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Unbound Medicine.
(Apo Flurbiprofen)
2,898 results
  • Necrotizing Sialometaplasia: A Diagnostic Challenge to Oral Physicians. [Case Reports]
    Cureus. 2022 Dec; 14(12):e33122.Senthilnathan N, Rajaram Mohan K, … Pethagounder Thangavelu R
  • Necrotizing sialometaplasia is a rare, reactive, self-limiting disorder affecting a minor salivary gland that clinically mimics malignancy. Chronic smoking, alcohol use, trauma to the hard palate caused by local anesthetic injection due to the vasoconstrictive action of adrenaline in local anesthetic, topical application of nonsteroidal anti-inflammatory drugs like flurbiprofen spray used in bron…
  • Preparation and evaluation of oral soft chewable jelly containing flurbiprofen. [Journal Article]
    J Adv Pharm Technol Res. 2022 Oct-Dec; 13(4):306-311.Sabri LA, Khasraghi AH, Sulaiman HT
  • Oral jelly is a semisolid preparation that could resolve problem associated with dosage form's swallowing, especially in pediatric and elderly ones. This work aimed to prepare oral flurbiprofen (FBP) jelly to improve patient compliance. Heating and congealing method was used to prepare FBP jelly using three different polymers (pectin, sodium carboxymethyl cellulose, and hydroxypropyl methylcellul…
  • Gem-Difluoroallylation of Aryl Sulfonium Salts. [Journal Article]
    Org Lett. 2022 12 09; 24(48):8753-8758.Zhao Y, Empel C, … Patureau FW
  • The unprecedented photochemical late-stage defluorinative gem-difluoroallylation of aryl sulfonium salts, which are formed site-selectively by direct C(sp2)─H functionalization, is herein disclosed. This method is distinguished by its mild reaction conditions, wide scope, and excellent site-selectivity. As showcase examples, a Flurbiprofen and Pyriproxyfen derivatives could be late stage C(sp2)─H…
  • Clinical analysis of subxiphoid vs. lateral approaches for treating early anterior mediastinal thymoma. [Review]
    Front Surg. 2022; 9:984043.Li B, Niu L, … Chen S
  • CONCLUSIONS: Compared with the lateral intercostal thoracic approach, the subxiphoid approach had advantages in terms of intraoperative blood loss, postoperative hospital stay, tube extubation time, postoperative pleural drainage volume, postoperative VAS pain score, and analgesics dosage. It could provide a better view of the bilateral pleural cavities and more thorough thymectomy and superior cosmesis, and it proved to be a safe and feasible minimally invasive surgical method.
  • Fluorotelomer alcohols are efficiently biotransformed by Cunninghamella elegans. [Journal Article]
    Environ Sci Pollut Res Int. 2022 Nov 03 [Online ahead of print]Khan MF, Murphy CD
  • Cunninghamella elegans is a well-studied fungus that biotransforms a range of xenobiotics owing to impressive cytochrome P450 (CYP) activity. In this paper, we report the biotransformation of 6:2 fluorotelomer alcohol (6:2 FTOH) by the fungus, yielding a range of fluorinated products that were detectable by fluorine-19 nuclear magnetic resonance spectroscopy (19F NMR), gas chromatography-mass spe…
  • Anticancer ruthenium(II) tris(pyrazolyl)methane complexes with bioactive co-ligands. [Journal Article]
    Dalton Trans. 2022 Nov 15; 51(44):17050-17063.Gobbo A, Pereira SAP, … Marchetti F
  • In comparison with RuII-arene compounds, the medicinal potential of homologous RuII-tpm compounds [tpm = tris(pyrazolyl)methane] is underexplored. Pyridine, 4-pyridinemethanol and four functionalized pyridines, synthesized from the esterification of 4-pyridinemethanol with bioactive carboxylic acids (i.e., ethacrynic acid, ibuprofen, flurbiprofen and naproxen), react with the precursor [RuCl(κ3-t…
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