5-tetraoxanes with ferrous ions in the presence of xanthene dyes: fundamentals and perspectives of analytical applications. [Journal Article]Photochem Photobiol Sci. 2019 May 15; 18(5):1130-1137.PP
- The reaction of biologically active bridged 1,2,4,5-tetraoxanes and diperoxide of trifluoroacetone with ferrous ions in the presence of xanthenes, methylene blue and methylene green is accompanied by bright chemiluminescence (CL) caused by the emission from electronically-excited dyes. The promising perspectives for the employment of the CL method for the analytical detection of tetraoxanes were …
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- Effectiveness of AOS-iron on iron deficiency anemia in rats. [Journal Article]
- Iron deficiency anemia (IDA) is one of the most serious nutritional problems. This study aimed to evaluate the therapeutic effects of a novel agar oligosaccharide-iron complex (AOS-iron) on rats with IDA, such as iron supplementation and recovery of antioxidant ability. Eighty-four weaned male SD rats were randomly divided into a normal control group (n = 12), which was fed with a standard diet, …
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- Predicting iron absorption from an effervescent iron supplement in obese patients before and after Roux-en-Y gastric bypass: a preliminary study. [Journal Article]
- CONCLUSIONS: The iron AUC0-24h showed a negative correlation with the hepcidin concentration and TSAT of obese patients, in particular post-RYGB. Therefore, our data support the use of hepcidin concentration and TSAT to distinguish potential responders from non-responders for iron supplementation particularly post-RYGB. Additionally, this study showed that the pharmacokinetic properties of iron gluconate from an effervescent tablet were unaffected by RYGB-surgery.
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- Contributing factors to iron deficiency anemia in women in Jordan: A single-center cross-sectional study. [Journal Article]
- CONCLUSIONS: Iron deficiency anemia is caused by multiple factors. Heavy menses and low consumption of red meat were found to be associated with the severity of anemia. Our findings may be useful for healthcare planners and policy makers in increasing efforts to reduce the prevalence and severity of iron deficiency anemia among women in Jordan.
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- Effects of micronised dispersible ferric pyrophosphate combined with alpha-lactalbumin in pregnant women affected by iron deficiency anemia: results from a prospective, double-blind, randomized controlled trial. [Randomized Controlled Trial]Eur Rev Med Pharmacol Sci. 2018 06; 22(11):3602-3608.ER
- CONCLUSIONS: Overall, MDFP-AL is more effective and safe than FG for the treatment of IDA in pregnant women.
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- Porous graphite: A facile synthesis from ferrous gluconate and excellent performance as anode electrocatalyst of microbial fuel cell. [Journal Article]Biosens Bioelectron. 2018 Jun 30; 109:116-122.BB
- A porous graphite (PG) is proposed as anode electrocatalyst of microbial fuel cell (MFC), which is synthesized by thermally decomposing ferrous gluconate followed by leaching iron. The physical characterizations from scanning electron microscopy, Brunauer-Emmett-Teller, X-ray diffraction, Raman spectroscopy, Fourier transform infrared spectroscopy, energy-dispersive X-ray spectroscopy, and X-ray …
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- Influence of iron redox state on black ripe olive processing. [Journal Article]J Sci Food Agric. 2018 Sep; 98(12):4653-4658.JS
- CONCLUSIONS: The results presented in this study suggest that the formation of ferric ions during the colour fixation step of black ripe olives must be avoided to obtain darker olives. Consequently, the initial pH of the ferrous gluconate solution must be corrected to avoid oxidation of the ferrous to ferric cations during the fixation step. This study will contribute to the improvement of the colour fixation step of black ripe olive processing. © 2018 Society of Chemical Industry.
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- Changes in Iron Absorption After Roux-en-Y Gastric Bypass. [Journal Article]
- CONCLUSIONS: RYGB adversely affects the absorption of ferrous fumarate tablets but not that of solubilized ferrous gluconate. A solubilized supplement is therefore preferred as the supplement of first choice after RYGB.
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- Estimates of total body iron indicate 19 mg and 38 mg oral iron are equivalent for the mitigation of iron deficiency in individuals experiencing repeated phlebotomy. [Journal Article]
- Iron deficiency anemia is a common clinical condition often treated with tablets containing 65 mg of elemental iron. Such doses can elicit gastrointestinal side effects lowering patient compliance. Oral iron supplements also increase hepcidin production causing decreased fractional absorption of subsequent doses. Frequent blood donors often become iron deficient. Therefore, they were enrolled in …
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- Analyses of Ferrous and Ferric State in DynabiTab Using Mössbauer Spectroscopy. [Journal Article]Int J Anal Chem. 2017; 2017:9321896.IJ
- Antianemic medicament ferrous gluconate, ferrous fumarate, and a Dynabi tablet with a basic iron bearing ingredient were studied with the use of Mössbauer spectroscopy. Room temperature spectra of ferrous gluconate gave clear evidence that the two phases of iron were present: ferrous (Fe2+) as a major one with a contribution at and above 91 a.u.% and ferric (Fe3+) whose contribution was found to …
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- Effects of different proteases on iron absorption property of egg white hydrolysates. [Journal Article]
- One of the causes of iron deficiency in human is poor absorption of non-heme iron from the diet. While proteins from meats have been reported in the literature to enhance the absorption of non-heme iron, other proteins, such as those from egg, are known to inhibit iron absorption. The objective of this study is to investigate non-heme iron binding property of egg white proteins hydrolyzed using p…
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- Sustainable Hydrothermal Carbonization Synthesis of Iron/Nitrogen-Doped Carbon Nanofiber Aerogels as Electrocatalysts for Oxygen Reduction. [Journal Article]
- It is urgent to develop new kinds of low-cost and high-performance nonprecious metal (NPM) catalysts as alternatives to Pt-based catalysts for oxygen reduction reaction (ORR) in fuel cells and metal-air batteries, which have been proved to be efficient to meet the challenge of increase of global energy demand and CO2 emissions. Here, an economical and sustainable method is developed for the synth…
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- Effect of iron supplementation on iron stores and total body iron after whole blood donation. [Randomized Controlled Trial]
- CONCLUSIONS: Donors on iron supplementation replaced donated iron while donors not on iron did not. Eight weeks of iron supplementation provided nearly all of the measured improvement in TBI. Daily iron supplementation after blood donation allows blood donors to recover the iron loss from blood donation and prevents sustained iron deficiency.
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- Iron Supplements and Magnesium Peroxide: An Example of a Hazardous Combination in Self-Medication. [Journal Article]
- The use of self-medication, which includes dietary supplements and over-the-counter drugs, is still on the rise, while safety issues are not well addressed yet. This especially holds for combinations. For example, iron supplements and magnesium peroxide both produce adverse effects via the formation of reactive oxygen species (ROS). This prompted us to investigate the effect of the combination of…
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